WO2007149361A3 - Modèles poisson zèbre pour l'analyse de la fonction cardiaque - Google Patents
Modèles poisson zèbre pour l'analyse de la fonction cardiaque Download PDFInfo
- Publication number
- WO2007149361A3 WO2007149361A3 PCT/US2007/014144 US2007014144W WO2007149361A3 WO 2007149361 A3 WO2007149361 A3 WO 2007149361A3 US 2007014144 W US2007014144 W US 2007014144W WO 2007149361 A3 WO2007149361 A3 WO 2007149361A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- analysis
- methods
- heart function
- systems
- zebrafish
- Prior art date
Links
- 241000252212 Danio rerio Species 0.000 title abstract 2
- 230000004217 heart function Effects 0.000 title 1
- 206010003119 arrhythmia Diseases 0.000 abstract 2
- 230000006793 arrhythmia Effects 0.000 abstract 2
- 230000002763 arrhythmic effect Effects 0.000 abstract 1
- 230000000747 cardiac effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
- A61K49/0045—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent agent being a peptide or protein used for imaging or diagnosis in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
- A61K49/0045—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent agent being a peptide or protein used for imaging or diagnosis in vivo
- A61K49/0047—Green fluorescent protein [GFP]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43595—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from coelenteratae, e.g. medusae
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/40—Fish
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/035—Animal model for multifactorial diseases
- A01K2267/0375—Animal model for cardiovascular diseases
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/0393—Animal model comprising a reporter system for screening tests
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Epidemiology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Environmental Sciences (AREA)
- Public Health (AREA)
- General Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Toxicology (AREA)
- Plant Pathology (AREA)
- Biodiversity & Conservation Biology (AREA)
- Microbiology (AREA)
- Animal Husbandry (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
L'invention porte sur des procédés et des systèmes de détection de l'arythmie chez le poisson zèbre, ainsi que des procédés et des systèmes pour classer un tracé de rythme cardiaque parmi les arythmies. L'invention concerne également des procédés et des systèmes d'identification d'agents provoquant des arythmies, et des procédés d'identification d'agents modulant la contractilité cardiaque.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US81446406P | 2006-06-16 | 2006-06-16 | |
US60/814,464 | 2006-06-16 | ||
US83651506P | 2006-08-09 | 2006-08-09 | |
US60/836,515 | 2006-08-09 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2007149361A2 WO2007149361A2 (fr) | 2007-12-27 |
WO2007149361A3 true WO2007149361A3 (fr) | 2008-05-02 |
Family
ID=38834031
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2007/014144 WO2007149361A2 (fr) | 2006-06-16 | 2007-06-18 | Modèles poisson zèbre pour l'analyse de la fonction cardiaque |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2007149361A2 (fr) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2013329415A1 (en) * | 2012-10-08 | 2015-04-23 | University of Virginia Patent Foundation, d/b/a University of Virginia Licensing & Ventures Group | Miniaturized multiwell plate reader for phenotypic screening |
CN115250971B (zh) * | 2022-07-13 | 2023-07-14 | 山东省科学院生物研究所 | 一种斑马鱼心肌缺氧模型的建立方法及应用 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040133114A1 (en) * | 2002-11-20 | 2004-07-08 | Macrae Calum A. | Zebrafish Assay |
US20040143865A1 (en) * | 2002-12-06 | 2004-07-22 | Rubinstein Amy L. | Transgenic zebrafish models for angiogenesis |
-
2007
- 2007-06-18 WO PCT/US2007/014144 patent/WO2007149361A2/fr active Application Filing
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040133114A1 (en) * | 2002-11-20 | 2004-07-08 | Macrae Calum A. | Zebrafish Assay |
US20040143865A1 (en) * | 2002-12-06 | 2004-07-22 | Rubinstein Amy L. | Transgenic zebrafish models for angiogenesis |
Also Published As
Publication number | Publication date |
---|---|
WO2007149361A2 (fr) | 2007-12-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2006010150A3 (fr) | Gènes domestiques et méthodes d'identification desdits gènes | |
USD653517S1 (en) | Tool bit | |
WO2007076439A3 (fr) | Procede et combinaisons de marqueurs permettant de depister une predisposition au cancer du poumon | |
GB0806007D0 (en) | Real time target topography during laser processing | |
AP2238A (en) | Gravity gradiometer. | |
GB2414072B (en) | Classification method for sedimentary rocks | |
IL183501A0 (en) | Lung cancer prognostics | |
EP1806003A4 (fr) | Etiquettes meres | |
DE602006006759D1 (de) | Vorrichtung zum Nachweis von Reaktionen | |
GB2434829B (en) | Hidden deck fastener system | |
DE602006002359D1 (de) | Vorrichtung zur Unterscheidung von Münzwerten | |
EP1865835A4 (fr) | Systeme et procedes de declenchement de signaux cardiaques | |
WO2006122046A3 (fr) | Therapies pour maladies vasculaires | |
WO2006002225A8 (fr) | Systeme de classification a amelioration automatique | |
EP1960942A4 (fr) | Procedes et systemes de detection d'objets dissimules | |
EP1891563A4 (fr) | Systeme d'analyse distribue | |
WO2007149361A3 (fr) | Modèles poisson zèbre pour l'analyse de la fonction cardiaque | |
USD709621S1 (en) | Data door for an analysis system | |
WO2007079141A3 (fr) | Procede d'identification de composes utiles pour le traitement de maladies degeneratives neuronales | |
GB0505462D0 (en) | Improved sprinkler test system | |
DE602006014659D1 (de) | Verfahren zur identifizierung von purkinje-zellen unter verwendung des corl2-gens als ziel | |
WO2008021015A3 (fr) | Procédés de fabrication d'esters de camptothécines | |
GB0501076D0 (en) | Dawn simulator | |
WO2005072241A3 (fr) | Inhibition de la fonction de bright permettant de traiter une production excessive d'immunoglobulines | |
USD691283S1 (en) | Enclosure for diagnostic analyzer |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
121 | Ep: the epo has been informed by wipo that ep was designated in this application |
Ref document number: 07796193 Country of ref document: EP Kind code of ref document: A2 |
|
NENP | Non-entry into the national phase |
Ref country code: DE |
|
NENP | Non-entry into the national phase |
Ref country code: RU |
|
122 | Ep: pct application non-entry in european phase |
Ref document number: 07796193 Country of ref document: EP Kind code of ref document: A2 |