WO2007138557A3 - Compositions pharmaceutiques à unités multiples à libération contrôlée - Google Patents

Compositions pharmaceutiques à unités multiples à libération contrôlée Download PDF

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Publication number
WO2007138557A3
WO2007138557A3 PCT/IB2007/052037 IB2007052037W WO2007138557A3 WO 2007138557 A3 WO2007138557 A3 WO 2007138557A3 IB 2007052037 W IB2007052037 W IB 2007052037W WO 2007138557 A3 WO2007138557 A3 WO 2007138557A3
Authority
WO
WIPO (PCT)
Prior art keywords
controlled
multiple unit
pharmaceutical compositions
release multiple
unit pharmaceutical
Prior art date
Application number
PCT/IB2007/052037
Other languages
English (en)
Other versions
WO2007138557A2 (fr
Inventor
Sankar Ramakrishnan
Narayanan Badri Viswanathan
Ashok Rampal
Rajesh S Shear
Sumit Madan
Original Assignee
Ranbaxy Lab Ltd
Sankar Ramakrishnan
Narayanan Badri Viswanathan
Ashok Rampal
Rajesh S Shear
Sumit Madan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Lab Ltd, Sankar Ramakrishnan, Narayanan Badri Viswanathan, Ashok Rampal, Rajesh S Shear, Sumit Madan filed Critical Ranbaxy Lab Ltd
Publication of WO2007138557A2 publication Critical patent/WO2007138557A2/fr
Publication of WO2007138557A3 publication Critical patent/WO2007138557A3/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets

Landscapes

  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)

Abstract

La présente invention concerne une formulation à unités multiples et à libération contrôlée et des procédés d'élaboration correspondants. La formulation comprend (1) une unité noyau d'un matériau inerte; et (ii) une couche d'enrobage comprenant un mélange d'un principe actif pharmaceutique, d'au moins un polymère insoluble dans l'eau, d'au moins un polymère hydrophile, et d'au moins un composant hydrosoluble.
PCT/IB2007/052037 2006-05-30 2007-05-30 Compositions pharmaceutiques à unités multiples à libération contrôlée WO2007138557A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1308/DEL/2006 2006-05-30
IN1308DE2006 2006-05-30

Publications (2)

Publication Number Publication Date
WO2007138557A2 WO2007138557A2 (fr) 2007-12-06
WO2007138557A3 true WO2007138557A3 (fr) 2008-02-14

Family

ID=38645782

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2007/052037 WO2007138557A2 (fr) 2006-05-30 2007-05-30 Compositions pharmaceutiques à unités multiples à libération contrôlée

Country Status (1)

Country Link
WO (1) WO2007138557A2 (fr)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5049374A (en) * 1989-11-28 1991-09-17 Dansereau Richard J Oral (coated bead) dosage form for sodium iodide I-131
DE4400295A1 (de) * 1993-01-12 1994-07-14 Freunt Ind Co Ltd Sphärisches Granulum, Verfahren zum Herstellen desselben und Arzneimittelzubereitung unter Einsatz des Granulums
WO2000000179A1 (fr) * 1998-06-27 2000-01-06 Won Jin Biopharma Co., Ltd. Preparation a dispersion solide d'un medicament faiblement hydrosoluble contenant de l'huile, un acide gras ou leurs melanges
US6221396B1 (en) * 1998-07-17 2001-04-24 Development Center For Biotechnology Oral cisapride dosage forms with an extended duration

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5049374A (en) * 1989-11-28 1991-09-17 Dansereau Richard J Oral (coated bead) dosage form for sodium iodide I-131
DE4400295A1 (de) * 1993-01-12 1994-07-14 Freunt Ind Co Ltd Sphärisches Granulum, Verfahren zum Herstellen desselben und Arzneimittelzubereitung unter Einsatz des Granulums
WO2000000179A1 (fr) * 1998-06-27 2000-01-06 Won Jin Biopharma Co., Ltd. Preparation a dispersion solide d'un medicament faiblement hydrosoluble contenant de l'huile, un acide gras ou leurs melanges
US6221396B1 (en) * 1998-07-17 2001-04-24 Development Center For Biotechnology Oral cisapride dosage forms with an extended duration

Also Published As

Publication number Publication date
WO2007138557A2 (fr) 2007-12-06

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