WO2008004224A3 - Synergistic compositions for crohn's disease and inflammatory gastrointestinal disorders - Google Patents

Synergistic compositions for crohn's disease and inflammatory gastrointestinal disorders Download PDF

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Publication number
WO2008004224A3
WO2008004224A3 PCT/IL2007/000828 IL2007000828W WO2008004224A3 WO 2008004224 A3 WO2008004224 A3 WO 2008004224A3 IL 2007000828 W IL2007000828 W IL 2007000828W WO 2008004224 A3 WO2008004224 A3 WO 2008004224A3
Authority
WO
WIPO (PCT)
Prior art keywords
disease
gastrointestinal disorders
crohn
synergistic compositions
inflammatory gastrointestinal
Prior art date
Application number
PCT/IL2007/000828
Other languages
French (fr)
Other versions
WO2008004224A2 (en
Inventor
Arie Levine
Original Assignee
Arie Levine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arie Levine filed Critical Arie Levine
Publication of WO2008004224A2 publication Critical patent/WO2008004224A2/en
Publication of WO2008004224A3 publication Critical patent/WO2008004224A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention relates to methods and synergistic compositions comprising a nitroimidazole antibiotic and a macrolide antibiotic, optionally in combination with polyphenolic compounds naturally contained in plant or fruit, for treatment of chronic inflammatory gastrointestinal disorders including Crohn's disease.
PCT/IL2007/000828 2006-07-03 2007-07-03 Synergistic compositions for crohn's disease and inflammatory gastrointestinal disorders WO2008004224A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81769106P 2006-07-03 2006-07-03
US60/817,691 2006-07-03

Publications (2)

Publication Number Publication Date
WO2008004224A2 WO2008004224A2 (en) 2008-01-10
WO2008004224A3 true WO2008004224A3 (en) 2009-04-09

Family

ID=38894986

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2007/000828 WO2008004224A2 (en) 2006-07-03 2007-07-03 Synergistic compositions for crohn's disease and inflammatory gastrointestinal disorders

Country Status (1)

Country Link
WO (1) WO2008004224A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108135982A (en) * 2015-06-16 2018-06-08 默多克儿童研究所 The method for treating Crohn disease

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1991270A4 (en) 2005-12-22 2009-12-02 Anaborex Inc Compositions and methods for prevention and treatment of cachexia
US7947579B2 (en) * 2006-02-13 2011-05-24 Stc.Unm Method of making dense, conformal, ultra-thin cap layers for nanoporous low-k ILD by plasma assisted atomic layer deposition
EP2135616B1 (en) * 2008-06-19 2016-05-04 Symrise AG Dried bilberries for influencing intestinal conditions
CA2832059C (en) * 2011-04-01 2020-07-14 Ocean Spray Cranberries, Inc. Inflammation and immunity treatments
CN103142494B (en) * 2013-03-19 2018-06-26 河北凯盛医药科技有限公司 Ornidazole oral preparation and preparation method thereof
EP3244890A4 (en) * 2014-12-20 2018-11-21 Gregg, John Malcolm Hall Antimicrobial drug synthesis and therapeutic compositions
EP3768262A4 (en) * 2018-03-23 2021-12-15 Thomas Julius Borody Compositions and methods for treating inflammatory bowel disease and fusobacteria-caused or related diseases and conditions

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5599795A (en) * 1994-08-19 1997-02-04 Mccann; Michael Method for treatment of idiopathic inflammatory bowel disease (IIBD)
US6219997B1 (en) * 1996-07-01 2001-04-24 Astrazeneca Ab Blister pack
US6379651B1 (en) * 1995-02-07 2002-04-30 Josman Laboratories Oral-topical dosage forms for delivering antibacterials/antibiotics to oral cavity to eradicate H. pylori as a concomitant treatment for peptic ulcers and other gastro-intestinal diseases

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5599795A (en) * 1994-08-19 1997-02-04 Mccann; Michael Method for treatment of idiopathic inflammatory bowel disease (IIBD)
US6379651B1 (en) * 1995-02-07 2002-04-30 Josman Laboratories Oral-topical dosage forms for delivering antibacterials/antibiotics to oral cavity to eradicate H. pylori as a concomitant treatment for peptic ulcers and other gastro-intestinal diseases
US6219997B1 (en) * 1996-07-01 2001-04-24 Astrazeneca Ab Blister pack

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE MEDLINE accession no. STN Database accession no. 10749316 *
HULTEN ET AL: "Antibacterial Therapy for Crohn's disease: a review emphasizing therapy directed against mycobacteria", DIGESTIVE DISEASES AND SC, vol. 45, no. 3, March 2000 (2000-03-01), XP002394153, DOI: doi:10.1023/A:1005453409445 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108135982A (en) * 2015-06-16 2018-06-08 默多克儿童研究所 The method for treating Crohn disease

Also Published As

Publication number Publication date
WO2008004224A2 (en) 2008-01-10

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