WO2007143631A3 - Nutraceutical treatments for diabetic and non-diabetic wound healing - Google Patents
Nutraceutical treatments for diabetic and non-diabetic wound healing Download PDFInfo
- Publication number
- WO2007143631A3 WO2007143631A3 PCT/US2007/070368 US2007070368W WO2007143631A3 WO 2007143631 A3 WO2007143631 A3 WO 2007143631A3 US 2007070368 W US2007070368 W US 2007070368W WO 2007143631 A3 WO2007143631 A3 WO 2007143631A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- diabetic
- wound healing
- resveratrol
- chlorophyll
- arginine
- Prior art date
Links
- 206010012601 diabetes mellitus Diseases 0.000 title abstract 6
- 239000002417 nutraceutical Substances 0.000 title abstract 5
- 235000021436 nutraceutical agent Nutrition 0.000 title abstract 5
- 230000029663 wound healing Effects 0.000 title abstract 3
- 238000011282 treatment Methods 0.000 title 1
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 abstract 8
- 235000002961 Aloe barbadensis Nutrition 0.000 abstract 4
- 244000186892 Aloe vera Species 0.000 abstract 4
- 239000004475 Arginine Substances 0.000 abstract 4
- VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical compound [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 abstract 4
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 abstract 4
- 241000124008 Mammalia Species 0.000 abstract 4
- 229930003268 Vitamin C Natural products 0.000 abstract 4
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 abstract 4
- 235000011399 aloe vera Nutrition 0.000 abstract 4
- 235000021028 berry Nutrition 0.000 abstract 4
- 229930002875 chlorophyll Natural products 0.000 abstract 4
- 235000019804 chlorophyll Nutrition 0.000 abstract 4
- ATNHDLDRLWWWCB-AENOIHSZSA-M chlorophyll a Chemical compound C1([C@@H](C(=O)OC)C(=O)C2=C3C)=C2N2C3=CC(C(CC)=C3C)=[N+]4C3=CC3=C(C=C)C(C)=C5N3[Mg-2]42[N+]2=C1[C@@H](CCC(=O)OC\C=C(/C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)[C@H](C)C2=C5 ATNHDLDRLWWWCB-AENOIHSZSA-M 0.000 abstract 4
- 229910052804 chromium Inorganic materials 0.000 abstract 4
- 239000011651 chromium Substances 0.000 abstract 4
- 239000000284 extract Substances 0.000 abstract 4
- 239000000126 substance Substances 0.000 abstract 4
- 235000019154 vitamin C Nutrition 0.000 abstract 4
- 239000011718 vitamin C Substances 0.000 abstract 4
- 239000011701 zinc Substances 0.000 abstract 4
- 229910052725 zinc Inorganic materials 0.000 abstract 4
- 229940016667 resveratrol Drugs 0.000 abstract 3
- 206010061218 Inflammation Diseases 0.000 abstract 2
- 230000004054 inflammatory process Effects 0.000 abstract 2
- LUKBXSAWLPMMSZ-OWOJBTEDSA-N Trans-resveratrol Chemical compound C1=CC(O)=CC=C1\C=C\C1=CC(O)=CC(O)=C1 LUKBXSAWLPMMSZ-OWOJBTEDSA-N 0.000 abstract 1
- 235000018991 trans-resveratrol Nutrition 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/30—Zinc; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
In an embodiment of the present invention, a nutraceutical formula comprising a combination of two or more substances from the group: berry extract, chromium, zinc, traws-resveratrol, /-arginine, chlorophyll, vitamin C and aloe vera combined synergistically to reduce inflammation in mammals suffering from diabetes. In another embodiment of the present invention, a nutraceutical formula comprising a combination of two or more substances from the group: berry extract, chromium, zinc, fr-απs-resveratrol, /-arginine, chlorophyll, vitamin C and aloe vera combined synergistically to enhance wound healing in mammals suffering from diabetes. In an alternative embodiment of the present invention, a nutraceutical formula comprising a combination of two or more substances from the group: berry extract, chromium, zinc, trans-resveratrol, /-arginine, chlorophyll, vitamin C and aloe vera combined synergistically to reduce inflammation in mammals not suffering from diabetes. In another embodiment of the present invention, a nutraceutical formula comprising a combination of two or more substances from the group: berry extract, chromium, zinc, trαns-resveratrol, /-arginine, chlorophyll, vitamin C and aloe vera, combined synergistically to enhance wound healing in mammals not suffering from diabetes.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12/303,033 US20100062087A1 (en) | 2006-06-02 | 2007-06-04 | Nutraceutical Treatments for Diabetic and Non-Diabetic Wound Healing |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US81074106P | 2006-06-02 | 2006-06-02 | |
US60/810,741 | 2006-06-02 | ||
US11/809,149 | 2007-05-31 | ||
