WO2008001820A1

WO2008001820A1 - Agent for prevention of leakage of body fluid from dead body

Info

Publication number: WO2008001820A1
Application number: PCT/JP2007/062934
Authority: WO
Inventors: Tatsuya Doi
Original assignee: St Kikaku Ltd.
Priority date: 2006-06-30
Filing date: 2007-06-27
Publication date: 2008-01-03
Also published as: JP4081498B2; TW200808173A; JP2008007485A

Abstract

An agent for preventing the leakage of a body fluid, comprising a viscous base solution comprising (A) at least one solvent selected from the group consisting of a hydrophilic ether and a hydrophilic ether, (B) at least one dispersion-stabilizer selected from the group consisting of a polyalkyleneoxide-type thermoplastic nonionic water-absorbable resin, a carboxyvinyl polymer (which is a polymer of acrylic acid), a carboxyvinyl polymer (which is a polymer of acrylic acid)/an alkali-neutralizing agent, lipophilic smectite, synthetic hectorite, natural hectorite and bentonite, and/or (C) a thickening agent such as an urethane resin, polyvinyl ether, ethyl cellulose and polyethylene oxide and (D) a highly water-absorbable resin powder dispersed in the viscous base solution. The agent can be injected and filled into a body cavity of a dead body with an injection tool. When the agent contacts with a body fluid in the body cavity, the agent absorbs the body fluid rapidly, and then swells and is solidified.

Description

Specification

Body fluid leakage prevention agent

Technical field

[0001] The present invention relates to an oil jelly-like body fluid leakage prevention for preventing fluid leakage from a corpse by loading and sealing the body cavity such as mouth, nose, ear, anus, and female vagina. Concerning agents.

Background art

[0002] In general, after the death of a human animal, muscles in various parts of the body cavity relax, and body fluids such as gastric fluid, lung fluid, ascites, and excreta are often leaked, which is also a cause of infection by pathogenic bacteria. ing. For this reason, for example, in hospitals, after confirming death, body cavities such as the mouth, nose, ears, anus, and woman's vagina are loaded with a large amount of gauze, cotton wool, etc. to prevent leakage of bodily fluids. Similar measures are also taken for the opening of the body after an accident or surgery. However, many of the operations for loading gauze and cotton wool into body cavities are often carried out by the hands of employees and nurses. Due to the low water absorption capacity, there was a problem that body fluids often leaked during or after work, and there was a possibility of postmortem infection due to this leaked substance during work, and there was a strong need for a solution.

[0003] It is known that superabsorbent resin powder is loaded into the mouth, nose, ears, throat, etc. instead of such force, gauze, absorbent cotton, etc., for example, using a syringe. In addition, a method of loading a superabsorbent resin powder into the nose and ears (see Patent Document 1), or a water-absorbent resin powder containing stabilized chlorine dioxide is used as a powder in the throat and a water-soluble sheet in the ear and nostrils. A method of wrapping and using is known (see Patent Document 2). However, even when trying to load such a high water-absorbent resin powder with a force S, it is difficult to load into narrow body cavities such as the throat and anus because of poor fluidity. Moreover, if it is only the entrance part of a nostril or an ear canal, the force S which can be filled with such a fine powder with an injector such as a syringe cannot be filled to the back. In addition, if you try to fill the syringe with power to fill it all the way, the fine powder coming out from the tip will scatter and only dirty around the body. [0004] In order to solve such problems as filling properties and poor workability of such a superabsorbent resin powder and scattering, it has recently been proposed to use a jelly made of powder. A method of using a powder polymer containing a deodorant dissolved in an appropriate amount of water and mixing it appropriately to form a jelly (see Patent Document 3), or an amphiphilic gel based on dimethylacrylamide There are known methods (see Patent Document 4), and methods using a high-absorbent polymer powder dispersed in a jelly mainly composed of alcohol (see Patent Document 5).

[0005] A filling method for filling such a jelly-like body fluid leakage preventing agent in, for example, the throat of the nostril will be described with reference to FIG. Injector 1 containing body fluid leakage preventive agent 2 has piston 3 slidably inserted from its rear end! /, And has an inlet 4 with a protective cap 5 on its tip. The film pack (not shown) is wrapped and sealed. The insertion tube 6 to be inserted into a body cavity such as the throat part B has a connection part 7 connected to the injection port 4 of the injector 1 at one end and an opening part 8 inserted into the nostril A at the other end. Have.

[0006] Next, a method of using the corpse treatment apparatus prepared in this way will be described. In Fig. 1, A is the nostril, B is the throat, C is the tongue, D is the trachea, and E is the esophagus. When using, remove the injector 1 from the film pack, remove the protective cap 5 from the inlet 4 of the injector 1, fit the connecting portion 7 of the inlet pipe 6 into the inlet 4, and connect the inlet pipe 6. Next, the opening 8 of the insertion tube 6 is inserted from the nostril A toward the throat B, and the insertion is stopped when the stopper portion 9 of the insertion tube 6 hits the nose tip B. Then, the piston 3 of the injector 1 is pressed, and the jelly-like body fluid leakage preventing agent 2 in the injector 1 is injected into the throat B through the insertion tube 6. After extruding and filling the fluid leakage preventive agent 2 in the injector 1, remove the injector 1 and the insertion tube 6 from the nostril A.

[0007] The jelly-like body fluid leakage preventing agent as described above has an advantage that even if it is a narrow body cavity such as a nostril or an ear hole having high fluidity, it will not be scattered even if it is press-fitted with an injectable syringe. Have In particular, in the case of a jelly in which a large number of highly water-absorbing polymer powders are dispersed, the water-absorbing performance is high, and it is possible to prevent the polymer from absorbing body fluid leaking from the body cavity and leaking to the outside. However, the conventional jelly-like fluid leakage preventive agent is made by adding a gelling agent to water or alcohol to make it into a jelly form. Therefore, there is a problem that the body fluid tends to leak due to the relaxation of muscles in each part of the body cavity after death. In addition, it cannot be said that it is sufficient in terms of the ability to absorb liquid immediately after injection into the body cavity, and there is room for improvement in terms of the stability of stably maintaining the jelly for a long period of time.

Patent Document 1: JP-A-10-298001

Patent Document 2: Japanese Patent Laid-Open No. 7-265367

Patent Document 3: Japanese Patent Laid-Open No. 8-133901

Patent Document 4: Japanese Patent Laid-Open No. 2001-288002

Patent Document 5: Japanese Patent No. 3586207

Disclosure of the invention

Problems to be solved by the invention

[0008] Therefore, the basic object of the present invention is to inject and load a body cavity of a corpse with an injection device, and when it comes into contact with body fluid in the body cavity, it quickly absorbs and swells and solidifies, effectively preventing body fluid leakage. It is intended to provide a body fluid leakage preventive agent that can be prevented.

Furthermore, the object of the present invention is to easily prepare a jelly with appropriate fluidity and viscoelasticity that can be injected and loaded with good workability into the body cavity of the corpse, and can maintain its state stably. Is to provide.

Means for solving the problem

In order to achieve the above object, according to the present invention, at least one solvent (A) selected from the group consisting of a hydrophilic ether and an ester, and a polyalkylene oxide-based thermoplastic resin are used. 2-ion type water-absorbing resin (nonionic thermoplastic / water-absorbing resin having polyalkylene oxide group), carboxybule polymer that is a polymer of acrylic acid, carboxybule polymer that is a polymer of attalinoleic acid / alkali neutralization Group power consisting of an agent (alkali salt of carboxyvinyl polymer), lipophilic smectite, synthetic hectorite, natural hectorite, and bentonite Selected at least one dispersion stabilizer (B) and / or thickener There is provided a body fluid leakage preventing agent characterized in that the superabsorbent resin powder (D) is dispersed in a viscous liquid base containing (C).

