WO2008036617A2 - Low-calorie food and beverages - Google Patents

Low-calorie food and beverages Download PDF

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Publication number
WO2008036617A2
WO2008036617A2 PCT/US2007/078701 US2007078701W WO2008036617A2 WO 2008036617 A2 WO2008036617 A2 WO 2008036617A2 US 2007078701 W US2007078701 W US 2007078701W WO 2008036617 A2 WO2008036617 A2 WO 2008036617A2
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WO
WIPO (PCT)
Prior art keywords
fat
texture
food
low
inulin
Prior art date
Application number
PCT/US2007/078701
Other languages
French (fr)
Other versions
WO2008036617A3 (en
Inventor
Masahiro Hirano
Akifumi Tsuruta
Original Assignee
The Coca-Cola Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Coca-Cola Company filed Critical The Coca-Cola Company
Priority to EP07842649A priority Critical patent/EP2073649B1/en
Priority to ES07842649T priority patent/ES2376670T3/en
Priority to MX2009002665A priority patent/MX2009002665A/en
Priority to CA002662568A priority patent/CA2662568A1/en
Priority to AT07842649T priority patent/ATE531282T1/en
Publication of WO2008036617A2 publication Critical patent/WO2008036617A2/en
Publication of WO2008036617A3 publication Critical patent/WO2008036617A3/en

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Classifications

    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/38Other non-alcoholic beverages
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23FCOFFEE; TEA; THEIR SUBSTITUTES; MANUFACTURE, PREPARATION, OR INFUSION THEREOF
    • A23F5/00Coffee; Coffee substitutes; Preparations thereof
    • A23F5/24Extraction of coffee; Coffee extracts; Making instant coffee
    • A23F5/243Liquid, semi-liquid or non-dried semi-solid coffee extract preparations; Coffee gels; Liquid coffee in solid capsules
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L11/00Pulses, i.e. fruits of leguminous plants, for production of food; Products from legumes; Preparation or treatment thereof
    • A23L11/60Drinks from legumes, e.g. lupine drinks
    • A23L11/65Soy drinks
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52Adding ingredients
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/20Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
    • A23L29/206Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin
    • A23L29/244Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin from corms, tubers or roots, e.g. glucomannan
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • A23L33/175Amino acids
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/20Reducing nutritive value; Dietetic products with reduced nutritive value
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/20Reducing nutritive value; Dietetic products with reduced nutritive value
    • A23L33/21Addition of substantially indigestible substances, e.g. dietary fibres
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/20Reducing nutritive value; Dietetic products with reduced nutritive value
    • A23L33/21Addition of substantially indigestible substances, e.g. dietary fibres
    • A23L33/22Comminuted fibrous parts of plants, e.g. bagasse or pulp
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00Function of food ingredients
    • A23V2200/12Replacer
    • A23V2200/124Fat replacer

Definitions

  • This invention relates to food and beverages having low calories. More particularly, the invention is directed to non-fat or low fat food and beverages having a flavor, body, and the texture of fat.
  • non-fat or low-fat food and beverages with low calories are becoming popular, and low-calorie food and beverages that maintain a flavor, body and the texture of fat are desired.
  • Conventional non-fat or low-fat food and beverage products have lower calories by reducing their fat content; however, they lose fat's texture, body, and smooth taste, and their flavors decrease due to the reduced milk fat.
  • non-fat or low-fat food and beverages having low calories and that offer a flavor, body and fat's texture are desired.
  • a food and beverage product having a fat-like texture substance containing inulin as a main ingredient and polyglutamic acid.
  • a non-fat or low-fat food and beverage product having low calories and that offers a flavor, body and fat's texture is achieved.
  • a low-calorie food and beverage product of this invention has a fat-like texture substance containing inulin as a main ingredient and polyglutamic acid. By having these ingredients, it is possible to obtain a low- calorie food and beverage product that has a flavor, body, and fat's texture.
  • the term "food and beverage product” refers to a food product, a beverage product, or a combination of both.
  • the beverage product may include coffee drink, milk tea, tea drink, juice, vegetable juice, carbonated drink, milk-related drink, lactic acid drink, soy milk, energy drink, other soft drinks, jelly-type drink, and any other beverage suitable for this invention.
  • the food product may include pudding, yogurt, jelly, snacks, and any other food the skilled artisan would consider suitable.
  • the term fat-like texture substance refers to a substance that adds or improves fat's texture of food and beverage products due to interactions between inulin and polyglutaminic acid when the substance is added to the food and beverage products.
  • the fat's texture includes, for example, the texture of milk fat. Inulin and polyglutaminic acid do not have to be mixed beforehand, and each of them can be added at appropriate times during a manufacturing process of the food and beverage products.
  • inulin as a main ingredient means that in a food and beverage product containing inulin and polyglutaminic acid, more inulin is contained in the product than polyglutaminic acid in weight.
  • inulin is contained in the product about 100 to 250 times more in weight than polyglutamic acid.
  • Inulin is an oligosaccharide produced by chicory, an artichoke, an onion, a leek, garlic, a burdock, a banana, etc.
  • Inulin is a water-soluble dietary fiber, and it forms fat-formed cream when dissolved in water and has fat's texture. Inulin can be obtained, for example, by adding glycosyltransferase to a sterilized sugar solution that is made of a refined sugar product as raw materials.
  • Polyglutaminic acid is known as a chief ingredient of a stickiness substance in natto (fermented soybeans). Polyglutaminic acid has many negative ions and promotes an absorption of minerals, such as calcium. Moreover, polyglutaminic acid has water-retention (humidity retention) characteristics and hydrophilicity. As polyglutaminic acid, it is preferable to use a polymer of an amino acid including D-glutaminic acid and L-glutaminic acid.
  • the low-calorie food and beverage product may include powdered skim milk.
  • the fat-like texture substance with powdered skim milk may provide a flavor and body while achieving reduced milk fat.

