WO2008005752A3 - Modification des surfaces d'articles polymères par réaction d'addition de michael - Google Patents

Modification des surfaces d'articles polymères par réaction d'addition de michael Download PDF

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Publication number
WO2008005752A3
WO2008005752A3 PCT/US2007/072119 US2007072119W WO2008005752A3 WO 2008005752 A3 WO2008005752 A3 WO 2008005752A3 US 2007072119 W US2007072119 W US 2007072119W WO 2008005752 A3 WO2008005752 A3 WO 2008005752A3
Authority
WO
WIPO (PCT)
Prior art keywords
addition reaction
michael addition
medical device
coating polymer
modification
Prior art date
Application number
PCT/US2007/072119
Other languages
English (en)
Other versions
WO2008005752A2 (fr
Inventor
Joseph C Salamone
Wenyan Yan
Yu-Chin Lai
Weihong Lang
Original Assignee
Bausch & Lomb
Joseph C Salamone
Wenyan Yan
Yu-Chin Lai
Weihong Lang
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/479,227 external-priority patent/US20080003252A1/en
Priority claimed from US11/480,243 external-priority patent/US20080003259A1/en
Application filed by Bausch & Lomb, Joseph C Salamone, Wenyan Yan, Yu-Chin Lai, Weihong Lang filed Critical Bausch & Lomb
Priority to EP07812327A priority Critical patent/EP2035050A2/fr
Publication of WO2008005752A2 publication Critical patent/WO2008005752A2/fr
Publication of WO2008005752A3 publication Critical patent/WO2008005752A3/fr

Links

Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
    • G02B1/041—Lenses
    • G02B1/043—Contact lenses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/18—Modification of implant surfaces in order to improve biocompatibility, cell growth, fixation of biomolecules, e.g. plasma treatment

Landscapes

  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Materials For Medical Uses (AREA)

Abstract

La présente invention concerne un appareil médical comprenant une qualité d'hydrophilie de surface améliorée qui comprend un enduit polymère comportant des unités de composé hydrophilique polymérisable qui est joint à la surface du dispositif médical par le biais d'une réaction d'addition de Michael. L'enduit polymère peut être appliqué à un dispositif médical comprenant un hydrogel. L'adhésion de l'enduit polymère peut être améliorée en augmentant la population des groupes fonctionnels de surface du dispositif médical avant de d'appliquer l'enduit polymère à ce dispositif.
PCT/US2007/072119 2006-06-30 2007-06-26 Modification des surfaces d'articles polymères par réaction d'addition de michael WO2008005752A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP07812327A EP2035050A2 (fr) 2006-06-30 2007-06-26 Modification des surfaces d'articles polymères par réaction d'addition de michael

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US11/479,227 US20080003252A1 (en) 2006-06-30 2006-06-30 Functionalized hydrophilic macromonomers and medical devices incorporating same
US11/480,243 2006-06-30
US11/479,227 2006-06-30
US11/480,243 US20080003259A1 (en) 2006-06-30 2006-06-30 Modification of surfaces of polymeric articles by Michael addition reaction

Publications (2)

Publication Number Publication Date
WO2008005752A2 WO2008005752A2 (fr) 2008-01-10
WO2008005752A3 true WO2008005752A3 (fr) 2008-09-18

Family

ID=38669223

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/072119 WO2008005752A2 (fr) 2006-06-30 2007-06-26 Modification des surfaces d'articles polymères par réaction d'addition de michael

Country Status (2)

Country Link
EP (1) EP2035050A2 (fr)
WO (1) WO2008005752A2 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2010215931A1 (en) 2009-02-21 2011-10-13 Covidien Lp Medical devices having activated surfaces
US9486311B2 (en) 2013-02-14 2016-11-08 Shifamed Holdings, Llc Hydrophilic AIOL with bonding
US9250357B2 (en) 2013-03-15 2016-02-02 Johnson & Johnson Vision Care, Inc. Silicone-containing contact lens having reduced amount of silicon on the surface
BR112015024156A2 (pt) 2013-03-21 2017-07-18 Shifamed Holdings Llc lente intraocular de acomodação
US10195018B2 (en) 2013-03-21 2019-02-05 Shifamed Holdings, Llc Accommodating intraocular lens
CA3008944C (fr) 2014-08-26 2021-11-16 Shifamed Holdings, Llc Lentille intraoculaire adaptative
US11141263B2 (en) 2015-11-18 2021-10-12 Shifamed Holdings, Llc Multi-piece accommodating intraocular lens
US10350056B2 (en) 2016-12-23 2019-07-16 Shifamed Holdings, Llc Multi-piece accommodating intraocular lenses and methods for making and using same
AU2018277037B2 (en) 2017-05-30 2024-04-18 Shifamed Holdings, Llc Surface treatments for accommodating intraocular lenses and associated methods and devices
US11266496B2 (en) 2017-06-07 2022-03-08 Shifamed Holdings, Llc Adjustable optical power intraocular lenses
BR112020019262B1 (pt) 2018-03-27 2023-12-12 Mercene Coatings Ab Método de revestimento de um substrato e substrato revestido
CN116635492A (zh) * 2020-12-30 2023-08-22 康沃特克科技公司 医疗器材的官能化

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000072052A1 (fr) * 1999-05-20 2000-11-30 Bausch & Lomb Incorporated Traitement de surface de dispositifs medicaux a l'aide de polymere hydrophiles reactifs
US20020120333A1 (en) * 2001-01-31 2002-08-29 Keogh James R. Method for coating medical device surfaces
WO2003063926A1 (fr) * 2002-02-01 2003-08-07 Sustech Gmbh & Co. Kg Prepolymeres en etoile pour la production de revetements ultraminces formant des hydrogels
WO2005102675A2 (fr) * 2004-04-21 2005-11-03 Novartis Ag Encres colorees sechables destinees a la fabrication de lentilles colorees en silicone hydrogel

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000072052A1 (fr) * 1999-05-20 2000-11-30 Bausch & Lomb Incorporated Traitement de surface de dispositifs medicaux a l'aide de polymere hydrophiles reactifs
US20020120333A1 (en) * 2001-01-31 2002-08-29 Keogh James R. Method for coating medical device surfaces
WO2003063926A1 (fr) * 2002-02-01 2003-08-07 Sustech Gmbh & Co. Kg Prepolymeres en etoile pour la production de revetements ultraminces formant des hydrogels
WO2005102675A2 (fr) * 2004-04-21 2005-11-03 Novartis Ag Encres colorees sechables destinees a la fabrication de lentilles colorees en silicone hydrogel

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
HEGGLI M. ET AL: "Michael-type addition as a tool for surface functionalization", BIOCONJUGATE CHEM., vol. 14, 2003, pages 967 - 973, XP002485565 *

Also Published As

Publication number Publication date
EP2035050A2 (fr) 2009-03-18
WO2008005752A2 (fr) 2008-01-10

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