[0010] In a preferred embodiment! /, The solvent (A) comprises polyoxyethylene dimethyl ether and polyoxyethylene dimethyl ether. And at least one selected from the group consisting of polyoxyethylene fatty acid diesters

Yes

In another preferred embodiment, the dispersion stabilizer (B) is a polyalkylene oxide thermoplastic noion-type water-absorbing resin.

In still another preferred embodiment, the thickener (C) is at least one selected from the group consisting of urethane resin, polybutyl ether, ethyl cellulose and polyethylene oxide.

In a particularly preferred embodiment, a polyalkylene oxide-based thermoplastic nonionic water-absorbing resin as the dispersion stabilizer (B), a urethane resin, a polybutylmethyl ether, and an ethoxy group of 45-50 are used. A mixed system of at least one thickener (C) of ethylcellulose and polyethylene oxide containing 1% is used.

The body fluid leakage preventive agent of the present invention is at least one selected from the group consisting of a liquid noionic surfactant (E) that generates heat when mixed with water and an alcohol-based organic solvent (F) soluble in water. It can also contain seeds, and can also contain at least one selected from the group consisting of bactericides, fungicides, preservatives, deodorants and fragrances.

The invention's effect

[0011] The body fluid leakage preventive agent of the present invention comprises at least one solvent (A) selected from the group consisting of hydrophilic ethers and esters, and a polyalkylene oxide thermoplastic nonionic water-absorbing property. Resin, carboxybule polymer that is a polymer of acrylic acid, carboxybule polymer that is a polymer of acrylic acid / alkali neutralizer (alkali salt of carboxyvinyl polymer), lipophilic smectite, synthetic hectorite, natural hectorite And at least one dispersion stabilizer (B) selected from the group consisting of bentonite and / or a thickener (C) such as urethane resin, polybutyl ether, ethyl cellulose, and polyethylene oxide. Since it is an oil jelly-like material in which a superabsorbent resin powder (D) is dispersed in a viscous liquid base, it is injected into the body cavity of an corpse with an injection device. However, when it comes into contact with bodily fluids in the body cavity, it quickly absorbs and swells and solidifies into a solid jelly (solid gel) with no fluidity, thereby effectively preventing bodily fluid leakage. it can.

[0012] Further, according to a preferred aspect of the bodily fluid leakage preventing agent of the present invention, the solvent (A) contains Group power consisting of xylethylene dimethyl ether and polyoxyethylene fatty acid diester. Because it is at least one selected, it can be easily injected into the body cavity of the corpse with good workability and can easily be put into a jelly with fluidity and viscoelasticity. The dispersion stabilizer can be prepared

(B) a polyalkylene oxide-based thermoplastic nonionic water-absorbing resin, and at least selected from the group consisting of urethane resin, polybutyl ether, ethyl cellulose and polyethylene oxide as the thickener (C). Since it is a mixed system with one kind, it is possible to more reliably maintain a uniform dispersion state of the superabsorbent resin powder (D) when in contact with a body fluid. Therefore, the superabsorbent resin powder (D) is dispersed in a viscous liquid base containing a combination of the solvent (A) and the dispersion stabilizer (B) and / or the thickener (C). The body fluid leakage prevention agent can be injected and loaded into the body cavity of the corpse with good workability and can maintain a stable jelly-like state with adequate fluidity and viscoelasticity, and when injected into the body cavity of the corpse, Absorbs and swells bodily fluids as a whole and solidifies into a solid jelly with no fluidity, making it possible to more effectively prevent bodily fluid leakage.

[0013] The body fluid leakage preventive agent of the present invention further includes, as auxiliary solvents, a liquid noion surfactant (E) that generates heat when mixed with water, and an alcohol-based organic solvent (F) soluble in water. By containing at least one kind, viscosity adjustment can be facilitated and fluidity can be improved, and even a narrow body cavity such as the throat can be injected and loaded more smoothly. In particular, when it contains a liquid noionic surfactant (E) that is rapidly soluble in water when mixed with water, the exothermic surfactant (E) generates heat when it comes into contact with body fluids. In addition, the liquid absorption speed of the highly water-absorbent resin powder (D) can be increased. Furthermore, by containing at least one selected from the group consisting of bactericides, antibacterial agents, antiseptics, deodorants, and fragrances, these desired effects can also be exhibited.

Brief Description of Drawings

FIG. 1 is a schematic cross-sectional view showing a use state of a conventional corpse treatment apparatus.

FIG. 2 shows one embodiment of a corpse treatment apparatus suitable for injection of the bodily fluid leakage preventing agent of the present invention.

(A) is a front view, (B) is a left side view, and (C) is a right side view.

3 is a longitudinal sectional view taken along the central axis of the body treatment apparatus shown in FIG.

4 is a cross-sectional view taken along the central axis of the corpse treatment apparatus shown in FIG. FIG. 5 is a longitudinal sectional view showing an insertion tube of a corpse treatment apparatus suitable for injecting the bodily fluid leakage preventing agent of the present invention.

FIG. 6 shows another embodiment of a corpse treatment apparatus suitable for injection of the bodily fluid leakage preventing agent of the present invention, (A) is a front view, (B) is a left side view, and (C) is a right side view. It is.

7] FIG. 7 is a longitudinal sectional view taken along the central axis of the corpse treatment apparatus shown in FIG.

Garden 8] FIG. 7 is a transverse sectional view taken along the central axis of the corpse treatment apparatus shown in FIG.

Explanation of symbols

1, 10, 10a injector

20, 20a Tubular body

21, 21a Cylindrical member

22, 22a Discharge port (discharge cylinder)

23 Locking part

24 ridge

25, 25a Cover member

26 Buttocks

27, 44 Stopper

28 Tongue

29, 29a Protective cap

30 pistons

31 Piston rod

32 Circular flange

33

34 Gasket

35 Disc-shaped part

40 Insertion tube

42 Opening

43 Connection

X Body fluid leakage prevention agent Y fibrous filler

Α Nostrils

B Throat

C tongue

D trachea

E esophagus

BEST MODE FOR CARRYING OUT THE INVENTION

[0016] As a result of intensive studies to solve the above-described conventional problems, the present inventor has at least one solvent (A) selected from the group consisting of hydrophilic ethers and esters, and a solution thereof. Oil jelly-like body fluid leakage prevention by dispersing a superabsorbent resin powder (D) in a viscous liquid base containing the specific dispersion stabilizer (B) and / or thickener (C). The agent was found to be able to quickly absorb and swell body fluid when it was injected and loaded into the body cavity of the corpse and solidified into a solid jelly with no fluidity, resulting in the completion of the present invention. It is. The reason why such an effect is obtained is not necessarily clear, but at least one solvent (A) selected from the group consisting of hydrophilic ethers and esters is also used as a solvent for detergents. As well as being hydrophilic, it also has excellent oil and fat solubility! /, So it contains not only moisture but also fat and oil! / This is probably because of this. In addition, since it is also lipophilic, it is possible to disperse a relatively large amount of the superabsorbent resin powder (D), and the specific dispersion stabilizer (B) and / or the solvent (A) can be dispersed in such a solvent (A). The oil jelly-like body fluid leakage preventing agent of the present invention, in which the superabsorbent resin powder (D) is dispersed in the viscous liquid base in which the thickener (C) is dissolved, is also excellent in stability.

[0017] Hereinafter, each component of the bodily fluid leakage preventing agent of the present invention will be described.

