WO2008002609A3 - Hydroquinone compositions for skin lightening - Google Patents

Hydroquinone compositions for skin lightening Download PDF

Info

Publication number
WO2008002609A3
WO2008002609A3 PCT/US2007/014910 US2007014910W WO2008002609A3 WO 2008002609 A3 WO2008002609 A3 WO 2008002609A3 US 2007014910 W US2007014910 W US 2007014910W WO 2008002609 A3 WO2008002609 A3 WO 2008002609A3
Authority
WO
WIPO (PCT)
Prior art keywords
compositions
skin
skin lightening
hydroquinone
lightening
Prior art date
Application number
PCT/US2007/014910
Other languages
French (fr)
Other versions
WO2008002609A2 (en
Inventor
Daniel B Yarosh
Kimberly Burch
Original Assignee
Applied Genetics Inc Dermatics
Daniel B Yarosh
Kimberly Burch
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Genetics Inc Dermatics, Daniel B Yarosh, Kimberly Burch filed Critical Applied Genetics Inc Dermatics
Publication of WO2008002609A2 publication Critical patent/WO2008002609A2/en
Publication of WO2008002609A3 publication Critical patent/WO2008002609A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/347—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66—Enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/004—Aftersun preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Cosmetics (AREA)

Abstract

Compositions for lightening skin color (or for reducing skin darkening) and for repairing DNA damage are provided. The compositions comprise (a) one or more skin lightening agents (e.g., hydroquinone) in a combined amount effective to lighten skin (or to reduce darkening), (b) one or more DNA repair agents (e.g., one or more DNA repair enzymes in pH-sensitive liposomes) in a combined amount effective to repair DNA damage by ultraviolet light, and (c) a cosmetically or pharmaceutically acceptable vehicle. Methods for preparing and using the compositions are also provided.
PCT/US2007/014910 2006-06-28 2007-06-27 Hydroquinone compositions for skin lightening WO2008002609A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81719406P 2006-06-28 2006-06-28
US60/817,194 2006-06-28

Publications (2)

Publication Number Publication Date
WO2008002609A2 WO2008002609A2 (en) 2008-01-03
WO2008002609A3 true WO2008002609A3 (en) 2008-07-24

Family

ID=38846293

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/014910 WO2008002609A2 (en) 2006-06-28 2007-06-27 Hydroquinone compositions for skin lightening

Country Status (1)

Country Link
WO (1) WO2008002609A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120230930A1 (en) * 2011-03-08 2012-09-13 Corstjens Hugo A Methods For Activating Caspase-14 Expression In Human Skin
EP2701679A4 (en) * 2011-04-29 2014-12-31 Photomedex Inc Topical dna repair compositions

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4835191A (en) * 1984-05-01 1989-05-30 Biegeleisen Ken P Methods for prevention of post-inflammatory hyperpigmentation
US6274124B1 (en) * 1999-08-20 2001-08-14 Dragoco Gerberding & Co. Ag Additive for improving the water resistance of cosmetic or dermatological formulations
US6479533B1 (en) * 1997-02-20 2002-11-12 Applied Genetics Incorporated Dermatics Methods and compositions for the protection of mitochondria
US20050042233A1 (en) * 2003-08-21 2005-02-24 Christopher Marrs Stabilized compositions containing an oxygen-labile active agent and a fungal extract

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4835191A (en) * 1984-05-01 1989-05-30 Biegeleisen Ken P Methods for prevention of post-inflammatory hyperpigmentation
US6479533B1 (en) * 1997-02-20 2002-11-12 Applied Genetics Incorporated Dermatics Methods and compositions for the protection of mitochondria
US6274124B1 (en) * 1999-08-20 2001-08-14 Dragoco Gerberding & Co. Ag Additive for improving the water resistance of cosmetic or dermatological formulations
US20050042233A1 (en) * 2003-08-21 2005-02-24 Christopher Marrs Stabilized compositions containing an oxygen-labile active agent and a fungal extract

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
YAROSH ET AL.: "Anti Inflammatory activity in skin by biomimetic of Evodia rutaecarpa extract from traditional Chinese medicine", J DERMATOLOGICAL SCI., vol. 42, 2006, pages 13 - 21, XP025100922, DOI: doi:10.1016/j.jdermsci.2005.12.009 *
YAROSH: "Liposomes in Investigative Dermatology", PHOTODERMATOLOGY PHOTOIMMUNOLOGY & PHOTOMEDICINE, vol. 17, 2001, pages 203 - 212, XP009005257, DOI: doi:10.1034/j.1600-0781.2001.170501.x *

Also Published As

Publication number Publication date
WO2008002609A2 (en) 2008-01-03

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