WO2007143745A3 - Substituted phenyl acetic acids as dp-2 antagonists - Google Patents

Substituted phenyl acetic acids as dp-2 antagonists Download PDF

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Publication number
WO2007143745A3
WO2007143745A3 PCT/US2007/070803 US2007070803W WO2007143745A3 WO 2007143745 A3 WO2007143745 A3 WO 2007143745A3 US 2007070803 W US2007070803 W US 2007070803W WO 2007143745 A3 WO2007143745 A3 WO 2007143745A3
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WIPO (PCT)
Prior art keywords
substituted phenyl
phenyl acetic
antagonists
acetic acids
methods
Prior art date
Application number
PCT/US2007/070803
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French (fr)
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WO2007143745A2 (en
Inventor
Thomas Dudler
Francine Farouz
Kerry Fowler
Nataly Hawthorn
Danwen Huang
Angela Judkins
Musong Kim
Joshua Odingo
Amy Oliver
Mark Reed
Fuqiang Ruan
Eugene Thorsett
Original Assignee
Icos Corp
Thomas Dudler
Francine Farouz
Kerry Fowler
Nataly Hawthorn
Danwen Huang
Angela Judkins
Musong Kim
Joshua Odingo
Amy Oliver
Mark Reed
Fuqiang Ruan
Eugene Thorsett
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Publication date
Application filed by Icos Corp, Thomas Dudler, Francine Farouz, Kerry Fowler, Nataly Hawthorn, Danwen Huang, Angela Judkins, Musong Kim, Joshua Odingo, Amy Oliver, Mark Reed, Fuqiang Ruan, Eugene Thorsett filed Critical Icos Corp
Priority to EA200802415A priority Critical patent/EA200802415A1/en
Priority to MX2008015696A priority patent/MX2008015696A/en
Priority to BRPI0712301-9A priority patent/BRPI0712301A2/en
Priority to AU2007256597A priority patent/AU2007256597A1/en
Priority to EP07812086A priority patent/EP2044044A2/en
Priority to CA002654784A priority patent/CA2654784A1/en
Priority to JP2009514556A priority patent/JP2009539880A/en
Publication of WO2007143745A2 publication Critical patent/WO2007143745A2/en
Publication of WO2007143745A3 publication Critical patent/WO2007143745A3/en
Priority to NO20090138A priority patent/NO20090138L/en

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Abstract

Substituted phenyl acetic acid compounds of formula (I), pharmaceutical compositions, methods for their preparation and methods are provided that are useful in the treatment and prevention of disorders or conditions responsive to DP 2 receptor modulation, in particular, inflammatory and immune related disorders and conditions, such as asthma, allergic rhinitis and atopic dermatitis.
PCT/US2007/070803 2006-06-09 2007-06-08 Substituted phenyl acetic acids as dp-2 antagonists WO2007143745A2 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
EA200802415A EA200802415A1 (en) 2006-06-09 2007-06-08 REPLACED PHENYLACETIC ACIDS AS A DP-2-ANTAGONIST
MX2008015696A MX2008015696A (en) 2006-06-09 2007-06-08 Substituted phenyl acetic acids as dp-2 antagonists.
BRPI0712301-9A BRPI0712301A2 (en) 2006-06-09 2007-06-08 compound, pharmaceutical composition, method of antagonizing a dp-2 receptor, and use of a compound
AU2007256597A AU2007256597A1 (en) 2006-06-09 2007-06-08 Substituted phenyl acetic acids as DP-2 antagonists
EP07812086A EP2044044A2 (en) 2006-06-09 2007-06-08 Substituted phenyl acetic acids as dp-2 antagonists
CA002654784A CA2654784A1 (en) 2006-06-09 2007-06-08 Substituted phenylacetic acids as dp-2 antagonists
JP2009514556A JP2009539880A (en) 2006-06-09 2007-06-08 Substituted phenylacetic acid as a DP-2 antagonist
NO20090138A NO20090138L (en) 2006-06-09 2009-01-09 Substituted phenyl acetic acids as DP-2 antagonists

Applications Claiming Priority (2)

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US81239806P 2006-06-09 2006-06-09
US60/812,398 2006-06-09

Publications (2)

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WO2007143745A2 WO2007143745A2 (en) 2007-12-13
WO2007143745A3 true WO2007143745A3 (en) 2008-04-17

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JP (1) JP2009539880A (en)
CN (1) CN101490024A (en)
AU (1) AU2007256597A1 (en)
BR (1) BRPI0712301A2 (en)
CA (1) CA2654784A1 (en)
EA (1) EA200802415A1 (en)
MX (1) MX2008015696A (en)
NO (1) NO20090138L (en)
WO (1) WO2007143745A2 (en)

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BRPI0818773A2 (en) * 2007-10-19 2015-04-14 Janssen Pharmaceutica Nv CARBON-CONNECTED RANGE-SECRETASE MODULATORS
EA018862B1 (en) * 2007-10-19 2013-11-29 Янссен Фармацевтика, Н.В. MODULATORS OF γ-SECRETASE
CN103096893B (en) 2010-06-04 2016-05-04 阿尔巴尼分子研究公司 Glycine transporter-1 inhibitor, Its Preparation Method And Use
JP5800898B2 (en) 2010-07-05 2015-10-28 アクテリオン ファーマシューティカルズ リミテッドＡｃｔｅｌｉｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｌｔｄ 1-Phenyl-substituted heterocyclyl derivatives and their use as prostaglandin D2 receptor modulators
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CN112300120B (en) * 2019-07-31 2023-04-14 北京四环制药有限公司 Compound for preparing balsalavir or derivatives thereof, preparation method and application thereof
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EA200802415A1 (en) 2009-06-30
CN101490024A (en) 2009-07-22
BRPI0712301A2 (en) 2012-01-17
WO2007143745A2 (en) 2007-12-13
NO20090138L (en) 2009-03-05
MX2008015696A (en) 2009-02-10
JP2009539880A (en) 2009-11-19
EP2044044A2 (en) 2009-04-08
AU2007256597A1 (en) 2007-12-13

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