WO2007135123A3 - Mirtazapine for the treatment of neuropathic pain - Google Patents

Mirtazapine for the treatment of neuropathic pain Download PDF

Info

Publication number
WO2007135123A3
WO2007135123A3 PCT/EP2007/054872 EP2007054872W WO2007135123A3 WO 2007135123 A3 WO2007135123 A3 WO 2007135123A3 EP 2007054872 W EP2007054872 W EP 2007054872W WO 2007135123 A3 WO2007135123 A3 WO 2007135123A3
Authority
WO
WIPO (PCT)
Prior art keywords
treatment
neuropathic pain
mirtazapine
administering
medicine
Prior art date
Application number
PCT/EP2007/054872
Other languages
French (fr)
Other versions
WO2007135123A2 (en
Inventor
Andrea Houghton
Gerardus Stephanus Franc Ruigt
Original Assignee
Organon Nv
Andrea Houghton
Gerardus Stephanus Franc Ruigt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Organon Nv, Andrea Houghton, Gerardus Stephanus Franc Ruigt filed Critical Organon Nv
Priority to CA002651607A priority Critical patent/CA2651607A1/en
Priority to EP07729316A priority patent/EP2026814A2/en
Priority to MX2008014287A priority patent/MX2008014287A/en
Priority to JP2009511495A priority patent/JP2009537601A/en
Publication of WO2007135123A2 publication Critical patent/WO2007135123A2/en
Publication of WO2007135123A3 publication Critical patent/WO2007135123A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

This invention relates to a method of treatment of neuropathic pain comprising administering to a subject in need of treatment for neuropathic pain a therapeutically effective dose of S(+)-mirtazapine and the use of S(+)-mirtazapine for the manufacture of a medicine for the treatment of neuropathic pain and a pharmaceutical composition for the treatment of neuropathic pain, comprising S(+)-mirtazapine.
PCT/EP2007/054872 2006-05-22 2007-05-21 Mirtazapine for the treatment of neuropathic pain WO2007135123A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002651607A CA2651607A1 (en) 2006-05-22 2007-05-21 Mirtazapine for the treatment of neuropathic pain
EP07729316A EP2026814A2 (en) 2006-05-22 2007-05-21 Mirtazapine for the treatment of neuropathic pain
MX2008014287A MX2008014287A (en) 2006-05-22 2007-05-21 Mirtazapine for the treatment of neuropathic pain.
JP2009511495A JP2009537601A (en) 2006-05-22 2007-05-21 Mirtazapine for the treatment of neuropathic pain

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06114316 2006-05-22
EP06114316.0 2006-05-22

Publications (2)

Publication Number Publication Date
WO2007135123A2 WO2007135123A2 (en) 2007-11-29
WO2007135123A3 true WO2007135123A3 (en) 2008-03-13

Family

ID=37006417

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2007/054872 WO2007135123A2 (en) 2006-05-22 2007-05-21 Mirtazapine for the treatment of neuropathic pain

Country Status (8)

Country Link
EP (1) EP2026814A2 (en)
JP (1) JP2009537601A (en)
AR (1) AR061046A1 (en)
CA (1) CA2651607A1 (en)
MX (1) MX2008014287A (en)
PE (1) PE20080455A1 (en)
TW (1) TW200808804A (en)
WO (1) WO2007135123A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6452954B2 (en) * 2013-05-16 2019-01-16 国立大学法人千葉大学 Cancer metastasis inhibitor
CA3013771C (en) 2015-02-27 2024-01-02 Kindred Biosciences, Inc. Stimulation of appetite, management of weight loss, and treatment of anorexia in dogs and cats

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030096805A1 (en) * 2000-09-26 2003-05-22 Wang Ging Kuo Antidepressants and their analogues as long-acting local anesthetics and analgesics
US20030105083A1 (en) * 2000-01-19 2003-06-05 Andrews John Stuart Drug combination for the treatment of depression and related disorders comprising mirtazapine
WO2005005410A1 (en) * 2003-07-10 2005-01-20 Akzo Nobel N.V. A method for the preparation of enantiomerically pure mirtazapine
WO2005102352A1 (en) * 2004-04-21 2005-11-03 N.V. Organon Pharmaceutical composition comprising a salt of mirtazapine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6211171B1 (en) * 1998-05-19 2001-04-03 Dalhousie University Use of antidepressants for local analgesia

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030105083A1 (en) * 2000-01-19 2003-06-05 Andrews John Stuart Drug combination for the treatment of depression and related disorders comprising mirtazapine
US20030096805A1 (en) * 2000-09-26 2003-05-22 Wang Ging Kuo Antidepressants and their analogues as long-acting local anesthetics and analgesics
WO2005005410A1 (en) * 2003-07-10 2005-01-20 Akzo Nobel N.V. A method for the preparation of enantiomerically pure mirtazapine
WO2005102352A1 (en) * 2004-04-21 2005-11-03 N.V. Organon Pharmaceutical composition comprising a salt of mirtazapine

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
"P.2.029 Mirtazapine greatly alleviates the symptoms of fibromyalgia", EUROPEAN NEUROPSYCHOPHARMACOLOGY, ELSEVIER SCIENCE PUBLISHERS BV, AMSTERDAM, NL, vol. 15, 2005, pages S403 - S404, XP005556659, ISSN: 0924-977X *
BENDTSEN LARS ET AL: "Mirtazapine is effective in the prophylactic treatment of chronic tension-type headache.", NEUROLOGY. 25 MAY 2004, vol. 62, no. 10, 25 May 2004 (2004-05-25), pages 1706 - 1711, XP009073028, ISSN: 1526-632X *
MATTIA C ET AL: "NEW ANTIDEPRESSANTS IN THE TREATMENT OF NEUROPATHIC PAIN - A REVIEW", MINERVA ANESTESIOLOGICA, XX, XX, vol. 68, no. 3, March 2002 (2002-03-01), pages 105 - 114, XP009054549, ISSN: 0375-9393 *

Also Published As

Publication number Publication date
PE20080455A1 (en) 2008-06-25
JP2009537601A (en) 2009-10-29
WO2007135123A2 (en) 2007-11-29
EP2026814A2 (en) 2009-02-25
TW200808804A (en) 2008-02-16
MX2008014287A (en) 2008-11-18
AR061046A1 (en) 2008-07-30
CA2651607A1 (en) 2007-11-29

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