WO2007127376A3 - Computer-implemented model of the central nervous system - Google Patents

Computer-implemented model of the central nervous system Download PDF

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Publication number
WO2007127376A3
WO2007127376A3 PCT/US2007/010249 US2007010249W WO2007127376A3 WO 2007127376 A3 WO2007127376 A3 WO 2007127376A3 US 2007010249 W US2007010249 W US 2007010249W WO 2007127376 A3 WO2007127376 A3 WO 2007127376A3
Authority
WO
WIPO (PCT)
Prior art keywords
brainstem
spinal cord
nervous system
central nervous
real
Prior art date
Application number
PCT/US2007/010249
Other languages
French (fr)
Other versions
WO2007127376A2 (en
Inventor
Sungho Jo
Steven G Massaquoi
Zhi-Hong Mao
Original Assignee
Massachusetts Inst Technology
Sungho Jo
Steven G Massaquoi
Zhi-Hong Mao
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2006/031876 external-priority patent/WO2007022204A2/en
Application filed by Massachusetts Inst Technology, Sungho Jo, Steven G Massaquoi, Zhi-Hong Mao filed Critical Massachusetts Inst Technology
Priority to PCT/US2007/020944 priority Critical patent/WO2008042268A2/en
Publication of WO2007127376A2 publication Critical patent/WO2007127376A2/en
Publication of WO2007127376A3 publication Critical patent/WO2007127376A3/en
Priority to US12/258,893 priority patent/US20090106007A1/en
Priority to US12/412,494 priority patent/US20090182697A1/en

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Classifications

    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06NCOMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N3/00Computing arrangements based on biological models
    • G06N3/004Artificial life, i.e. computing arrangements simulating life

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  • Engineering & Computer Science (AREA)
  • Theoretical Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Computing Systems (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Computational Linguistics (AREA)
  • Data Mining & Analysis (AREA)
  • Evolutionary Computation (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Artificial Intelligence (AREA)
  • General Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Mathematical Physics (AREA)
  • Software Systems (AREA)
  • Health & Medical Sciences (AREA)
  • Electrotherapy Devices (AREA)
  • Instructional Devices (AREA)

Abstract

A computer-implemented model of the central nervous system includes at least one of a basal ganglia portion, a cerebral cortex portion coupled to the basal ganglia portion, a cerebellum portion coupled to the cerebral cortex, or a brainstem/spinal cord portion coupled to at least one of the cerebral cortex portion, the cerebellum portion, or the basal ganglia portion. Each one of the basal ganglia portion, the cerebral cortex portion, and the cerebellum portion is comprised of respective elements representative of real neuroanatomical structures of a central nervous system and the respective elements are adapted to perform functions representative of real neuroanatomical functions of the central nervous system. The brainstem/spinal cord portion is comprised of brainstem/spinal cord elements representative of real neuroanatomical structures of a brainstem/spinal cord. The brainstem/spinal cord elements can perform functions representative of real neuroanatomical functions of the brainstem/spinal cord.
PCT/US2007/010249 2005-08-15 2007-04-27 Computer-implemented model of the central nervous system WO2007127376A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
PCT/US2007/020944 WO2008042268A2 (en) 2006-09-28 2007-09-28 Computer-implemented model of the central nervous system
US12/258,893 US20090106007A1 (en) 2005-08-15 2008-10-27 Computer-Implemented Model of the Central Nervous System
US12/412,494 US20090182697A1 (en) 2005-08-15 2009-03-27 Computer-Implemented Model of the Central Nervous System

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US74580106P 2006-04-27 2006-04-27
US60/745,801 2006-04-27
USPCT/US2006/031876 2006-08-15
PCT/US2006/031876 WO2007022204A2 (en) 2005-08-15 2006-08-15 Computer-implemented model of the central nervous system

Related Parent Applications (2)

Application Number Title Priority Date Filing Date
PCT/US2006/031876 Continuation WO2007022204A2 (en) 2005-08-15 2006-08-15 Computer-implemented model of the central nervous system
PCT/US2006/031876 Continuation-In-Part WO2007022204A2 (en) 2005-08-15 2006-08-15 Computer-implemented model of the central nervous system

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US12/258,893 Continuation US20090106007A1 (en) 2005-08-15 2008-10-27 Computer-Implemented Model of the Central Nervous System

Publications (2)

Publication Number Publication Date
WO2007127376A2 WO2007127376A2 (en) 2007-11-08
WO2007127376A3 true WO2007127376A3 (en) 2007-12-27

Family

ID=38556425

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/010249 WO2007127376A2 (en) 2005-08-15 2007-04-27 Computer-implemented model of the central nervous system

Country Status (1)

Country Link
WO (1) WO2007127376A2 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993015448A1 (en) * 1992-01-31 1993-08-05 Honeywell Inc. Neuro-pid controller
WO1994017457A1 (en) * 1993-01-22 1994-08-04 Honeywell Inc. Parameterized neurocontrollers
EP1552908A1 (en) * 2002-10-11 2005-07-13 Fujitsu Limited Robot control algorithm construction device, robot control algorithm construction program, robot control device, robot control program, and robot

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993015448A1 (en) * 1992-01-31 1993-08-05 Honeywell Inc. Neuro-pid controller
WO1994017457A1 (en) * 1993-01-22 1994-08-04 Honeywell Inc. Parameterized neurocontrollers
EP1552908A1 (en) * 2002-10-11 2005-07-13 Fujitsu Limited Robot control algorithm construction device, robot control algorithm construction program, robot control device, robot control program, and robot

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
AYASO O ET AL: "Coarse- gain recurrent integrator model for sensorimotor cortical command generation", PROCEEDINGS OF THE 2002 AMERICAN CONTROL CONFERENCE. ACC. ANCHORAGE, AL, MAY 8 - 10, 2002, AMERICAN CONTROL CONFERENCE, NEW YORK, NY : IEEE, US, vol. VOL. 1 OF 6, 8 May 2002 (2002-05-08), pages 1736 - 1741, XP010596329, ISBN: 0-7803-7298-0 *
MAO, ZHI-HONG: "Modeling the role of the basal ganglia in motor control and motor programming, Thesis (Ph. D.)--Harvard-MIT Division of Health Sciences and Technology, 2005.", September 2005, MASSACHUSETTS INSTITUTE OF TECHNOLOGY, US, XP002454350 *
SUNGHO JO ET AL: "A model of cerebellum stabilized and scheduled hybrid long-loop control of upright balance", BIOLOGICAL CYBERNETICS SPRINGER-VERLAG GERMANY, vol. 91, no. 3, 14 September 2004 (2004-09-14), pages 188 - 202, XP002454167, ISSN: 0340-1200 *
SUNGHO JO ET AL: "A model of cerebrocerebello-spinomuscular interaction in the sagittal control of human walking", BIOLOGICAL CYBERNETICS ; ADVANCES IN COMPUTATIONAL NEUROSCIENCE, SPRINGER-VERLAG, BE, vol. 96, no. 3, 24 November 2006 (2006-11-24), pages 279 - 307, XP019491647, ISSN: 1432-0770 *

Also Published As

Publication number Publication date
WO2007127376A2 (en) 2007-11-08

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