WO2008030278A3 - Assays for radiation exposure - Google Patents

Assays for radiation exposure Download PDF

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Publication number
WO2008030278A3
WO2008030278A3 PCT/US2007/011800 US2007011800W WO2008030278A3 WO 2008030278 A3 WO2008030278 A3 WO 2008030278A3 US 2007011800 W US2007011800 W US 2007011800W WO 2008030278 A3 WO2008030278 A3 WO 2008030278A3
Authority
WO
WIPO (PCT)
Prior art keywords
biological sample
assays
radiation exposure
detecting
exposed
Prior art date
Application number
PCT/US2007/011800
Other languages
French (fr)
Other versions
WO2008030278A2 (en
Inventor
Derek L Stirewalt
Original Assignee
Hutchinson Fred Cancer Res
Derek L Stirewalt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hutchinson Fred Cancer Res, Derek L Stirewalt filed Critical Hutchinson Fred Cancer Res
Publication of WO2008030278A2 publication Critical patent/WO2008030278A2/en
Publication of WO2008030278A3 publication Critical patent/WO2008030278A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The present invention provides a method of detecting or determining, and the use of a means of detecting or determining, if a biological sample has been exposed to ionizing radiation. The invention is carried out by detecting a change in expression of at least one preselected gene in a biological sample, the change in expression indicating that the biological sample, or a subject from which the biological sample has been collected, has been exposed to a ionizing radiation.
PCT/US2007/011800 2006-06-05 2007-05-17 Assays for radiation exposure WO2008030278A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81093606P 2006-06-05 2006-06-05
US60/810,936 2006-06-05

Publications (2)

Publication Number Publication Date
WO2008030278A2 WO2008030278A2 (en) 2008-03-13
WO2008030278A3 true WO2008030278A3 (en) 2008-06-12

Family

ID=39157725

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/011800 WO2008030278A2 (en) 2006-06-05 2007-05-17 Assays for radiation exposure

Country Status (1)

Country Link
WO (1) WO2008030278A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2580240T (en) 2010-06-14 2019-03-29 Lykera Biomed S A S100a4 antibodies and therapeutic uses thereof
WO2012162049A2 (en) * 2011-05-20 2012-11-29 Fred Hutchinson Cancer Research Center Methods and compositions for measuring radiation exposure in a subject

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7008768B1 (en) * 1999-02-26 2006-03-07 The United States Of America As Represented By The Department Of Health And Human Services Method for detecting radiation exposure

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7008768B1 (en) * 1999-02-26 2006-03-07 The United States Of America As Represented By The Department Of Health And Human Services Method for detecting radiation exposure

Also Published As

Publication number Publication date
WO2008030278A2 (en) 2008-03-13

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