First, the at least one solvent (A) selected from the group consisting of hydrophilic ethers and esters may be a liquid compound at room temperature (20 ± 5 ° C) that exhibits hydrophilicity among ethers and esters. In particular, at least one selected from the group consisting of polyoxyethylene dimethyl ether and polyoxyethylene fatty acid diesters can be suitably used. Polyoxyethylene fatty acid diesters have the general formula RCOO (CH CH O) The force represented by COR S and alkyl groups R preferably have 17 or less carbon atoms.

2 n

Examples include polyethylene glycol dilaurate and polyethylene glycol dioleate. Among these, polyoxyethylene dimethyl ether is particularly preferable. In addition, the polymerization degree of these solvents is not particularly limited as long as the polymerization degree becomes liquid at room temperature (20 ± 5 ° C.).

However, since these solvents (A) are in a smooth liquid state at room temperature, it is necessary to dissolve the dispersion stabilizer (B) and / or the thickener (C) to increase the viscosity of the composition. Do not add the dispersion stabilizer (B) and / or the thickener (C)! / In some cases, when the obtained body fluid leakage preventing agent is pressed into the body cavity by the injector, Comes out first, and the solid content easily clogs the tip of the injector, making it difficult to inject.

[0018] The content of the solvent (A) is preferably about 30 to 85% by mass, more preferably about 40 to 80% by mass, and further preferably about 50 to 70% by mass of the total amount of the body fluid leakage preventing agent. . When the content of the solvent (A) exceeds 85% by mass, there is no problem in the dispersibility of the superabsorbent resin powder, but it is not preferable because it becomes a state that is close to a jelly-like solution. . On the other hand, if the content of the solvent (A) is too low, it is difficult to obtain a good jelly state.

[0019] The dispersion stabilizer (B) used in the present invention is for maintaining a uniform dispersion state of the superabsorbent resin powder, can absorb various aqueous electrolyte solutions, and is almost affected by the electrolyte concentration. N / A, polyalkylene oxide thermoplastic nonionic water-absorbing resin, carboxybule polymer, which is a polymer of acrylic acid, carboxylic acid polymer / alkali neutralizing agent, which is a polymer of acrylic acid Alkali salt), lipophilic smectite, synthetic hectorite, natural hectorite, and bentonite are used. Among these dispersion stabilizers (B), polyalkylene oxide-based thermoplastic nonionic water-absorbing resins are preferred. These resins can absorb various electrolyte aqueous solutions and are hardly affected by the electrolyte concentration. It can absorb water and alkaline solution. However, when only this resin is used as a dispersion stabilizer, the resulting jelly-like product tends to be somewhat hard, and there is a slight difficulty in terms of slipping during injection. Alkylene oxide thermoplastic nonionic water absorption It is preferable to use a mixed system of a resin and at least one thickener (C) selected from urethane resin, polymethyl ether, ethyl cellulose containing 45 to 50% ethoxy group, and polyethylene oxide.

[0020] The content of the dispersion stabilizer (B) is preferably about 0.5 to 40% by mass, more preferably about 1 to 30% by mass, based on the total amount of the body fluid leakage preventing agent. If the content of the dispersion stabilizer (B) is too low, it becomes difficult to maintain the uniform dispersibility of the superabsorbent resin powder. On the other hand, even if it is added in a large amount exceeding 40% by mass, the effect is further improved. Is not seen and is preferable from the point of economy.

[0021] The thickener (C) is added in order to increase the viscosity of the composition to obtain a stable oil jelly-like product. The thickener (C) is not limited to a specific one, but urethane resin, polybutyl ether, ethyl cellulose, polyethylene oxide, sodium carboxymethyl cellulose, carboxymethyl cellulose, methyl cellulose, polyvinyl alcohol, polypyrrole pyrrolidone, At least one thickener selected from the group consisting of sora gum and sodium alginate can be suitably used. Among these, urethane resin, polybutyl ether, ethyl cellulose, and polyethylene oxide are preferable. The content of the thickening agent is preferably about 0.2 to 7% by mass, more preferably about 0.2 to 7% by mass, based on the total amount of the body fluid leakage preventing agent.

[0022] As the superabsorbent resin powder (D) used in the present invention, conventionally known superabsorbent resin powders can be used, and are not limited to specific ones. Atallate, polyacrylate, alginate, acrylic acid graft copolymer bridge, copolymer of butyl alcohol and polyacrylic acid, polyethylene glycol polymer, polyacrylamide resin, polyacrylic acid maleic acid copolymer At least one selected from the group consisting of a polymer, a polyethylene oxide polymer, and a polyalginate polymer can be suitably used.

[0023] The superabsorbent resin powder (D) preferably has a mean particle size of about 18 mesh to 160 mesh (according to Tyler display), more preferably about 30 mesh to 140 mesh.

In addition, the content of the superabsorbent resin powder (D) must be an amount necessary to create a non-flowable gel by immediately absorbing and expanding the body fluid without leaking from the body cavity. The content of the superabsorbent resin powder is preferably about 5 to 50% by mass of the total amount of the body fluid leakage preventing agent. More preferably, it is about 15 to 35% by mass.

[0024] The body fluid leakage preventive agent of the present invention, in addition to the above-described components, optionally generates a nonionic surfactant (E) and / or a liquid at room temperature that generates heat when mixed with water as an auxiliary solvent, if necessary. Alternatively, an alcohol-based organic solvent (F) soluble in water can be contained.

[0025] As the nooionic surfactant (E) which is exothermic when mixed with water used in the present invention and which is liquid at room temperature, coconut oil fatty acid monoethanolamide, coconut oil fatty acid diethanolamide 1: 1 type, coconut oil fatty acid diethanolamide 1: 2 type, polyoxyethylene coconut oil fatty acid monoethanolamide, lauric acid diethanolamide, polyoxyethylene lauryl ether, poly talented xylene ethylene cetino reetenole, poly talented xyethylene higher alcoholate enole, polyethylene glycol (The average molecular weight of the degree of polymerization is 600 or less), polyoxyethylene polyoxypropylene glycol (pull nick type nonionic surfactant obtained by adding ethylene oxide to polypropylene glycol), polyoxyethylene alkyl (carbon number of alkyl group) 12 ~; 14) Ether Examples of surfactants such as polyoxyethylene alkyl ethers, sorbitan fatty acid esters, and polyoxyethylene sorbitan fatty acid esters, such as the number of moles of ethylene oxide added: 7 to 12 moles, are used alone or in combination of two or more. They can be used in combination. Among these nonionic surfactants (E), liquid polyethylene glycol (average molecular weight of polymerization degree is about 200 to 600) is preferable. Strictly speaking, polyethylene glycol is a force that should be called a precursor of a nonionic surfactant. In this specification, it is classified as a noionic surfactant. However, it may be classified as an alcohol-based organic solvent (F) described later.

