WO2008011179A3 - Omega-3 fatty acids for use in treating resistant hypertension - Google Patents

Omega-3 fatty acids for use in treating resistant hypertension Download PDF

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Publication number
WO2008011179A3
WO2008011179A3 PCT/US2007/016527 US2007016527W WO2008011179A3 WO 2008011179 A3 WO2008011179 A3 WO 2008011179A3 US 2007016527 W US2007016527 W US 2007016527W WO 2008011179 A3 WO2008011179 A3 WO 2008011179A3
Authority
WO
WIPO (PCT)
Prior art keywords
resistant hypertension
omega
fatty acids
hypertension
compositions
Prior art date
Application number
PCT/US2007/016527
Other languages
French (fr)
Other versions
WO2008011179A2 (en
Inventor
Roelof M L Rongen
Douglas F Kling
Robert A Ms Shalwitz
Original Assignee
Reliant Pharmaceuticals Inc
Roelof M L Rongen
Douglas F Kling
Robert A Ms Shalwitz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reliant Pharmaceuticals Inc, Roelof M L Rongen, Douglas F Kling, Robert A Ms Shalwitz filed Critical Reliant Pharmaceuticals Inc
Priority to EP07810681A priority Critical patent/EP2049098A2/en
Priority to JP2009521786A priority patent/JP2009544702A/en
Publication of WO2008011179A2 publication Critical patent/WO2008011179A2/en
Publication of WO2008011179A3 publication Critical patent/WO2008011179A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Compositions comprising omega-3 fatty acids, where the compositions are useful for treating resistant hypertension, reducing blood pressure in a patient suffering from resistant hypertension, and/or controlling blood pressure in a patient suffering from resistant hypertension. The compositions are also useful in methods for treating resistant hypertension in a subject group of patients suffering from resitant hypertension, where the blood pressure of the subject group is reduced by a statistically significant amount as compared to a control group.
PCT/US2007/016527 2006-07-21 2007-07-23 Omega-3 fatty acids for use in treating resistant hypertension WO2008011179A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP07810681A EP2049098A2 (en) 2006-07-21 2007-07-23 Omega-3 fatty acids for use in treating resistant hypertension
JP2009521786A JP2009544702A (en) 2006-07-21 2007-07-23 Omega-3 fatty acids for the treatment of resistant hypertension

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83215606P 2006-07-21 2006-07-21
US60/832,156 2006-07-21

Publications (2)

Publication Number Publication Date
WO2008011179A2 WO2008011179A2 (en) 2008-01-24
WO2008011179A3 true WO2008011179A3 (en) 2008-06-12

Family

ID=38957421

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/016527 WO2008011179A2 (en) 2006-07-21 2007-07-23 Omega-3 fatty acids for use in treating resistant hypertension

Country Status (3)

Country Link
EP (1) EP2049098A2 (en)
JP (1) JP2009544702A (en)
WO (1) WO2008011179A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8343753B2 (en) 2007-11-01 2013-01-01 Wake Forest University School Of Medicine Compositions, methods, and kits for polyunsaturated fatty acids from microalgae
WO2010103402A1 (en) * 2009-03-09 2010-09-16 Pronova Biopharma Norge As Compositions comprising a fatty acid oil mixture comprising epa and dha in free acid form and a surfactant, and methods and uses thereof
WO2022090308A1 (en) * 2020-10-27 2022-05-05 Agriculture And Food Development Authority (Teagasc) Antihypertensive food ingredients for companion animal applications

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5698694A (en) * 1996-10-25 1997-12-16 Sandoz Ltd. Process for preparing substituted pyrimidines
US20050137247A1 (en) * 2003-12-22 2005-06-23 The Brigham And Women's Hospital, Inc. Methods and compositions for treatment of hypertension

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5698694A (en) * 1996-10-25 1997-12-16 Sandoz Ltd. Process for preparing substituted pyrimidines
US20050137247A1 (en) * 2003-12-22 2005-06-23 The Brigham And Women's Hospital, Inc. Methods and compositions for treatment of hypertension

Also Published As

Publication number Publication date
JP2009544702A (en) 2009-12-17
EP2049098A2 (en) 2009-04-22
WO2008011179A2 (en) 2008-01-24

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