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Agronomy & Crop Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Dairy Products (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Tea And Coffee (AREA)
  • Non-Alcoholic Beverages (AREA)
  • Confectionery (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

A non-fat or low-fat food and beverage product having low calories is provided. The product offers a flavor, body and fat's texture. The food and beverage product includes a fat-like texture substance containing inulin as a main ingredient and polyglutamic acid.

Description

LOW-CALORIE FOOD AND BEVERAGES
DESCRIPTION OF THE INVENTION
Cross Reference to Related Application
[001] This application is based upon and claims the benefit of priority from Japanese Patent Application No. 2006-257887, filed September 22, 2006, and U.S. Application Serial No. 11/525,829, filed September 25, 2006, the entire content of which is incorporated herein by reference.
Field of the Invention
[002] This invention relates to food and beverages having low calories. More particularly, the invention is directed to non-fat or low fat food and beverages having a flavor, body, and the texture of fat.
Background of the Invention
[003] Recently, non-fat or low-fat food and beverages with low calories are becoming popular, and low-calorie food and beverages that maintain a flavor, body and the texture of fat are desired. Conventional non-fat or low-fat food and beverage products have lower calories by reducing their fat content; however, they lose fat's texture, body, and smooth taste, and their flavors decrease due to the reduced milk fat.
[004] In an effort to solve this problem, flavoring additives were added; however, it still could not achieve desired body. In addition, for example, a substance for beverages that contains polyamino acid from natto (fermented soybean) bacillus as the main ingredient is suggested (see Japanese Laid- Open Patent H2-249474), but low-calorie food and beverages with fat's texture were not realized.
[005] Therefore, non-fat or low-fat food and beverages having low calories and that offer a flavor, body and fat's texture are desired.
SUMMARY OF THE INVENTION
[006] It is accordingly an object of the invention to provide non-fat or low-fat food and beverages having low calories and that offer a flavor, body and fat's texture. In accordance with the invention, a food and beverage product having a fat-like texture substance containing inulin as a main ingredient and polyglutamic acid.
[007] Additional objects and advantages of the invention will be set forth in part in the description which follows, and in part will be obvious from the description, or may be learned by practice of the invention. The objects and advantages of the invention will be realized and attained by means of the elements and combinations particularly pointed out in the appended claims. It is to be understood that both the foregoing general description and the following detailed description are exemplary and explanatory only and are not restrictive of the invention, as claimed.
DESCRIPTION OF THE EMBODIMENTS
[008] Reference will now be made in detail to the present exemplary embodiments of the invention. The inventors of this patent application used inulin in order to produce non-fat or low-fat coffee drink with a flavor, body, and fat's texture. The inventors realized that in order to achieve desired fat texture, it was necessary to add an increased amount of inulin. However, while the added amount of inulin provided fat texture, it became powder-like and resulted in a bad aftertaste. The inventor realized that by adding a fat-like texture substance containing inulin as a main ingredient and a small amount of polyglutamic acid, the powderiness issue was resolved and improved flavor, body, and fat's texture were obtained.
[009] According to this invention, a non-fat or low-fat food and beverage product having low calories and that offers a flavor, body and fat's texture is achieved.
[010] One exemplary embodiment according to the invention is explained. It is intended that the embodiment should be considered as exemplary only.
[011] A low-calorie food and beverage product of this invention has a fat-like texture substance containing inulin as a main ingredient and polyglutamic acid. By having these ingredients, it is possible to obtain a low- calorie food and beverage product that has a flavor, body, and fat's texture.
[012] Throughout the specification, the term "food and beverage product" refers to a food product, a beverage product, or a combination of both. The beverage product may include coffee drink, milk tea, tea drink, juice, vegetable juice, carbonated drink, milk-related drink, lactic acid drink, soy milk, energy drink, other soft drinks, jelly-type drink, and any other beverage suitable for this invention. The food product may include pudding, yogurt, jelly, snacks, and any other food the skilled artisan would consider suitable. [013] Also, the term fat-like texture substance refers to a substance that adds or improves fat's texture of food and beverage products due to interactions between inulin and polyglutaminic acid when the substance is added to the food and beverage products. The fat's texture includes, for example, the texture of milk fat. Inulin and polyglutaminic acid do not have to be mixed beforehand, and each of them can be added at appropriate times during a manufacturing process of the food and beverage products.