[0026] These liquid nonionic surfactants (E), particularly liquid polyethylene glycol (average molecular weight of the polymerization degree is about 200 to 600) can be used as a part of the solvent, and the dispersion stability described above. Agent (B), especially polyalkylene oxide-based thermoplastic nonionic water-absorbent resin powder, can be easily dissolved at low temperature (about 30 ° C to 50 ° C), and when mixed with water, As is clear from Test Example 2 described later, when it comes into contact with water, it generates heat and the water temperature rises (increases by about 10 ° C to 12 ° C). Furthermore, it is a surfactant and easily compatible with water that is compatible with water As described above, the water absorption speed of the superabsorbent resin can be increased, and the liquid can be quickly solidified into a solid jelly without fluidity to prevent leakage of bodily fluids. That is, since the water absorption rate of the highly water-absorbent resin powder (D) generally tends to increase as the temperature rises, the exothermic action of the noionic surfactant (E) when in contact with body fluids Thus, the liquid absorption rate of the superabsorbent resin powder (D) can be increased, and the body fluid can be quickly absorbed and swollen to be solidified into a solid jelly having no fluidity. However, as the liquid absorption speed increases, the surface portion of the injected jelly-like material that comes into contact with the body fluid quickly solidifies into a solid jelly with no fluidity. Uniform dispersibility tends to collapse. Further, if the obtained jelly-like body fluid leakage preventing agent is allowed to stand for a long time, it becomes easy to separate. In the bodily fluid leakage preventive agent of the present invention, the above-mentioned specific dispersion stabilizer (B) that can absorb various electrolyte aqueous solutions and is hardly affected by the electrolyte concentration is further dissolved in the viscous liquid base. Although the water-absorbent resin powder (D) has a uniform dispersibility, the content of the noionic surfactant (E) is about 50% by mass or less of the total amount of the body fluid leakage preventing agent. Is more preferably about 3 to 40% by mass, and still more preferably about 5 to 20% by mass.

[0028] The bodily fluid leakage preventive agent of the present invention contains an anionic surfactant as needed in a quantitative ratio that does not impair the effects of the present invention, in addition to the above-described noionic surfactant (E). You can also.

Examples of the anionic surfactant include polyoxyethylene alkyl ether sulfate, polyoxyethylene lauryl ether sodium sulfate, polyoxyethylene lauryl ether triethanolamine, polyoxyethylene alkyl (alkyl group having 11 to 15 carbon atoms). ) Sodium ether sulfate (Mole number of ethylene oxide added: 3) Alkyl (carbon number of alkyl group 11, 13, 15) Triethanolamine, sodium alkyl sulfate, triethanolamine alkyl sulfate, sodium higher alcohol sulfate, etc. Polyoxyethylene alkyl sulfosuccinate disodium, polyoxyethylene sulfone succinate, polyoxyethylene sulfosuccinate lauryl disodium, lauric disodium sulfonate, sulfosuccinate Surfactants such as sulfosuccinates such as reoxyethylene lauryl ethanolamido nitrile; alkylbenzene sulfonates such as sodium dodecylbenzene sulfonate, and the like are used alone or in combination of two or more. be able to. [0029] As the alcohol-based organic solvent (F), any water-soluble solvent such as the nonionic surfactant or polar solvent can be used, and is not limited to a specific solvent, but includes ethylene glycol, propylene glycol or diethylene. At least one alcohol-based organic solvent selected from the group consisting of glyconole, triethyleneglycolole, glycerin, methenoreanoleconole, ethyl alcohol, and isopropyl alcohol can be preferably used. Among these alcohol solvents, glycerin is preferable. Glycerol easily mixes with water, and slightly increases the water temperature when mixed (approximately 3 ° C). Therefore, it is possible to increase the water absorption rate of the highly water-absorbent resin, increase the viscosity of the prepared body fluid leakage preventing agent, improve the fluidity, and contribute to preventing the oil jelly from solidifying at low temperatures.

The content of the alcohol organic solvent is preferably about 20% by mass or less, more preferably about 1 to 10% by mass, based on the total amount of the body fluid leakage preventing agent.

[0030] The body fluid leakage preventing agent of the present invention may further contain at least one other additive such as a bactericidal agent, a fungicide, a preservative, a deodorant, and a fragrance, if necessary.

Disinfectants include isopropylmethylphenol, chlorhexidine dalconate, thymol, o-phenol, benzalkonium chloride, cetylpyridinium chloride, benzethonium chloride, triclosan, ε-polylysine, lysozyme chloride, hinokitiol , Drape fruit seed extract, power rashi extract “ヮ sao bite” and the like, and these can be used alone or in combination of two or more.

[0031] Antifungal 'Preservatives include sodium nonoxybenzoate, petit nore, paraoxybenzoate, propyl nonoxybenzoate, isoptyl noroxybenzoate, sodium benzoate, sodium propionate, thiabendazole, isothiazolone, etc. These can be used alone or in combination of two or more.

[0032] As a deodorant, a plant system in which a moso soda extract, a green tea extract, a long-chain betaine compound, a deodorant mainly composed of a generic type tannin of persimmon extract, and several kinds of plant extracts are mixed. Examples include special deodorants, and these can be used alone or in combination of two or more.

[0033] As the fragrance, various natural and artificial fragrances such as floral, citrus, fruity, woody, fresh note, mixed flavor, green and mint are available. Is mentioned.

[0034] The content of the disinfectant, the strength-preserving agent, the deodorant, and the fragrance as described above maintains the desired effect of each component, and from the viewpoint of obtaining safety and good economy. The ratio of the anti-viscosity fluid / viscosity agent in the total amount of the antibacterial agent and antifungal preservative is about 0.001 to about 15% by weight, more preferably about 0.003 to 8%. %. Similarly, the deodorant is preferably about 0.05 to 20% by weight, more preferably about 0.05;! To 10% by weight. Further, it is preferable that the fragrance is about 0.001 to 10% by mass, more preferably 0.0;! To 5% by mass. In addition, it is also possible to add and contain a pigment, and it can be arbitrarily set as long as it is not particularly limited, such as its blending amount and selection of color tone.

[0035] The viscosity of the body fluid leakage preventive agent of the present invention containing the above components is preferably about 6,000-50, OOOcPs, more preferably (more About 10,000 to 40, OOOcPs.

In addition, the viscosity here uses a viscometer (manufactured by Brookfield, USA, “Digital Viscometer” model: DV-1 +), spindle No. 07, rotation speed: 20 rpm, body fluid leakage prevention agent temperature: 20 Force measured at the measurement condition of ° C. It is not limited to this, and any measured value measured under similar conditions may be used.

In addition, the lower the content of the solvent (A) nooionic surfactant (E), and thus the higher the content of the superabsorbent resin powder (D), the longer the time for the bodily fluid leakage preventing agent to become jelly-like Since the liquid becomes shorter and the viscosity of the liquid increases, it is possible to adjust the liquid viscosity according to the time of jelly-form and the desired application (application site) by adjusting the amount of these ingredients S I'll do it.

[0036] The amount of the bodily fluid leakage preventing agent of the present invention injected and filled into the body cavity can be appropriately set according to the application site, and is not particularly limited. In addition, the water absorption ability of the superabsorbent resin contained in the oil jelly-like body fluid leakage prevention agent is solidified to 3,000 ml of water to form a gel and has a certain water absorption capability to prevent body fluid leakage from the body cavity. In general, 5 to 60 g force S is preferable, and 10 to 40 g is more preferable. For example, the filling amount of the bodily fluid leakage preventive agent (containing 5 to 50% by mass of the superabsorbent resin) injected into the throat from the nostril of the corpse is preferably about 8 to 40 g, more preferably about 10 to 25 g. Oil jelly-like body fluid leakage prevention If the amount of the agent to be injected is too large, the injection device becomes large, and the handling becomes difficult and the cost increases. On the other hand, if the amount to be injected is too small, it is difficult to solidify the body fluid into a gel, and there is a risk of the body fluid leaking out.

[0037] Hereinafter, specific examples of each aspect of a corpse treatment apparatus suitable for injection of the bodily fluid leakage preventing agent of the present invention will be described with reference to the accompanying drawings.

FIGS. 2 to 5 show treatment apparatuses for injecting and loading the fluid leakage preventive agent into the throat by inserting through the nostril. FIGS. 2 to 4 show the injector 10 in FIG. Represents the insertion tube 40, and the symbol X represents the body fluid leakage preventing agent of the present invention accommodated in the injector 10.

