WO2008007359A3 - Rapid diagnostic devices based on molecular imprinted polymers - Google Patents

Rapid diagnostic devices based on molecular imprinted polymers Download PDF

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Publication number
WO2008007359A3
WO2008007359A3 PCT/IL2007/000851 IL2007000851W WO2008007359A3 WO 2008007359 A3 WO2008007359 A3 WO 2008007359A3 IL 2007000851 W IL2007000851 W IL 2007000851W WO 2008007359 A3 WO2008007359 A3 WO 2008007359A3
Authority
WO
WIPO (PCT)
Prior art keywords
imprinted polymers
devices based
diagnostic devices
rapid diagnostic
molecular imprinted
Prior art date
Application number
PCT/IL2007/000851
Other languages
French (fr)
Other versions
WO2008007359A2 (en
Inventor
Raphael Levi
Ido Margalit
Yarden Dloomy
Original Assignee
Infigo Diagnostics Ltd
Raphael Levi
Ido Margalit
Yarden Dloomy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Infigo Diagnostics Ltd, Raphael Levi, Ido Margalit, Yarden Dloomy filed Critical Infigo Diagnostics Ltd
Priority to EP07766881A priority Critical patent/EP2041567A4/en
Publication of WO2008007359A2 publication Critical patent/WO2008007359A2/en
Priority to IL196223A priority patent/IL196223A0/en
Publication of WO2008007359A3 publication Critical patent/WO2008007359A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G01N33/54387—Immunochromatographic test strips
    • G01N33/54388—Immunochromatographic test strips based on lateral flow
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G01N33/54387—Immunochromatographic test strips
    • G01N33/54391—Immunochromatographic test strips based on vertical flow

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The invention pertains generally to sensitive diagnostic assay devices, methods and kits for determining the presence, absence and/or amount of analytes in fluid samples The devices (figures 3a & 3b) are based on molecularly imprinted polymers (MlPs) for use in real¬ time measurements of levels of analytes, particularly small molecules, in fluid samples One such device is a device for determination of B12 (cobalamin) deficiency or methylmalonic aciduria by measuring methylmalonic acid (MVA) in either blood or urine.
PCT/IL2007/000851 2006-07-09 2007-07-08 Rapid diagnostic devices based on molecular imprinted polymers WO2008007359A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP07766881A EP2041567A4 (en) 2006-07-09 2007-07-08 Rapid diagnostic devices based on molecular imprinted polymers
IL196223A IL196223A0 (en) 2006-07-09 2008-12-25 Rapid diagnostic devices based on molecular imprinted polymers

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80678306P 2006-07-09 2006-07-09
US60/806,783 2006-07-09

Publications (2)

Publication Number Publication Date
WO2008007359A2 WO2008007359A2 (en) 2008-01-17
WO2008007359A3 true WO2008007359A3 (en) 2009-05-07

Family

ID=38923664

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2007/000851 WO2008007359A2 (en) 2006-07-09 2007-07-08 Rapid diagnostic devices based on molecular imprinted polymers

Country Status (2)

