WO2008033368A3 - Boroproline compound and cytokine combination therapy - Google Patents

Boroproline compound and cytokine combination therapy Download PDF

Info

Publication number
WO2008033368A3
WO2008033368A3 PCT/US2007/019767 US2007019767W WO2008033368A3 WO 2008033368 A3 WO2008033368 A3 WO 2008033368A3 US 2007019767 W US2007019767 W US 2007019767W WO 2008033368 A3 WO2008033368 A3 WO 2008033368A3
Authority
WO
WIPO (PCT)
Prior art keywords
combination therapy
cytokine combination
boroproline
boroproline compound
compound
Prior art date
Application number
PCT/US2007/019767
Other languages
French (fr)
Other versions
WO2008033368A2 (en
Inventor
Nazneen Aziz
Original Assignee
Dara Biosciences Inc
Nazneen Aziz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dara Biosciences Inc, Nazneen Aziz filed Critical Dara Biosciences Inc
Publication of WO2008033368A2 publication Critical patent/WO2008033368A2/en
Publication of WO2008033368A3 publication Critical patent/WO2008033368A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5023—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on expression patterns
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A method is provided for treating subjects with boroproline compound and cytokine combination therapy. The invention further provides methods for identifying subjects that are likely to respond to boroproline treatment.
PCT/US2007/019767 2006-09-12 2007-09-12 Boroproline compound and cytokine combination therapy WO2008033368A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US84385406P 2006-09-12 2006-09-12
US60/843,854 2006-09-12

Publications (2)

Publication Number Publication Date
WO2008033368A2 WO2008033368A2 (en) 2008-03-20
WO2008033368A3 true WO2008033368A3 (en) 2009-05-07

Family

ID=39184306

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/019767 WO2008033368A2 (en) 2006-09-12 2007-09-12 Boroproline compound and cytokine combination therapy

Country Status (1)

Country Link
WO (1) WO2008033368A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2711380C2 (en) 2015-07-16 2020-01-16 Байоксэл Терапьютикс, Инк. New approach to treating cancer with application of immunomodulation
CA3121270A1 (en) * 2018-12-10 2020-06-18 Bioxcel Therapeutics, Inc. Novel approach for treatment of cancer using immunomodulation

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040077601A1 (en) * 2002-07-09 2004-04-22 Point Therapeutics, Inc. Methods and compositions relating to isoleucine boroproline compounds

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040077601A1 (en) * 2002-07-09 2004-04-22 Point Therapeutics, Inc. Methods and compositions relating to isoleucine boroproline compounds

Also Published As

Publication number Publication date
WO2008033368A2 (en) 2008-03-20

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