FIGS. 2 to 4 show forces indicating the injector 10. FIG. 4 shows a cross-sectional view of the state shown in FIG. 2 rotated 90 ° around the center line. As shown in FIGS. 2 to 4, the injector 10 includes a cylindrical main body 20 and a piston 30 each made of a plastic such as high-density polyethylene, polyester, and polyamide. The cylindrical main body 20 includes a cylindrical member 21 having a discharge cylinder portion 22 that functions as a discharge port portion at the tip, and a cover member 25 that is covered on the outer periphery thereof.

[0039] As is clear from FIG. 2, the cover member 25 is a cylinder having an octagonal cross section. The cover member 25 is configured so that a nurse can easily discriminate it from a general syringe in a hospital and has a distal end side. It is formed in a slightly tapered shape so that it does not easily fall off when the cylindrical member 21 is inserted. It is also possible to make it possible to clearly grasp the place of application by coloring the cover member or coloring it differently from the color of other members to make a colorful injector. As clearly shown in FIG. 4, the cover member 25 has a pair of flange portions 26 protruding outward in the radial direction for hooking a finger to the rear end portion. The distal end portion of the collar portion 26 is curved in the direction of the discharge cylinder portion 22 so that the finger can easily catch the hook. In addition, a pair of convex locking portions 23 are formed at the rear end of the cylindrical member 21, and when the collar portion 26 comes into contact with the locking portion 23, a finger is hooked on the collar portion 26 and injected. The cover member 25 is configured not to move backward from the rear end of the cylindrical member 21 when operated. Also, the protective cap 29 is removably crowned at the distal end opening of the discharge cylinder 22 after the body fluid leakage preventing agent of the present invention is filled in the injector 10. In the present embodiment, the cylindrical member 21 and the cover member 2 5 is formed as a separate body!

On the other hand, the piston 30 is slidably inserted into the cylindrical member 21 of the cylindrical main body 20 from the rear end side. The length of the piston 30 is designed to be longer than the length of the cylindrical member 21 so that the entire body fluid leakage preventing agent X in the contents can be pushed out. The piston 30 includes a piston rod 31 having a cross-shaped cross section, and a circular flange portion 32 having a diameter slightly larger than the cross-sectional dimension of the piston rod is formed at the tip of the piston 30. A gasket 34 made of synthetic resin, rubber or the like is crowned around the flange 33 formed so as to protrude from the circular flange 32. In addition, a disc-like portion 35 for touching the finger is formed at the rear end of the piston rod 31 so that the piston rod 31 can be easily pressed with the finger. When the piston 30 is inserted into the cylindrical member 21 of the cylindrical body 20 from the rear end side, the cylindrical member 21 is in a state where the gasket 34 is in contact with the inner peripheral surface of the cylindrical member 21 of the injector 10. It is configured to slide inside. Furthermore, a ring-shaped ridge 24 protruding slightly inward is formed on the inner peripheral surface in the vicinity of the rear end portion of the cylindrical member 21, and the circular flange portion of the piston rod 31 is formed on the ridge 24. The piston 30 is configured not to easily come out of the cylindrical main body 20 when it hits 32. In this embodiment, the piston rod 31 has a cross-shaped cross section, but may have a rod shape such as a circular cross section.

[0041] The insertion tube 40 is made of a flexible synthetic resin such as a polyester elastomer, a soft chlorinated resin, or a rubber that has the flexibility to crawl along the shape of the nasal cavity when inserted into the nostril. As shown in FIG. 5, the distal end portion 41 of the insertion tube 40 is formed in a substantially hemispherical shape so that the nostril can be easily inserted, and is closed, and on the side thereof, the two positions are shifted, Each has a pair of opening portions 42 in a direction perpendicular to each other, and a tapered connection portion slightly widened on the rear side for connection to the discharge tube portion 22 of the injector 10 at the rear end portion. 43. Further, at a position at a predetermined distance from the rear end of the insertion tube 40 (preferably, the front end position of the connecting portion 43), there is a stocker portion 44 having a circular cross section protruding outward in the radial direction so as to surround the outer periphery. .

[0042] The opening 42 at the tip of the insertion tube 40 can be a force S having a desired shape such as a circle or an ellipse, and the position thereof is at a distance of about 5 to 30 mm from the tip of the insertion tube. preferable. Further, the number of the opening portions 42 is four in this embodiment, but any number of! Ma In addition, the strobe portion 44 is a force that determines the length (injection position) that the opening portion 42 reaches when the insertion tube body is inserted through the nostril and into the pharynx, from the tip of the insertion tube 40 to the stubber portion 44. The length is preferably about 100 to 140 mm. The outer diameter of the insertion tube body is preferably about 3.5 to 7 mm, and the inner diameter is preferably about 2 to 5 mm.

[0043] In the above embodiment, the connecting portion 43 is formed as a body at the rear end of the insertion tube 40! However, the connecting portion 43 may be a separate body. In this case, it is preferable that the connecting portion is formed of a rigid synthetic resin. The connecting portion and the insertion tube main body are joined by an appropriate means such as an adhesive or welding. Further, the stagger portion 44 may be formed at the front end of the connection portion or may be formed at the rear end of the insertion tube. Furthermore, the insertion tube main body can be bent at a predetermined position from the distal end portion, and when inserting from the nostril to the back of the pharynx, it can be inserted smoothly without resistance. In this case, the bending position is preferably any part of a distance of about 22 to 45 mm, more preferably about 20 to 30 mm from the tip of the insertion tube body, and the bending angle is preferably 0 ° to 95 °. More preferably, it is 30 to 70 °.

[0044] When using the above corpse treatment apparatus, first, the protective cap 29 of the discharge cylinder portion 22 of the injector 10 is removed, and the discharge cylinder portion 22 is fitted into the connection portion 43 of the insertion tube 40 to insert the insertion tube 40. And connect the injector 10. Next, the insertion tube 40 is inserted from the nostril A (see FIG. 1) toward the throat B, and the insertion is stopped when the stopper portion 44 of the insertion tube 40 hits the nose tip. At this time, a lubricant may be applied to the insertion tube 40 in order to reduce the insertion resistance. Then, the piston 30 of the injector 10 is pressed, and the jelly-like body fluid leakage preventing agent X in the injector 10 is injected into the throat B through the insertion tube 40. After the body fluid leakage preventive agent X in the injector 10 is extruded and filled, the injector 10 and the insertion tube 40 are extracted from the nostril A.

In the above operation method, the insertion tube 40 is inserted into the nostril A with the injection tube 40 connected to the injector 10, but the insertion tube 40 is first inserted into the nostril A, and then the injection tube 40 is injected into the injection tube 40. 10 may be connected. In addition, the injector 10 and the insertion tube 40 may be stored in a container in a connected state, and in this case, the treatment work can be performed immediately after being taken out of the container. Alternatively, in the above-described embodiment, the injector 10 and the insertion tube 40 are separate bodies, but they may be produced integrally. Further, even if a mark is provided instead of the stopper portion 44 formed on the insertion tube 40, variations in the insertion position can be prevented to some extent. Next, a preferred embodiment of the treatment apparatus for injecting and loading the bodily fluid leakage preventing agent into the anus and / or vagina will be described with reference to FIGS.