US11/809,149 US7887848B2 (en) | 2006-05-31 | 2007-05-31 | Nutraceutical treatments for diabetic and non-diabetic wound healing |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2007143631A2 WO2007143631A2 (en) | 2007-12-13 |
WO2007143631A3 true WO2007143631A3 (en) | 2008-01-24 |
Family
ID=38802292
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2007/070368 WO2007143631A2 (en) | 2006-06-02 | 2007-06-04 | Nutraceutical treatments for diabetic and non-diabetic wound healing |
Country Status (1)
Country | Link |
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WO (1) | WO2007143631A2 (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007143002A2 (en) | 2006-05-31 | 2007-12-13 | Interhealth Nutraceuticals, Inc. | Nutraceutical treatments for diabetic and non-diabetic wound healing |
DE102007030931A1 (en) * | 2007-07-03 | 2009-01-08 | Birgit Riesinger | Composition containing at least one nutritive, at least one disinfecting or decontaminating and / or at least one protease inhibiting active substance and / or active substance complex |
JP2013508352A (en) * | 2009-10-19 | 2013-03-07 | ライラ ニュートラシューティカルズ | Extracts, fractions and compositions containing acetogenin and their applications |
IT1402749B1 (en) * | 2010-10-28 | 2013-09-18 | Indena Spa | COMPOSITIONS FOR THE TREATMENT OF PERIPHERAL ULCERS OF VARIOUS ORIGIN |
US20150005391A1 (en) * | 2013-06-26 | 2015-01-01 | COLE Research & Design, Inc. | Method of reducing scarring |
US20160184338A1 (en) | 2013-07-14 | 2016-06-30 | Asiros A/S | Bioactive Alkaloid Compositions and Their Medical Uses |
US10099995B2 (en) | 2015-12-24 | 2018-10-16 | Cole Research and Design, LLC | Resveratrol esters |
Citations (15)
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US5789401A (en) * | 1997-08-08 | 1998-08-04 | Nutrition 21 | High-dose chromium/biotin treatment of type II diabetes |
US5962517A (en) * | 1997-01-31 | 1999-10-05 | Murad; Howard | Pharmaceutical compositions and methods for treating acne |
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US5976568A (en) * | 1997-02-21 | 1999-11-02 | Medical Doctors' Research Institute, Inc. | Modular system of dietary supplement compositions for optimizing health benefits and methods |
US5976548A (en) * | 1994-11-08 | 1999-11-02 | Viva America Marketing, Inc. | Nutritional supplement composition and use |
US6048903A (en) * | 1994-05-03 | 2000-04-11 | Robert Toppo | Treatment for blood cholesterol with trans-resveratrol |
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-
2007
- 2007-06-04 WO PCT/US2007/070368 patent/WO2007143631A2/en active Application Filing
Patent Citations (15)
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US5976568A (en) * | 1997-02-21 | 1999-11-02 | Medical Doctors' Research Institute, Inc. | Modular system of dietary supplement compositions for optimizing health benefits and methods |
US5789401A (en) * | 1997-08-08 | 1998-08-04 | Nutrition 21 | High-dose chromium/biotin treatment of type II diabetes |
US20050196470A9 (en) * | 1998-04-03 | 2005-09-08 | Wuh Hank C | Method and composition for enhancing sexual desire |
US20030026855A1 (en) * | 1998-09-09 | 2003-02-06 | Kameneva Marina V. | Artificial blood fluids and microflow drag reducing factors for enhanced blood circulation |
US6953595B2 (en) * | 2000-06-16 | 2005-10-11 | Robert Basic | Inhibitors of apoptosis of nerve cells |
US20020155138A1 (en) * | 2001-01-19 | 2002-10-24 | Martin Katharine M. | Composition containing Hedychium extract and use thereof |
US20060039937A1 (en) * | 2003-10-31 | 2006-02-23 | Teresa Mujica-Fernaudd | Composition having antioxidant properties |
US20050196359A1 (en) * | 2004-03-03 | 2005-09-08 | D'amelio Frank S.Sr. | Method and composition for treating oral bacteria and inflammation |
US20060009099A1 (en) * | 2004-07-12 | 2006-01-12 | Closure Medical Corporation | Adhesive-containing wound closure device and method |
US20060024383A1 (en) * | 2004-07-27 | 2006-02-02 | Roger Berlin | Compositions containing policosanol and chromium and/or chromium salts and their pharmaceutical uses |
US20060062859A1 (en) * | 2004-08-05 | 2006-03-23 | Kenneth Blum | Composition and method to optimize and customize nutritional supplement formulations by measuring genetic and metabolomic contributing factors to disease diagnosis, stratification, prognosis, metabolism, and therapeutic outcomes |
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Also Published As
Publication number | Publication date |
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WO2007143631A2 (en) | 2007-12-13 |
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