WO2008001360A3 - Compositions and methods for treating and preventing gastro esophageal reflux disease - Google Patents
Compositions and methods for treating and preventing gastro esophageal reflux disease Download PDFInfo
- Publication number
- WO2008001360A3 WO2008001360A3 PCT/IL2007/000773 IL2007000773W WO2008001360A3 WO 2008001360 A3 WO2008001360 A3 WO 2008001360A3 IL 2007000773 W IL2007000773 W IL 2007000773W WO 2008001360 A3 WO2008001360 A3 WO 2008001360A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- gerd
- compositions
- treating
- reflux disease
- esophageal reflux
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Botany (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to methods and compositions effective in treating, preventing, reducing the severity of, or relieving the symptoms of, Gastro Esophageal Reflux Disease (GERD). The compositions comprise, as an active ingredient, an extract from the plant genus Conyza Less, preferably from the species Conyza bonariensis (L) Cronq. The composition comprises only natural ingredients and has been demonstrated to be safe for use, while still providing a beneficial therapeutic effect. The composition can also be administered in combination with traditional anti-GERD medicines, either over-the-counter or prescription medicines such as antacids, H2-receptor agonists, proton pump inhibitors, promotility agents and Sucralfate. The compositions are particularly effective in treating and preventing GERD, the symptoms or GERD and conditions associated with GERD, including heartburn, regurgitation, esophagitis, Non-Erosive Esophageal Reflux Disease (NERD), Barrett's Esophagus, and any combination thereof.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07766804A EP2043669A4 (en) | 2006-06-28 | 2007-06-26 | Compositions and methods for treating and preventing gastro esophageal reflux disease |
CA002656220A CA2656220A1 (en) | 2006-06-28 | 2007-06-26 | Compositions and methods for treating and preventing gastro esophageal reflux disease |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL176608A IL176608A0 (en) | 2006-06-28 | 2006-06-28 | Compositions and methods for treating and preventing gastro esophageal reflux disease |
IL176608 | 2006-06-28 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2008001360A2 WO2008001360A2 (en) | 2008-01-03 |
WO2008001360A3 true WO2008001360A3 (en) | 2009-04-30 |
Family
ID=38846091
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IL2007/000773 WO2008001360A2 (en) | 2006-06-28 | 2007-06-26 | Compositions and methods for treating and preventing gastro esophageal reflux disease |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP2043669A4 (en) |
CA (1) | CA2656220A1 (en) |
IL (1) | IL176608A0 (en) |
WO (1) | WO2008001360A2 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108578654A (en) * | 2018-05-22 | 2018-09-28 | 中国中医科学院西苑医院 | A kind of Chinese medicine composition and preparation method thereof for treating Non-erosive reflux disease |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT201700090582A1 (en) * | 2017-08-04 | 2019-02-04 | Neilos S R L | Composition for use in the prevention and / or treatment of gastric or gastroesophageal disorders. |
CN110353271B (en) * | 2019-06-13 | 2022-07-22 | 陕西科技大学 | Special medical food thickening component for inhibiting esophagus reflux and preparation method thereof |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101032333A (en) * | 2007-04-11 | 2007-09-12 | 朱西杰 | Herbal meal of gastrointestinal sustained release particle for protecting gastrointestinal mucosa |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1340356A (en) * | 2000-08-28 | 2002-03-20 | 黄兴 | Chinese medicine for treating enterogastric disease |
FR2843125B1 (en) * | 2002-08-02 | 2012-11-16 | Coletica | ACTIVE PRINCIPLES STIMULATING HUMAN BETA-DEFENSIVE TYPE 2 AND / OR TYPE 3, AND COSMETIC OR PHARMACEUTICAL COMPOSITIONS COMPRISING SUCH ACTIVE INGREDIENTS |
-
2006
- 2006-06-28 IL IL176608A patent/IL176608A0/en unknown
-
2007
- 2007-06-26 WO PCT/IL2007/000773 patent/WO2008001360A2/en active Application Filing
- 2007-06-26 EP EP07766804A patent/EP2043669A4/en not_active Withdrawn
- 2007-06-26 CA CA002656220A patent/CA2656220A1/en not_active Abandoned
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101032333A (en) * | 2007-04-11 | 2007-09-12 | 朱西杰 | Herbal meal of gastrointestinal sustained release particle for protecting gastrointestinal mucosa |
Non-Patent Citations (2)
Title |
---|
KONG, L. D. ET AL.: "Glycosides and Xanthine Oxidase Inhibitors from Conyza bonariensis", vol. 58, no. 4, October 2001 (2001-10-01), pages 645 - 651, XP004306136 * |
SOUZA, M.C. ET AL.: "Evaluation of Anti-Inflammatory Activity of Essential Oils from two Asteraceae Species.", PHARMAZIE., vol. 58, no. 8, August 2003 (2003-08-01), pages 582 - 586, XP001537158 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108578654A (en) * | 2018-05-22 | 2018-09-28 | 中国中医科学院西苑医院 | A kind of Chinese medicine composition and preparation method thereof for treating Non-erosive reflux disease |
CN108578654B (en) * | 2018-05-22 | 2021-11-12 | 中国中医科学院西苑医院 | Traditional Chinese medicine composition for treating non-erosive reflux disease and preparation method thereof |
Also Published As
Publication number | Publication date |
---|---|
WO2008001360A2 (en) | 2008-01-03 |
EP2043669A4 (en) | 2011-06-22 |
CA2656220A1 (en) | 2008-01-03 |
EP2043669A2 (en) | 2009-04-08 |
IL176608A0 (en) | 2006-10-31 |
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