FIGS. 6 to 8 show forces indicating the injector 10a. FIG. 8 shows a cross-sectional view of the state shown in FIG. 6 rotated 90 ° around the center line. As shown in FIGS. 6 to 8, in this embodiment as well, as in the previous embodiment, the injector 10a is a cylindrical body 20a made of a plastic such as high-density polyethylene, polyester, or polyamide. And piston 30. However, unlike the above-described embodiment, a fibrous filler (plug member) Y is housed in the injector 10a together with the gelatinous bodily fluid leakage preventing agent X. This fibrous filler Y is used in the body cavity of the anus and vagina, after the jelly-like fluid leakage preventing agent X becomes a solid gel, the muscles in each part of the body cavity relax after death and have a gap between them. Even if this occurs, it is also possible to use only the jelly-like body fluid leakage preventing agent X as a container for the purpose of reliably preventing body fluid leakage. The amount of the body fluid leakage preventing agent X (containing 5 to 50% by mass of the superabsorbent resin) contained in one device is about 1 to 10 g, more preferably about 1 to 5 g, and the length of the fibrous filler Y is It is preferable to set the diameter within a range of about 10 to 30 mm and a diameter of about 8 to 23 mm.

[0047] The cylindrical main body 20a includes a cylindrical member 21a having a discharge port portion 22a at the tip, and a cover member 25a covered on the outer periphery thereof. The discharge port portion 22a at the tip of the cylindrical member 21a is formed in a substantially hemispherical shape by a plurality of tongue pieces 28 that are curved and extended outward toward the center in the radial direction. An opening is formed from the opening at the tip and the slit between the tongue pieces. Each tongue 28 has such flexibility that it can be bent outward. When a cylindrical syringe (syringe) with a large outer diameter is inserted into the anus or vagina before it becomes rigid after death, the anal canal and vaginal opening will open widely, and it will take time to contract, so it will take time for body fluid to flow. Causes leakage. Further, the cylindrical member 21a is easier to insert and use as the outer diameter is thinner. Accordingly, it is preferable that the cylindrical member 21a has an outer diameter of about 10 to 25 mm, more preferably about 10 to 15 mm, and an inner diameter of about 8 to 23 mm.

As apparent from FIG. 6, the cover member 25a is a cylinder having an octagonal cross section, and is configured so that a nurse can easily distinguish it from a general syringe in a hospital. It should be noted that the cover member is colored, or the color is different from the color of other members. By doing so, it is possible to clearly grasp the application place. As clearly shown in FIG. 8, the rear end portion of the cylindrical member 21a is provided with a pair of flange portions 26 protruding outward in the radial direction for hooking a finger, while the cover member 25a has a cap-shaped sting collar portion 27 that expands rearward at the tip. It is preferable to set the tip force of the cylindrical member 21a to the stopper portion 27 within a range of about 15 to 50 mm. The height of the stopper portion 27 from the outer peripheral surface of the cylindrical member 21a is easily It is preferable to set it within the range of about 5 to 30 mm so that it stops at the vaginal opening. It should be noted that the stopper portion 27 does not necessarily need to be inserted into the anus or vagina for a predetermined length into the anus or vagina, as in this embodiment. As long as it is a member or mark that can be secured, it may be a disk or a mark that can be easily visually confirmed. Further, the distal end portion of the collar portion 26 is curved in the direction of the discharge port portion 22a, so that the finger can easily catch the hooking force. The height of the collar portion 26 from the outer peripheral surface of the cylindrical member 21a is preferably about 5 to 18 mm, and the degree of curvature of the tip portion is preferably set in the range of 0 to 50 °. When such a cover member is used, the above-described collar portion and the strobe portion may be provided at a predetermined position of the cover member. Preferably, however, as in the present embodiment, the strobe portion is the tip of the cover member or the cover member. When the cover member has the same length as that of the cylindrical member, it is desirable to provide the substantially intermediate portion and the flange portion at the rear end portion of the cylindrical member.

[0049] Furthermore, a rear end of the cylindrical member 21a is formed with a pair of convex locking portions 23a that are continuous with the pair of flanges 26 and project laterally. The cover member 25a is configured not to move backward from the rear end of the cylindrical member 21a when the finger 26 is hooked with the finger on the hook part 26 and the injection operation is performed by contacting the locking part 23a and the hook part 26. ing. Further, the protective cap 29a is removably crowned at the tip of the cylindrical member 21a after the injector 10 is filled with the bodily fluid leakage preventing agent of the present invention. Also in the present embodiment, the cylindrical member 21a and the cover member 25a may be integrally formed with a force formed separately.

[0050] On the other hand, the structure of the piston 30 is the same as that of the above-described embodiment, and is slidably inserted into the cylindrical member 21a of the cylindrical main body 20a from the rear end side. The length of the piston 30 is a cylindrical member so that the body fluid leakage preventive agent X and the fibrous filler Y can be pushed out. Designed to be longer than 21 a. The piston 30 includes a piston rod 31 having a cross-shaped cross section, and a circular flange portion 32 having a diameter slightly larger than the cross-sectional dimension of the piston rod is formed at a tip portion thereof. A gasket 34 made of synthetic resin, rubber, or the like is crowned around the flange 33 formed so as to protrude from the circular flange 32. In addition, a disc-like portion 35 to which the finger is applied is formed at the rear end of the piston rod 31 so that the piston rod 31 can be easily pressed with the finger.

[0051] When the piston 30 is inserted into the cylindrical member 21a of the cylindrical body 20 from the rear end side, the gasket 34 is in a state where the gasket 34 is in contact with the inner peripheral surface of the cylindrical member 21a of the injector 10. It is configured to slide in the member 21a. Furthermore, a ring-shaped ridge 24 that protrudes slightly inward is formed on the inner peripheral surface in the vicinity of the rear end of the cylindrical member 21a, and the circular flange portion of the piston rod 31 is formed on the ridge 24. The piston 30 is configured so that it does not easily come out of the cylindrical body 20 by hitting 32. In this embodiment as well, the piston opening 31 may be in the form of a rod having a cross-sectional shape with a circular cross section.

[0052] When using the treatment device for injecting and filling the body fluid leakage preventing agent X and the fibrous filler Y into the anus and / or vagina, first, a protective cap for the discharge port 22a of the injector 10a is used. Without removing 29a, insert it into the anus or vagina as it is, and stop the insertion when the stopper part 27 hits the outside of the anus or vagina. At this time, in order to reduce insertion resistance, a lubricant may be applied to the protective cap 29a. Then, the piston 30 of the injector 10a is pressed, and the jelly-like body fluid leakage preventing agent X and the fibrous filler Y in the injector 10a are injected together with the protective cap 29a. At that time, the superabsorbent resin powder in the bodily fluid leakage preventive agent X that has absorbed the bodily fluid and filth liquid expands, and part of it penetrates into the fibrous filler Y and becomes a solid gel. Therefore, it is possible to effectively prevent leakage of body fluids and filth. Thereafter, the injector 10a is removed from the anus and vagina.

[0053] The fibrous filler Y is a non-woven fabric of superabsorbent resin fibers, compressed pulp paper, cotton, cotton and superabsorbent resin fiber blends, molded articles of superabsorbent resin fibers, synthetic fiber nonwoven fabrics, Runseal (registered trademark) F or ranseal (registered trademark) manufactured by Toyobo Co., Ltd., which is composed of an inner layer of water-swellable fibers such as acrylic fibers and an outer layer made of a water-absorbing resin. K molded into a cylindrical shape, or pulp compression molded into a cylindrical shape It's preferable to use a bowl (eg tampons for women).

[0054] A treatment device for injecting and loading a body fluid leakage preventing agent into the throat and inserting it through the nostril as described above, and a treatment device for injecting and loading the body fluid leakage preventing agent into the anus and / or vagina The body treatment device unit is housed in a single container together with a fiber sealing material for preventing leakage of body fluid from the ear and / or nostril, or a fiber sealing material for loading in the mouth. As a result, it is convenient to carry and the body can be treated quickly.

