WO2007129169A3 - Cox- ii inhibitors for improving reproductive success in a female animal - Google Patents

Cox- ii inhibitors for improving reproductive success in a female animal Download PDF

Info

Publication number
WO2007129169A3
WO2007129169A3 PCT/IB2007/001082 IB2007001082W WO2007129169A3 WO 2007129169 A3 WO2007129169 A3 WO 2007129169A3 IB 2007001082 W IB2007001082 W IB 2007001082W WO 2007129169 A3 WO2007129169 A3 WO 2007129169A3
Authority
WO
WIPO (PCT)
Prior art keywords
cox
inhibitors
female animal
reproductive success
improving reproductive
Prior art date
Application number
PCT/IB2007/001082
Other languages
French (fr)
Other versions
WO2007129169A2 (en
Inventor
Leopold Franz Goetze
Anthony Paul Ricketts
Original Assignee
Pfizer Ltd
Leopold Franz Goetze
Anthony Paul Ricketts
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Ltd, Leopold Franz Goetze, Anthony Paul Ricketts filed Critical Pfizer Ltd
Publication of WO2007129169A2 publication Critical patent/WO2007129169A2/en
Publication of WO2007129169A3 publication Critical patent/WO2007129169A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Inhibitors of COX-II are useful for improving reproductive success in female animals.
PCT/IB2007/001082 2006-05-04 2007-04-17 Cox- ii inhibitors for improving reproductive success in a female animal WO2007129169A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US79816206P 2006-05-04 2006-05-04
US60/798,162 2006-05-04

Publications (2)

Publication Number Publication Date
WO2007129169A2 WO2007129169A2 (en) 2007-11-15
WO2007129169A3 true WO2007129169A3 (en) 2008-03-20

Family

ID=38566286

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2007/001082 WO2007129169A2 (en) 2006-05-04 2007-04-17 Cox- ii inhibitors for improving reproductive success in a female animal

Country Status (4)

Country Link
JP (1) JP2007297385A (en)
AR (1) AR060837A1 (en)
TW (1) TW200812617A (en)
WO (1) WO2007129169A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100922519B1 (en) * 2008-11-12 2009-10-20 대원제약주식회사 Pharmaceutical formulation having improved dissolution rate and stability for oral administration containing pelubiprofen
KR101561345B1 (en) * 2013-10-17 2015-10-16 대원제약주식회사 Controlled-release pharmaceutical composition of propionic acid derivatives
JP6867000B2 (en) * 2016-10-24 2021-04-28 国立研究開発法人農業・食品産業技術総合研究機構 Fertility promoter

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
ELLI M ET AL: "Effect of a single dose of ibuprofen lysinate before embryo transfer on pregnancy rates in cows.", REPRODUCTION (CAMBRIDGE, ENGLAND) JAN 2001, vol. 121, no. 1, January 2001 (2001-01-01), pages 151 - 154, XP002462902, ISSN: 1470-1626 *
FISCHER CLAUDIA ET AL: "Postpartum reproductive failure in cattle: Is the examination of the gene expression in the bovine endometrium a way to success ?", BERLINER UND MUNCHENER TIERARZTLICHE WOCHENSCHRIFT, vol. 119, no. 5-6, May 2006 (2006-05-01), pages 197 - 202, XP009093888, ISSN: 0005-9366 *
GUZELOGLU A ET AL: "Effect of timely flunixin meglumine treatment on pregnancy rates in Holstein heifers", REPRODUCTION FERTILITY AND DEVELOPMENT, vol. 18, no. 1-2, January 2006 (2006-01-01), & 32ND ANNUAL CONFERENCE OF THE INTERNATIONAL-EMBRYO-TRANSFER-SOCIETY; ORLANDO, FL, USA; JANUARY 07 -11, 2006, pages 183, XP009093961, ISSN: 1031-3613 *
LOONEY ET AL: "Improving fertility in beef cow recipients", THERIOGENOLOGY, LOS ALTOS, CA, US, vol. 65, no. 1, 7 January 2006 (2006-01-07), pages 201 - 209, XP005179771, ISSN: 0093-691X *
MOON H S ET AL: "Treatment with piroxicam before embryo transfer increases the pregnancy rate after in vitro fertilization and embryo transfer", FERTILITY AND STERILITY, ELSEVIER SCIENCE INC, NEW YORK, NY, US, vol. 82, no. 4, October 2004 (2004-10-01), pages 816 - 820, XP004598841, ISSN: 0015-0282 *
RISCO C A ET AL: "Clinical mastitis associated with abortion in dairy cows.", JOURNAL OF DAIRY SCIENCE AUG 1999, vol. 82, no. 8, August 1999 (1999-08-01), pages 1684 - 1689, XP002462901, ISSN: 0022-0302 *
THUN R ET AL: "Carprofen in veterinary medicine. II. Inhibitory effect on the release of PGF2 alpha in the early postpartum cow.", SCHWEIZER ARCHIV FÜR TIERHEILKUNDE 1989, vol. 131, no. 4, 1989, pages 205 - 212, XP009093893, ISSN: 0036-7281 *
VANGROENWEGHE F ET AL: "Effect of carprofen treatment following experimentally induced Escherichia coli mastitis in primiparous cows.", JOURNAL OF DAIRY SCIENCE JUL 2005, vol. 88, no. 7, July 2005 (2005-07-01), pages 2361 - 2376, XP002462900, ISSN: 1525-3198 *

Also Published As

Publication number Publication date
TW200812617A (en) 2008-03-16
AR060837A1 (en) 2008-07-16
WO2007129169A2 (en) 2007-11-15
JP2007297385A (en) 2007-11-15

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