WO2008034129A3 - Treatment of cancer or obesity with conjugated linoleic acids - Google Patents

Treatment of cancer or obesity with conjugated linoleic acids Download PDF

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Publication number
WO2008034129A3
WO2008034129A3 PCT/US2007/078641 US2007078641W WO2008034129A3 WO 2008034129 A3 WO2008034129 A3 WO 2008034129A3 US 2007078641 W US2007078641 W US 2007078641W WO 2008034129 A3 WO2008034129 A3 WO 2008034129A3
Authority
WO
WIPO (PCT)
Prior art keywords
cancer
patients
obesity
treatment
conjugated linoleic
Prior art date
Application number
PCT/US2007/078641
Other languages
French (fr)
Other versions
WO2008034129A2 (en
Inventor
Dale E Bauman
Kevin J Harvatine
Original Assignee
Cornell Res Foundation Inc
Dale E Bauman
Kevin J Harvatine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cornell Res Foundation Inc, Dale E Bauman, Kevin J Harvatine filed Critical Cornell Res Foundation Inc
Publication of WO2008034129A2 publication Critical patent/WO2008034129A2/en
Publication of WO2008034129A3 publication Critical patent/WO2008034129A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism

Abstract

The present invention discloses a method of screening cancer or obesity patients to determine whether the form of cancer or obesity they have is suitable for treatment with conjugated linoleic acids as well as treating patients for cancer based on that determination. The screening identifies patients with tumor cells with a disregulation of lipid metabolism, patients who overexpress the Thyroid Hormone Responsive Spot 14 gene, and patients who overexpress the Sterol Responsive Element Binding Protein gene.
PCT/US2007/078641 2006-09-15 2007-09-17 Treatment of cancer or obesity with conjugated linoleic acids WO2008034129A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US84481506P 2006-09-15 2006-09-15
US60/844,815 2006-09-15

Publications (2)

Publication Number Publication Date
WO2008034129A2 WO2008034129A2 (en) 2008-03-20
WO2008034129A3 true WO2008034129A3 (en) 2008-11-20

Family

ID=39184647

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/078641 WO2008034129A2 (en) 2006-09-15 2007-09-17 Treatment of cancer or obesity with conjugated linoleic acids

Country Status (1)

Country Link
WO (1) WO2008034129A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110183870A1 (en) * 2008-08-28 2011-07-28 Yuanlong Pan Gene expression profiles associated with lean phenotype and uses thereof
US8809560B2 (en) 2011-05-17 2014-08-19 Board Of Trustees Of The University Of Arkansas Trans-, trans-conjugated linoleic acid compositions and use thereof
US9375433B2 (en) 2012-09-26 2016-06-28 Tangent Reprofiling Limited Modulators of androgen synthesis
WO2014049071A1 (en) * 2012-09-26 2014-04-03 Tangent Reprofiling Limited Modulators of androgen synthesis
US9062276B2 (en) 2012-12-03 2015-06-23 Board Of Trustees Of The University Of Arkansas Conjugated linoleic acid rich vegetable oil production from linoleic rich oils by heterogeneous catalysis
CN112569218A (en) * 2020-12-21 2021-03-30 自然资源部第一海洋研究所 Application of conjugated linoleic acid isomer in preparation of medicines and health products for reducing visceral fat content

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BASU S. ET AL.: "Conjugated Linoleic Acid Induces Lipid Peroxidation in Humans", FEBS LETTERS, vol. 468, no. 1, 2000, pages 33 - 36, XP004260993 *

Also Published As

Publication number Publication date
WO2008034129A2 (en) 2008-03-20

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