[014] Moreover, the term "inulin as a main ingredient" means that in a food and beverage product containing inulin and polyglutaminic acid, more inulin is contained in the product than polyglutaminic acid in weight. Preferably, inulin is contained in the product about 100 to 250 times more in weight than polyglutamic acid. By containing inulin and polyglutamic acid at these ratios, improved results may be obtained.
[015] In case of a beverage product, it is preferable to contain 3-20 gram/liter (g/L) of inulin and 0.02-0.05 g/L of polyglutaminic acid.
[016] Inulin is an oligosaccharide produced by chicory, an artichoke, an onion, a leek, garlic, a burdock, a banana, etc. Inulin is a water-soluble dietary fiber, and it forms fat-formed cream when dissolved in water and has fat's texture. Inulin can be obtained, for example, by adding glycosyltransferase to a sterilized sugar solution that is made of a refined sugar product as raw materials.
[017] Polyglutaminic acid is known as a chief ingredient of a stickiness substance in natto (fermented soybeans). Polyglutaminic acid has many negative ions and promotes an absorption of minerals, such as calcium. Moreover, polyglutaminic acid has water-retention (humidity retention) characteristics and hydrophilicity. As polyglutaminic acid, it is preferable to use a polymer of an amino acid including D-glutaminic acid and L-glutaminic acid.
[018] In addition, the low-calorie food and beverage product may include powdered skim milk. In certain beverages, such as coffee drink and beverages that usually contain a milk ingredient, the fat-like texture substance with powdered skim milk may provide a flavor and body while achieving reduced milk fat.
[019] Examples:
[020] Examples are described below. The scope of the invention should not be limited by the examples. Other examples will be apparent to those skilled in the art from consideration of the specification and practice of the invention disclosed herein.
[021] [Manufacture of Samples C-5-C-7]
[022] 30 grams of R & G coffee (powder coffee) was extracted with 95°C of hot water and prepared to contain 7.5 grams of coffee solidity. Next, 35 grams of sugar, 0.6 grams of emulsifier, and 20.5 grams of powdered skim milk were subsequently added to the coffee and dissolved. Then, inulin (FujiFF made by Fuji Nihon Sugar Refining Company) and γ-PGA (y- poly glutaminic acid) (a product made by Ajinomoto) were mixed at concentration indicated at Table 2 and dissolved. Finally, 0.85 grams of sodium bicarbonate and 1 gram of flavoring agent were mixed, and water was added to the mixture, and 1 liter of coffee drink was prepared. The coffee drink was packaged in cans and sterilized them in a retort, and each sample (C-5~C-7, comparison example (Control) 1 , 2) was made. Compositions of samples are shown in Table 1.
[023] [Table 1]
Figure imgf000007_0001
[024] [Table 2]
Figure imgf000007_0002
[025] [Evaluation]
[026] Five coffee samples made by the above method were evaluated. A tasting test by six panel members who had experience in drink development was performed. The panel members evaluated the samples for their fat texture and powderiness (roughness). Each sample was graded for its fat texture on a scale of 0-10 points. Comparison Example 1 (Control 1) was graded as 5, and a higher number indicated more fat texture. Each sample was also graded for its powderiness on a scale of 0-10 points. Comparison Example 1 (Control 1) was graded as 5, and a higher number indicated more powderiness. Table 3 shows the average score of the six panel members. [027] [Table 3]
Figure imgf000008_0001
[028] As indicated by Table 3, enough fat texture was not achieved with adding only inulin, and with a high concentration of inulin, as in Control 2, the fat texture was improved, but the powderiness and aftertaste were not satisfactory. In contrast, C-5~C-7 provided improved fat texture and reduced powderiness. Also, these samples provided excellent body and flavor.
[029] Moreover, another comparison was made with a product containing the same amount of inulin and polyglutaminic acid, and it was found that the product failed to provide sufficient body and flavor.
[030] Other embodiments of the invention will be apparent to those skilled in the art from consideration of the specification and practice of the invention disclosed herein. It is intended that the specification and examples be considered as exemplary only, with a true scope and spirit of the invention being indicated by the following claims.

