WO2007138577A3 - Methods of generating a neural tissue using muscle-derived cells - Google Patents

Methods of generating a neural tissue using muscle-derived cells Download PDF

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Publication number
WO2007138577A3
WO2007138577A3 PCT/IL2007/000637 IL2007000637W WO2007138577A3 WO 2007138577 A3 WO2007138577 A3 WO 2007138577A3 IL 2007000637 W IL2007000637 W IL 2007000637W WO 2007138577 A3 WO2007138577 A3 WO 2007138577A3
Authority
WO
WIPO (PCT)
Prior art keywords
muscle
generating
methods
derived cells
neural tissue
Prior art date
Application number
PCT/IL2007/000637
Other languages
French (fr)
Other versions
WO2007138577A2 (en
Inventor
David Yaffe
Rachel Sarig
Uri Nudel
Ora Fuchs
Original Assignee
Yeda Res & Dev
David Yaffe
Rachel Sarig
Uri Nudel
Ora Fuchs
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Res & Dev, David Yaffe, Rachel Sarig, Uri Nudel, Ora Fuchs filed Critical Yeda Res & Dev
Publication of WO2007138577A2 publication Critical patent/WO2007138577A2/en
Publication of WO2007138577A3 publication Critical patent/WO2007138577A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/34—Muscles; Smooth muscle cells; Heart; Cardiac stem cells; Myoblasts; Myocytes; Cardiomyocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0658—Skeletal muscle cells, e.g. myocytes, myotubes, myoblasts
    • C12N5/0659—Satellite cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells

Abstract

Use of human myogenic satellite cells for the manufacture of a medicament identified for treating a medical condition of the CNS is provided.
PCT/IL2007/000637 2006-05-25 2007-05-27 Methods of generating a neural tissue using muscle-derived cells WO2007138577A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80811206P 2006-05-25 2006-05-25
US60/808,112 2006-05-25

Publications (2)

Publication Number Publication Date
WO2007138577A2 WO2007138577A2 (en) 2007-12-06
WO2007138577A3 true WO2007138577A3 (en) 2009-04-23

Family

ID=38779083

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2007/000637 WO2007138577A2 (en) 2006-05-25 2007-05-27 Methods of generating a neural tissue using muscle-derived cells

Country Status (1)

Country Link
WO (1) WO2007138577A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5657674B2 (en) 2010-08-17 2015-01-21 テルモ株式会社 Graft evaluation method

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030124102A1 (en) * 2001-09-17 2003-07-03 Rudnicki Michael A. Pax-encoding vector and use thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030124102A1 (en) * 2001-09-17 2003-07-03 Rudnicki Michael A. Pax-encoding vector and use thereof

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
ALESSANDRI ET AL.: "Isolation and culture of human muscle-derived stem cells able to differentiate into myogenic and neurogenic cell lineages.", LANCET, vol. 364, 2004, pages 1872 - 1883 *
GOLDRING ET AL.: "Muscle stem cells.", J PATHOL, vol. 197, 2002, pages 457 - 467 *
KRABBE ET AL.: "Neural transdifferentiation of mesenchymal stem cells - a critical review.", APMIS, vol. 113, 2005, pages 831 - 844 *
MIGNON ET AL.: "Transplantation of Multipotent cells extracted from adult skeletal muscles into the subventricular zone of adult rats.", THE J COMP NEUROL, vol. 491, 2005, pages 96 - 108 *
ROMERO-RAMOS ET AL.: "Neuronal differentiation of stem cells isolated from adult muscle.", JOUR NEUROSC RES, vol. 69, 2002, pages 894 - 907 *
SCHULTZ ET AL.: "Human stem cells isolated from adult skeletal muscle differentiate into neural phenotypes.", J NEUROSC METH, vol. 152, 2006, pages 144 - 155 *
STEFFEL ET AL.: "Migration and differentiation of myogenic precursors following transplantation into the developing rat brain.", STEM CELLS, vol. 21, 2003, pages 181 - 189 *

Also Published As

Publication number Publication date
WO2007138577A2 (en) 2007-12-06

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