WO2007140399A3 - Method of correlating analyte separation information to a biomarker - Google Patents

Method of correlating analyte separation information to a biomarker Download PDF

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Publication number
WO2007140399A3
WO2007140399A3 PCT/US2007/069959 US2007069959W WO2007140399A3 WO 2007140399 A3 WO2007140399 A3 WO 2007140399A3 US 2007069959 W US2007069959 W US 2007069959W WO 2007140399 A3 WO2007140399 A3 WO 2007140399A3
Authority
WO
WIPO (PCT)
Prior art keywords
analyte
biomarker
correlating
separation information
matrix
Prior art date
Application number
PCT/US2007/069959
Other languages
French (fr)
Other versions
WO2007140399A2 (en
Inventor
David E Clemmer
Stormy L Koeniger
Samuel I Merenbloom
Stephen J Valentine
Stephen Naylor
Original Assignee
Univ Indiana Res & Tech Corp
Predictive Physiology And Medi
David E Clemmer
Stormy L Koeniger
Samuel I Merenbloom
Stephen J Valentine
Stephen Naylor
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Indiana Res & Tech Corp, Predictive Physiology And Medi, David E Clemmer, Stormy L Koeniger, Samuel I Merenbloom, Stephen J Valentine, Stephen Naylor filed Critical Univ Indiana Res & Tech Corp
Publication of WO2007140399A2 publication Critical patent/WO2007140399A2/en
Publication of WO2007140399A3 publication Critical patent/WO2007140399A3/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

A method of correlating analyte separation information to a biomarker may comprise operating an analyte separation instrument (10) to produce a plurality of discrete analyte groups from a packet of a mixture of analytes, determining analyte intensities of each of the plurality of discrete analyte groups, creating a matrix (120) of the analyte intensities of each of the plurality of discrete analyte groups, identifying entries of the matrix that define the biomarker, and creating a map (140) correlating the biomarker to the identified entries of the matrix (120).
PCT/US2007/069959 2006-05-30 2007-05-30 Method of correlating analyte separation information to a biomarker WO2007140399A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80345406P 2006-05-30 2006-05-30
US60/803,454 2006-05-30

Publications (2)

Publication Number Publication Date
WO2007140399A2 WO2007140399A2 (en) 2007-12-06
WO2007140399A3 true WO2007140399A3 (en) 2008-01-24

Family

ID=38779432

Family Applications (3)

Application Number Title Priority Date Filing Date
PCT/US2007/069963 WO2007140401A2 (en) 2006-05-30 2007-05-30 Method of operating an analyte separation instrument
PCT/US2007/069959 WO2007140399A2 (en) 2006-05-30 2007-05-30 Method of correlating analyte separation information to a biomarker
PCT/US2007/069960 WO2007140400A2 (en) 2006-05-30 2007-05-30 Method of operating an ion separation instrument

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PCT/US2007/069963 WO2007140401A2 (en) 2006-05-30 2007-05-30 Method of operating an analyte separation instrument

Family Applications After (1)

Application Number Title Priority Date Filing Date
PCT/US2007/069960 WO2007140400A2 (en) 2006-05-30 2007-05-30 Method of operating an ion separation instrument

Country Status (1)

Country Link
WO (3) WO2007140401A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6290452B2 (en) * 2014-12-24 2018-03-07 株式会社日立ハイテクノロジーズ Mass spectrometer
CN110687565B (en) * 2019-09-20 2023-01-20 天津大学 Rapid calculation method for photo-generated charge of X-ray detector

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040259265A1 (en) * 2002-09-27 2004-12-23 Ulrich Bonne Phased micro analyzer IV
US20050244980A1 (en) * 2003-12-10 2005-11-03 The Regents Of The University Of California On-line gas chromatographic analysis of airborne particles
US20050287679A1 (en) * 2002-03-11 2005-12-29 Pawliszyn Janusz B Calibration procedure for investigating biological systems

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2299985A (en) * 1995-04-18 1996-10-23 Beeson & Sons Ltd Child resistant closure assemblies
US6960761B2 (en) * 1997-06-02 2005-11-01 Advanced Research & Technology Institute Instrument for separating ions in time as functions of preselected ion mobility and ion mass
US6323482B1 (en) * 1997-06-02 2001-11-27 Advanced Research And Technology Institute, Inc. Ion mobility and mass spectrometer
US6521887B1 (en) * 1999-05-12 2003-02-18 The Regents Of The University Of California Time-of-flight ion mass spectrograph
US6992283B2 (en) * 2003-06-06 2006-01-31 Micromass Uk Limited Mass spectrometer
WO2005106450A1 (en) * 2004-04-28 2005-11-10 Sionex Corporation System and method for ion species analysis with enhanced condition control and data interpretation using differential mobility spectrometers

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050287679A1 (en) * 2002-03-11 2005-12-29 Pawliszyn Janusz B Calibration procedure for investigating biological systems
US20040259265A1 (en) * 2002-09-27 2004-12-23 Ulrich Bonne Phased micro analyzer IV
US20050244980A1 (en) * 2003-12-10 2005-11-03 The Regents Of The University Of California On-line gas chromatographic analysis of airborne particles

Also Published As

Publication number Publication date
WO2007140401A2 (en) 2007-12-06
WO2007140399A2 (en) 2007-12-06
WO2007140400A2 (en) 2007-12-06
WO2007140401A3 (en) 2008-12-24
WO2007140400A3 (en) 2008-05-08

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