Claims

WHAT IS CLAIMED IS:
1. A food and beverage product, comprising a fat-like texture substance containing inulin as a main ingredient and poiyglutamic acid.
2. The product of claim 1 , wherein the fat-like texture substance contains the inulin about 100 to 250 times more in weight than the poiyglutamic acid.
3. The product of claim 1 , further comprising powdered skim milk.
4. The product of claim 2, further comprising powdered skim milk.
PCT/US2007/078701 2006-09-22 2007-09-18 Low-calorie food and beverages WO2008036617A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
EP07842649A EP2073649B1 (en) 2006-09-22 2007-09-18 Low-calorie food and beverages
ES07842649T ES2376670T3 (en) 2006-09-22 2007-09-18 FOOD AND BEVERAGES THAT HAVE FEW HEAT.
MX2009002665A MX2009002665A (en) 2006-09-22 2007-09-18 Low-calorie food and beverages.
CA002662568A CA2662568A1 (en) 2006-09-22 2007-09-18 Low-calorie food and beverages
AT07842649T ATE531282T1 (en) 2006-09-22 2007-09-18 LOW CALORIE FOODS AND DRINKS

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2006-257887 2006-09-22
JP2006257887A JP2008072993A (en) 2006-09-22 2006-09-22 Low-calorie food and drink
US11/525,829 US7867546B2 (en) 2006-09-22 2006-09-25 Low-calorie food and beverages
US11/525,829 2006-09-25

Publications (2)

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WO2008036617A2 true WO2008036617A2 (en) 2008-03-27
WO2008036617A3 WO2008036617A3 (en) 2008-10-23

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CN (1) CN101528068A (en)
AT (1) ATE531282T1 (en)
CA (1) CA2662568A1 (en)
ES (1) ES2376670T3 (en)
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JP5493120B2 (en) * 2009-07-29 2014-05-14 伊那食品工業株式会社 Lipid substitutes, lipid substitutes, and low-calorie foods
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US5527556A (en) * 1991-10-04 1996-06-18 Raffinerie Tirlemontoise S.A. Compositions having a creamy structure and containing fructan, process for preparing these compositions and their use
US5721004A (en) * 1996-03-01 1998-02-24 Kraft Foods, Inc. Method for producing fat-free and low-fat viscous dressings using inulin
EP0821885A1 (en) * 1996-07-31 1998-02-04 "Raffinerie Tirlemontoise", société anonyme: Fructan- and/or polydextrose-containing dairy powders, process for preparing same and their use
WO2006033162A1 (en) * 2004-09-24 2006-03-30 Fukuoka Soy Sauce Brewing Cooperation Composition for denture stabilization
WO2006035979A1 (en) * 2004-09-29 2006-04-06 Asama Chemical Co., Ltd. Functional composition or food containing whey protein, antibody derived from milk, or antibody

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EP2073649A2 (en) 2009-07-01
US7867546B2 (en) 2011-01-11
CA2662568A1 (en) 2008-03-27
EP2073649B1 (en) 2011-11-02
ATE531282T1 (en) 2011-11-15
CN101528068A (en) 2009-09-09
KR20090053818A (en) 2009-05-27
JP2008072993A (en) 2008-04-03
US20080075831A1 (en) 2008-03-27
ES2376670T3 (en) 2012-03-15
WO2008036617A3 (en) 2008-10-23
MX2009002665A (en) 2009-03-24

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