Country Link
EP (1) EP2041567A4 (en)
WO (1) WO2008007359A2 (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101945990A (en) * 2007-12-27 2011-01-12 尹菲戈诊断有限公司 Small molecules and protein analysis devices based on molecular imprinted polymers
CN101591412B (en) * 2009-06-03 2011-05-18 中国农业科学院农业质量标准与检测技术研究所 Method for preparing chloramphenicol molecularly imprinted polymeric microspheres
WO2011010304A2 (en) * 2009-07-23 2011-01-27 Infigo Diagnostics Ltd. Method for preparing molecularly imprinted polymers and uses thereof
US9429536B2 (en) 2010-09-10 2016-08-30 Trustees Of Dartmouth College Airborne contaminant sensor device and method for using the same
WO2012034115A1 (en) * 2010-09-10 2012-03-15 Trustees Of Dartmouth College Airborne contaminant sensor device and method for using the same
US11366077B2 (en) 2010-09-10 2022-06-21 The Trustees Of Dartmouth College Systems, sensing devices and methods for detection of airborne contaminants
US10451598B2 (en) 2010-09-10 2019-10-22 The Trustees Of Dartmouth College Devices for detecting airborne contaminants, and associated methods
CN102478575A (en) * 2010-11-29 2012-05-30 内蒙古蒙牛乳业（集团）股份有限公司 Method for evaluating effectiveness of kanamycin test paper in detection of dairy products
CN102478574A (en) * 2010-11-29 2012-05-30 内蒙古蒙牛乳业（集团）股份有限公司 Method for evaluating effectivity of streptomycin test strip in detection of dairy products
US9228988B2 (en) 2011-08-31 2016-01-05 The Trustees Of Dartmouth College Molecularly imprinted polymers for detection of contaminants
CN102331503A (en) * 2011-08-31 2012-01-25 内蒙古科慧生物科技有限责任公司 Quantitative testosterone (T) measurement kit and detection method thereof
CN102426251A (en) * 2011-08-31 2012-04-25 内蒙古科慧生物科技有限责任公司 Quantitative detection kit for progesterone (P), and detection method thereof
CN102393448B (en) * 2011-10-20 2015-06-03 东北大学 Method for selectively and quantitatively collecting Cd in water environment
CN102507261B (en) * 2011-10-20 2015-06-03 东北大学 Method for selectively and quantitatively collecting arsenic in water environment
CN102520193B (en) * 2011-12-29 2014-08-13 深圳康美生物科技股份有限公司 Fluorescence immunochromatographic assay and kit for quantitative detection of human cardiac troponin I (cTnI)
AU2014412015B2 (en) * 2014-11-20 2018-08-16 Monolythix, Inc. Monoliths
US9464969B2 (en) 2014-11-20 2016-10-11 Monolythix, Inc. Monoliths
US9782771B2 (en) 2015-01-16 2017-10-10 Xerox Corporation Method for making hydrophobic barriers requiring UV-light treatment
US10570439B2 (en) 2015-08-18 2020-02-25 Monolythix, Inc. Sample concentration devices
US20170172946A1 (en) * 2015-12-21 2017-06-22 Stephan Hau Micro-solid phase extraction
CN108107223A (en) * 2016-11-24 2018-06-01 温州科技职业学院 Detect method and its enzyme linked immunological kit used of estradiol and/or oestradiol benzoate
DE102017129476B4 (en) * 2017-12-11 2024-04-18 Bundesrepublik Deutschland, vertreten durch die Bundesministerin für Wirtschaft und Energie, diese vertreten durch den Präsidenten der Bundesanstalt für Materialforschung und-prüfung (BAM) Label-free optical detection in capture zones immobilized on strips for lateral flow assays
CN112485430B (en) * 2020-11-13 2023-08-11 北京勤邦科技股份有限公司 Application of alachlor artificial antigen in ELISA kit
CN114689847B (en) * 2022-03-07 2023-07-18 西南大学 Novel lateral flow chromatography test strip based on molecular imprinting, preparation method and application thereof in detection of small molecular substance thiodiglycol

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5573921A (en) * 1992-09-04 1996-11-12 Dragerwerk Aktiengesellschaft Immunochemical displacement for determining an analyte
US5786220A (en) * 1995-04-28 1998-07-28 Quidel Corporation Assays and devices for distinguishing between normal and abnormal pregnancy
US6660176B2 (en) * 2001-01-24 2003-12-09 Virginia Commonwealth University Molecular imprinting of small particles, and production of small particles from solid state reactants

Family Cites Families (4)

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EP0462376B1 (en) * 1990-05-09 1996-07-24 Abbott Laboratories Conjugate recovery binding assays
US5874216A (en) * 1996-02-23 1999-02-23 Ensys Environmental Products, Inc. Indirect label assay device for detecting small molecules and method of use thereof
US6255051B1 (en) * 1997-11-06 2001-07-03 Mosaic Technologies Inc. Multiple sequential polynucleotide displacement reactions for signal amplification and processing
SE0001877D0 (en) * 2000-05-22 2000-05-22 Klaus Mosbach Molecular imprinting

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5573921A (en) * 1992-09-04 1996-11-12 Dragerwerk Aktiengesellschaft Immunochemical displacement for determining an analyte
US5786220A (en) * 1995-04-28 1998-07-28 Quidel Corporation Assays and devices for distinguishing between normal and abnormal pregnancy
US6660176B2 (en) * 2001-01-24 2003-12-09 Virginia Commonwealth University Molecular imprinting of small particles, and production of small particles from solid state reactants

Also Published As

Publication number Publication date
WO2008007359A2 (en) 2008-01-17
EP2041567A2 (en) 2009-04-01
EP2041567A4 (en) 2011-04-13

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