WO2008017000A3 - Methods and pharmaceutical preparations for contributing to the treatment of chemotherapy-induced neuropathy - Google Patents

Methods and pharmaceutical preparations for contributing to the treatment of chemotherapy-induced neuropathy Download PDF

Info

Publication number
WO2008017000A3
WO2008017000A3 PCT/US2007/075008 US2007075008W WO2008017000A3 WO 2008017000 A3 WO2008017000 A3 WO 2008017000A3 US 2007075008 W US2007075008 W US 2007075008W WO 2008017000 A3 WO2008017000 A3 WO 2008017000A3
Authority
WO
WIPO (PCT)
Prior art keywords
chemotherapy
treatment
methods
pharmaceutical preparations
contributing
Prior art date
Application number
PCT/US2007/075008
Other languages
French (fr)
Other versions
WO2008017000A8 (en
WO2008017000A2 (en
Inventor
Guru Reddy
Doria Mirejovsky
Luigi Lenaz
Original Assignee
Spectrum Pharmaceuticals Inc
Guru Reddy
Doria Mirejovsky
Luigi Lenaz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spectrum Pharmaceuticals Inc, Guru Reddy, Doria Mirejovsky, Luigi Lenaz filed Critical Spectrum Pharmaceuticals Inc
Priority to CA002659477A priority Critical patent/CA2659477A1/en
Priority to JP2009523049A priority patent/JP2009545619A/en
Priority to EP07840646A priority patent/EP2046335A2/en
Priority to MX2009001116A priority patent/MX2009001116A/en
Priority to BRPI0715504-2A priority patent/BRPI0715504A2/en
Publication of WO2008017000A2 publication Critical patent/WO2008017000A2/en
Publication of WO2008017000A3 publication Critical patent/WO2008017000A3/en
Priority to NO20090279A priority patent/NO20090279L/en
Priority to IL196824A priority patent/IL196824A0/en
Publication of WO2008017000A8 publication Critical patent/WO2008017000A8/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Methods and pharmaceutical preparations for using a leteprinim suspension to contribute to the treatment of chemotherapy-induced neuropathy.
PCT/US2007/075008 2006-08-01 2007-08-01 Methods and pharmaceutical preparations for contributing to the treatment of chemotherapy-induced neuropathy WO2008017000A2 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
CA002659477A CA2659477A1 (en) 2006-08-01 2007-08-01 Methods and pharmaceutical preparations for contributing to the treatment of chemotherapy-induced neuropathy
JP2009523049A JP2009545619A (en) 2006-08-01 2007-08-01 Methods and pharmaceutical formulations for contributing to the treatment of chemotherapy-induced neuropathy
EP07840646A EP2046335A2 (en) 2006-08-01 2007-08-01 Methods and pharmaceutical preparations for contributing to the treatment of chemotherapy-induced neuropathy
MX2009001116A MX2009001116A (en) 2006-08-01 2007-08-01 Methods and pharmaceutical preparations for contributing to the treatment of chemotherapy-induced neuropathy.
BRPI0715504-2A BRPI0715504A2 (en) 2006-08-01 2007-08-01 PHARMACEUTICAL METHODS AND PREPARATIONS TO CONTRIBUTE TO THE TREATMENT OF CHEMOTHERAPY-INDUCED NEUROPATHY.
NO20090279A NO20090279L (en) 2006-08-01 2009-01-19 Methods and Pharmaceutical Preparations to Assist in the Treatment of Chemotherapy-Induced Neuropathy
IL196824A IL196824A0 (en) 2006-08-01 2009-02-01 Methods and pharmaceutical preparations for contributing to the treatment of chemotherapy-induced neuropathy

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US82108206P 2006-08-01 2006-08-01
US60/821,082 2006-08-01

Publications (3)

Publication Number Publication Date
WO2008017000A2 WO2008017000A2 (en) 2008-02-07
WO2008017000A3 true WO2008017000A3 (en) 2008-03-20
WO2008017000A8 WO2008017000A8 (en) 2009-04-30

Family

ID=38744846

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/075008 WO2008017000A2 (en) 2006-08-01 2007-08-01 Methods and pharmaceutical preparations for contributing to the treatment of chemotherapy-induced neuropathy

Country Status (12)

Country Link
EP (1) EP2046335A2 (en)
JP (1) JP2009545619A (en)
KR (1) KR20090047501A (en)
CN (1) CN101657199A (en)
BR (1) BRPI0715504A2 (en)
CA (1) CA2659477A1 (en)
IL (1) IL196824A0 (en)
MX (1) MX2009001116A (en)
NO (1) NO20090279L (en)
RU (1) RU2009107123A (en)
WO (1) WO2008017000A2 (en)
ZA (1) ZA200900728B (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020055506A1 (en) * 2000-07-07 2002-05-09 Jack Diamond Methods for treatment of disease-induced peripheral neuropathy and related conditions

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020055506A1 (en) * 2000-07-07 2002-05-09 Jack Diamond Methods for treatment of disease-induced peripheral neuropathy and related conditions
US20020061899A1 (en) * 2000-07-07 2002-05-23 Jack Diamond Methods for treatment of drug-induced peripheral neuropathy and related conditions

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
CAVALETTI G ET AL: "Current status and future prospects for the treatment of chemotherapy-induced peripheral neurotoxicity", EUROPEAN JOURNAL OF CANCER, PERGAMON PRESS, OXFORD, GB, vol. 38, no. 14, September 2002 (2002-09-01), pages 1832 - 1837, XP004377449, ISSN: 0959-8049 *
HOLMES MICHAEL ET AL: "Neotrofin, a novel purine that induces NGF-dependent nociceptive nerve sprouting but not hyperalgesia in adult rat skin.", MOLECULAR AND CELLULAR NEUROSCIENCE, vol. 24, no. 3, November 2003 (2003-11-01), pages 568 - 580, XP002461145, ISSN: 1044-7431 *
REDDY ET AL: "221 POSTER Leteprinim attenuates cisplatin-induced neuropathy", EUROPEAN JOURNAL OF CANCER. SUPPLEMENT, PERGAMON, OXFORD, GB, vol. 4, no. 12, November 2006 (2006-11-01), pages 69, XP005810440, ISSN: 1359-6349 *
TAYLOR E M ET AL: "NEOTROFIN!TM PREVENTS VINCRISTINE - INDUCED PERIPHERAL NEUROPATHY IN THE RAT.", SOCIETY FOR NEUROSCIENCE ABSTRACT VIEWER AND ITINERARY PLANNER, vol. 2002, 2002, & 32ND ANNUAL MEETING OF THE SOCIETY FOR NEUROSCIENCE; ORLANDO, FLORIDA, USA; NOVEMBER 02-07, 2002, pages Abstract No. 842.5 URL - http://sf, XP009093269 *

Also Published As

Publication number Publication date
CA2659477A1 (en) 2008-02-07
CN101657199A (en) 2010-02-24
KR20090047501A (en) 2009-05-12
WO2008017000A8 (en) 2009-04-30
ZA200900728B (en) 2010-03-31
IL196824A0 (en) 2009-11-18
MX2009001116A (en) 2009-02-10
RU2009107123A (en) 2010-09-10
WO2008017000A2 (en) 2008-02-07
NO20090279L (en) 2009-02-26
BRPI0715504A2 (en) 2014-05-06
JP2009545619A (en) 2009-12-24
EP2046335A2 (en) 2009-04-15

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