WO2008035343A3 - Artificial receptors - Google Patents

Artificial receptors Download PDF

Info

Publication number
WO2008035343A3
WO2008035343A3 PCT/IL2007/001159 IL2007001159W WO2008035343A3 WO 2008035343 A3 WO2008035343 A3 WO 2008035343A3 IL 2007001159 W IL2007001159 W IL 2007001159W WO 2008035343 A3 WO2008035343 A3 WO 2008035343A3
Authority
WO
WIPO (PCT)
Prior art keywords
artificial receptors
monolayer
binding
artificial receptor
artificial
Prior art date
Application number
PCT/IL2007/001159
Other languages
French (fr)
Other versions
WO2008035343A2 (en
Inventor
Uri Sivan
Yoram Reiter
Arbel Artzy-Schnirman
Original Assignee
Technion Res & Dev Foundation
Uri Sivan
Yoram Reiter
Arbel Artzy-Schnirman
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/524,264 external-priority patent/US20080076670A1/en
Application filed by Technion Res & Dev Foundation, Uri Sivan, Yoram Reiter, Arbel Artzy-Schnirman filed Critical Technion Res & Dev Foundation
Priority to US12/311,216 priority Critical patent/US8354066B2/en
Publication of WO2008035343A2 publication Critical patent/WO2008035343A2/en
Publication of WO2008035343A3 publication Critical patent/WO2008035343A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)

Abstract

Antibodies are provided. For as example, an antibody capable of binding an artificial receptor which comprises a hydroquinone monolayer and is incapable of binding the artificial receptor when comprising a benzoquinone monolayer. Also provided are methods and systems using same for control delivery of a molecule-of-interest into a tissue.
PCT/IL2007/001159 2004-03-24 2007-09-20 Artificial receptors WO2008035343A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US12/311,216 US8354066B2 (en) 2004-03-24 2007-09-20 Artificial receptors

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/524,264 US20080076670A1 (en) 2004-03-24 2006-09-21 Artificial receptors
US11/524,264 2006-09-21

Publications (2)

Publication Number Publication Date
WO2008035343A2 WO2008035343A2 (en) 2008-03-27
WO2008035343A3 true WO2008035343A3 (en) 2008-12-04

Family

ID=39200960

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2007/001159 WO2008035343A2 (en) 2004-03-24 2007-09-20 Artificial receptors

Country Status (1)

Country Link
WO (1) WO2008035343A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8354066B2 (en) 2004-03-24 2013-01-15 Technion Research & Development Foundation Ltd. Artificial receptors

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998000107A2 (en) * 1996-07-02 1998-01-08 Massachusetts Institute Of Technology Microchip drug delivery devices
WO2002013785A2 (en) * 2000-08-14 2002-02-21 Pharmacia Corporation Drug delivery system with burst electrode
WO2005090981A2 (en) * 2004-03-24 2005-09-29 Technion Research & Development Foundation Ltd. Electrode

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998000107A2 (en) * 1996-07-02 1998-01-08 Massachusetts Institute Of Technology Microchip drug delivery devices
WO2002013785A2 (en) * 2000-08-14 2002-02-21 Pharmacia Corporation Drug delivery system with burst electrode
WO2005090981A2 (en) * 2004-03-24 2005-09-29 Technion Research & Development Foundation Ltd. Electrode

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ROMBACH E M ET AL: "Detection of benzoquinone adducts to rat liver protein sulfhydryl groups using specific antibodies.", CHEMICAL RESEARCH IN TOXICOLOGY DEC 1997, vol. 10, no. 12, December 1997 (1997-12-01), pages 1407 - 1411, XP002474765, ISSN: 0893-228X *
SHASTRI V R ET AL: "BIOMEDICAL APPLICATIONS OF ELECTROACTIVE POLYMERS", ELECTRICAL AND OPTICAL POLYMER SYSTEMS, MARCEL DEKKER, NEW YORK, NY, US, 1 January 1998 (1998-01-01), pages 1031 - 1051, XP000874992 *

Also Published As

Publication number Publication date
WO2008035343A2 (en) 2008-03-27

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