[0055] The fiber sealing material for preventing leakage of body fluids from the ear canal and nostril is made of cotton, superabsorbent resin fiber, blend of cotton and superabsorbent resin fiber, and non-woven fabric, spherical, columnar, cubic What was shape | molded into desired shapes, such as, can be used suitably. It is preferable to have two sealing materials for earplugs and two for nasal plugs.

In addition, the fiber sealing material for loading in the mouth is intended to prevent leakage of bodily fluids and form the bulge of the heel in a direction closer to the natural bulge, as described above. Cotton, cotton and superabsorbent resin fiber blend, cloth or non-woven fabric such as superabsorbent resin fiber, or non-woven fabric of cotton and superabsorbent resin fiber, or these single component members in any layer structure A sealing material composed of members laminated in a sand switch shape can be suitably used.

As described above, each aspect of the corpse treatment apparatus suitable for injecting the bodily fluid leakage preventing agent of the present invention has been described with reference to the accompanying drawings. However, the oil jelly-like bodily fluid leakage preventing agent of the present invention is conventionally known. It can be injected and loaded into the body cavity such as the mouth, nose, ears, anus, and vagina of a woman and sealed with a liquid, and is not limited to the above-mentioned embodiments! Needless to say,

Example

[0057] In the following, the power of the examples and test examples in which the effects of the bodily fluid leakage preventing agent of the present invention have been specifically confirmed are shown, and it is needless to say that the present invention is not limited to the following examples.

[0058] Examples;! To 5 and Comparative Example 1

With the formulation and blending ratio shown in Table 1, superabsorbent with stirring into a viscous solution in which a dispersion stabilizer, thickener and other additives are dissolved in an ether solvent (Sunfine DM-200). Gradually add a specified amount of resin powder to uniformly disperse highly water-absorbent resin powder. A Lee-like body fluid leakage preventing agent was prepared (Examples;! To 5). For comparison, a highly water-absorbent resin powder is uniformly dispersed in a solution obtained by dissolving an acrylic acid polymer (alkali salt of carboxybule polymer) as a gelling agent in ethylene glycol, which is an alcohol solvent. A body fluid leakage preventing agent was prepared (Comparative Example 1).

The water absorption rates of the body fluid leakage preventing agents thus prepared were compared by the following test methods.

[0059] Test Example 1 (Water absorption rate test of test sample)

Test method:

Sample lg was weighed into a 100 ml beaker, then 8 Oml of ion exchange water (20 ° C) was gently injected, and the time until all of the ion exchange water became jelly was measured.

Yes

The test results are also shown in Table 1.

[0060] [Table 1]

Test sample No. Example No.

Comparative example (% by mass) 1 2 3 4 5 1 Sunfine DM-200 * ¹ 70 60 60 69 59 ― Ethylene glycol ― ― ― ― ― 79.4 Carboxyvinyl polymer

*-----0.2 Triethanolamine-----0.4 Treatment

PEG-200 * ³ ― 10 ― ― ― ―

Sannonic SS- 120 * ⁴ ― ― 10 ― 10 ― Super absorbent polymer powder ⁴⁵ 25 25 25 25 25 20 Thermoplastic nonionic type

5 5 5 5 5 ― Water-absorbent resin * ⁶

Ethyl cellulose "― ― ― 1 1 ― (49%> ethoxy group)

Total 100 100 100 100 100 100

Result

Time in seconds. 65 58 97 74 118 510 fruit

(Average of 3 times)

* ¹ Sunfine DM-200: manufactured by Sanyo Chemical Industries

Polyoxyethylene dimethyl ether

* ² Power Lupoxyvinyl Polymer: Product Name Γ Hibis Koichi j Wako Pure Chemical Industries, Ltd. * ³ PEG—200: Polyethylene glycol with an average molecular weight of about 200

Preparation

"Sannonic SS-120: Nonionic surfactant manufactured by Sanyo Chemical Industries, Ltd.

Polyoxyethylene alkyl ether

* ⁵ Superabsorbent powder: Brand name “AKK Keep J Sumitomo Seika Co., Ltd.

* ⁶ Thermoplastic nonionic water-absorbing resin: Trade name: Γ-Acco Co., Ltd. J Sumitomo Seika Co., Ltd. * ⁷ Ethylcellulose (approx. 49 «½ ethoxy group): Wako Pure Chemical Industries, Ltd. Reagent As apparent from the results shown in Table 1 above In addition, in the case of Comparative Example 1 using an alcohol base, it takes a long time to prepare the bodily fluid leakage preventing agent, which indicates that workability is poor. On the other hand, in Examples:! To 5 of the present invention, even when the amount of the superabsorbent resin powder added is increased, the dispersion stability when left for a long time is excellent, and compared with Comparative Example 1. Although the amount of the superabsorbent resin powder added was slightly increased, the time required to make the entire ion-exchanged water jelly-like could be greatly reduced. From this, it can be seen that the bodily fluid leakage preventing agent of the present invention is optimal as a bodily fluid leakage preventing agent that quickly solidifies into a solid jelly having no fluidity to prevent bodily fluid leakage. [0062] Since polyoxyethylene dimethyl ether (Sunfine DM-200) used in each of the above examples is a smooth liquid with low viscosity, it is easily mixed with water, and the highly water-absorbent resin powder absorbs water. It seems to make it easier. However, since the solvent tends to come out first when injected with an injector and it tends to be difficult to inject, the PEG-200, Sannonic as in Examples 2 and 3 to make the composition viscous. It is preferable to add SS-120 or add a thickener such as ethyl ether as in Examples 4 and 5.

Sannonic SS-120 (polyoxyethylene alkyl ether) dissolves ethylcellulose (about 49% ethoxy group) and thickens. Ethylcellulose dissolves in nonpolar solvents and becomes difficult to dissolve in polar solvents as the degree of substitution of ethoxy groups increases. Usually, those in which 43 to 50% of ethoxy groups are substituted are soluble in nonpolar solvents. As in Example 4 above, when 1% of ethyl cellulose is added, the water absorption rate is fast, the stability is good, and an ideal oil jelly-like body fluid leakage preventing agent that does not separate even if left for a long time is prepared. it can. However, when a large amount of ethyl cellulose is added, the water absorption rate tends to deteriorate. Therefore, in the case of the formulation as in the above Examples, the addition amount of ethyl cellulose is preferably 0.2 to 5%. In particular, 0.5 to 1.5% is desirable. In the case of a thickened solution obtained by dissolving ethyl cellulose in Sannonic SS-120, it is difficult to separate and form a jelly when a polar solvent is added. It is preferable to avoid the addition. In addition, when Nouon surfactant is added to a solution obtained by dissolving ethyl cellulose in Sannonic SS-120 and increasing the viscosity as in Example 5, the water absorption speed is slightly reduced S, and the jelly-like material slips. Better, injection into the body cavity 'smooth filling.

[0063] Examples 6-; 10

An oil jelly-like body fluid leakage preventing agent in which the superabsorbent resin powder was uniformly dispersed was prepared with the formulation and blending ratio shown in Table 2.

The water absorption rate of the body fluid leakage preventing agent thus prepared was tested in the same manner as in Test Example 1. The test results are also shown in Table 2.

[0064] [Table 2] Test sample No. Example No.

(Mass%) 6 7 8 9 10 Sunfine DM-200 * ¹ 69.8 68.8 67.8 57.8 58.8

PEG-200 * ² ― ― ― 10 ― Sannonic SS- 120 * ³ ― ― ― ― 10

萬 Water-absorbent resin powder * ⁴ 25 25 25 25 25 Thermoplastic nonionic type

5 6 7 7 6 Water-absorbing resin ' ⁵

Viscosta 50K * ⁶ 0.2 0.2 0.2 0.2 0.2 Total 100 100 100 100 100 Time to jelly

? fa

Between (seconds). 42 56 65 86 118 fruit

(Average of 3 times)

"Sunfine DM-200: made by Sanyo Chemical Industries

Polyoxyethylene dimethyl ether

* ² PEG-200: Polyethylene glycol with an average molecular weight of about 200

* ³ Sannonic SS-120: Nonionic surfactant manufactured by Sanyo Chemical Industries, Ltd. Consideration Polyoxyethylene alkyl ether

"High water-absorbing resin powder: Trade name: Γ-keep" manufactured by Sumitomo Chemical Co., Ltd.

* ⁵ Thermoplastic nonionic water-absorbing resin: Product name ΓArk ヮ Coke J Sumitomo Seika Co., Ltd. * ⁶ Viscostar 50K: Mitsui Chemicals Polyurethane Inc. thickener (urethane resin) In Examples 6 to 10 above, thickener The added Viscostar 50K (powder) dissolves in an ether solvent (Sunfine DM-200) and thickens to become a viscous liquid. Viscostar 50K (powder) also dissolves easily in water and becomes a viscous liquid. Therefore, Viscostar 50K (powder) is a very good raw material as a thickener for ether solvents. However, when added in a large amount to the formulation of oil jelly, it tends to be in an agglomerated state and is difficult to inject with a syringe. In the case of the formulation as in the above example, Viscostar 50K (powder) The addition amount of 0.;! ~ 6% is preferred, especially 0.;! ~ 2% is desirable. Further, when the amount of the heat-plastic nonionic water-absorbing resin is increased as in Examples 8 and 9, the viscosity of the oil jelly-like material is improved and the filling property into the injector is improved. However, if a large amount of thermoplastic noun type water-absorbing resin is added, the viscosity of the oil jelly increases, and the water absorption rate tends to deteriorate little by little. Therefore, it is not preferable to add a large amount. In addition, as in Example 9, when a small amount of PEG-200 is added, the oil jelly-like product becomes soft and soft, and the filling is smooth. It becomes. However, since the water absorption rate tends to deteriorate because it becomes a viscous liquid, it is preferable to add a large amount. Similarly, as in Example 10, when a nonionic surfactant (Sannonic SS-120) is added, the water absorption rate tends to deteriorate, so it is not preferable to add a large amount.

[0066] Examples 11-; 17

An oil jelly-like body fluid leakage preventing agent in which the superabsorbent resin powder was uniformly dispersed was prepared with the formulation and blending ratio shown in Table 3. The obtained oil jelly-like body fluid leakage preventing agent was excellent in water absorption rate.

[0067] [Table 3]

[0068] Examples 18-22

In a beaker, add a certain amount of ether-based melt lj (Sunfine DM-200) and PEG-200. Add a certain amount of each of the dispersion stabilizers shown in Table 4 below while stirring and dissolve them by heating (select any temperature depending on the dispersion stabilizer), and then add a thickener (viscostar). 50K) was added and dissolved to obtain a viscous solution. Into this, a specified amount of the superabsorbent resin powder was gradually added, and the mixture was returned to room temperature with stirring to prepare an oil repellent body fluid leakage preventing agent in which the superabsorbent resin powder was uniformly dispersed.

The water absorption rate of the body fluid leakage preventing agent thus prepared was tested in the same manner as in Test Example 1. The test results are also shown in Table 4.

[Table 4] Sample No. Example No.

(Mass%) 9 20 21 22 Sunfine DM—200 67.8 57,8 64.5 54.5 58.6

PEG— 200 10.0 10.0 15.0 水性 Water absorbent resin powder * ^; 25.0 25.0 25.0 25.0 25.0 Thermoplastic nonionic water absorbent resin

'• 0

Fat * ⁴

Acrylic acid polymer carboxy

0.4 Vinyl polymer * ⁵

Lipophilic smectite * 10.0 10.0 Piscostar 50K * 0.2 0.2 0.5 0.5 2.0 Time to jelly (seconds)

62 88 100 132 86 + 3 average values>

* ¹ Sun Fine DM-200: Sanyo Chemical Industries, Ltd.

Polyoxyethylene dimethyl ether

* ² PEG-200: Polyethylene glycol with an average molecular weight of about 200

"High water-absorbent resin powder: manufactured by Sumitomo Gakka Co., Ltd.

' ⁴ Thermoplastic nonionic water-absorbing resin: manufactured by Sumitomo Seika Co., Ltd.

* ⁵ Carboxyvinyl polymer of acrylic acid polymer: Wako Pure Chemical Industries,

Product name “Hibisu Koichi j

* ⁶ Lipophilic smectite: Co-op Chemical Co., Ltd., trade name “Lucentite J”

* ⁷ Piscostar 50K: Mitsui Chemicals Polyurethane Co., Ltd. glazed adhesive (urethane resin) Test Example 2 (Exothermic temperature measurement test of test materials)

Test method:

10 g of each raw material shown in Table 5 was weighed into a 30 ml beaker, and the exothermic temperature of the mixed solution when 8 g of water was injected was measured under the following conditions. Measuring instrument: DATA COLLECTOR temperature sensor for liquid manufactured by Anritsu Keiki Co., Ltd. Room temperature when measuring: 22.3. C.

The test results are also shown in Table 5.

[Table 5]

[0072] As shown in Table 5 above, in the case of liquid PEG200, heat was generated immediately when mixed with water, it quickly became soluble in water, and the temperature level could be maintained for a certain period of time. On the other hand, in the case of alcoholic solvents such as anhydrous glycerin, ethylene glycol, and ethyl alcohol, a slight heat generation after mixing with water, the temperature level is quite low and the temperature level cannot be maintained. In view of this, liquid PEG200 is suitable for increasing the liquid absorption speed of the highly water-absorbent resin.

Industrial applicability

[0073] The bodily fluid leakage preventive agent of the present invention absorbs bodily fluids quickly when it comes into contact with bodily fluids in the body cavity by injecting into body cavities such as the mouth, nose, ears, anus, and female vagina with an infusion device 'Because it swells and hardens, it can be used advantageously to prevent fluid leakage from the body.

Claims

The scope of the claims

[1] At least one solvent (A) selected from the group consisting of hydrophilic ethers and esters, a polyalkylene oxide-based thermoplastic nonionic water-absorbing resin, a carboxybule polymer that is a polymer of acrylic acid, At least one dispersion stabilizer (B) selected from the group consisting of a polymer of acrylic acid, a carboxybule polymer / alkali neutralizer, a lipophilic smectite, a synthetic hectorite, a natural hectorite, and a bentonite. Alternatively, a body fluid leakage preventive agent characterized by that the superabsorbent resin powder (D) is dispersed in a viscous liquid base containing the thickener (C).

[2] The body fluid leakage preventing agent according to claim 1, wherein the solvent (A) is at least one selected from the group consisting of polyoxyethylene dimethyl ether and polyoxyethylene fatty acid diester.

[3] The body fluid leakage preventing agent according to claim 1 or 2, wherein the dispersion stabilizer (B) is a polyalkylene oxide-based thermoplastic nonionic water-absorbing resin.

[4] The thickener (C) force is at least one selected from the group consisting of urethane resin, polybutyl ether, ethyl cellulose and polyethylene oxide. The body fluid leakage preventing agent according to claim 1.

[5] It further contains at least one selected from the group consisting of a liquid noionic surfactant (E) that generates heat when mixed with water and a water-soluble alcoholic organic solvent (F). The bodily fluid leakage preventive agent according to any one of claims 1 to 4.