WO2007126865A3 - Leukotriene antagonists via nasal drug delivery - Google Patents

Leukotriene antagonists via nasal drug delivery Download PDF

Info

Publication number
WO2007126865A3
WO2007126865A3 PCT/US2007/007650 US2007007650W WO2007126865A3 WO 2007126865 A3 WO2007126865 A3 WO 2007126865A3 US 2007007650 W US2007007650 W US 2007007650W WO 2007126865 A3 WO2007126865 A3 WO 2007126865A3
Authority
WO
WIPO (PCT)
Prior art keywords
leukotriene antagonists
drug delivery
via nasal
nasal drug
antagonists via
Prior art date
Application number
PCT/US2007/007650
Other languages
French (fr)
Other versions
WO2007126865A2 (en
Inventor
Jay S Trivedi
Robert P Quinn
Original Assignee
Patrin Pharma
Jay S Trivedi
Robert P Quinn
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Patrin Pharma, Jay S Trivedi, Robert P Quinn filed Critical Patrin Pharma
Publication of WO2007126865A2 publication Critical patent/WO2007126865A2/en
Publication of WO2007126865A3 publication Critical patent/WO2007126865A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Otolaryngology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention provides pharmaceutical compositions for leukotriene antagonists for nasal and ocular delivery routes. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory and cytoprotective agents. They are also useful in treating hepatitis, endotoxemia and psoriasis.
PCT/US2007/007650 2006-03-30 2007-03-27 Leukotriene antagonists via nasal drug delivery WO2007126865A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78739006P 2006-03-30 2006-03-30
US60/787,390 2006-03-30

Publications (2)

Publication Number Publication Date
WO2007126865A2 WO2007126865A2 (en) 2007-11-08
WO2007126865A3 true WO2007126865A3 (en) 2008-11-06

Family

ID=38656035

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/007650 WO2007126865A2 (en) 2006-03-30 2007-03-27 Leukotriene antagonists via nasal drug delivery

Country Status (1)

Country Link
WO (1) WO2007126865A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2640355A1 (en) * 2010-11-16 2013-09-25 Lupin Limited Stable oral pharmaceutical compositions of montelukast
KR101555908B1 (en) * 2013-12-19 2015-09-25 한미약품 주식회사 Liquid formulation comprising montelukast or pharmaceutically acceptable salt thereof and method for preparing the same
CN103720672B (en) * 2014-01-26 2016-03-16 新疆特丰药业股份有限公司 Montelukast sodium chewable tablet and direct powder compression preparation method thereof
US9717684B2 (en) * 2014-04-25 2017-08-01 R.P. Scherer Technologies, Llc Stable montelukast solution
KR102391494B1 (en) * 2014-05-07 2022-04-28 한미약품 주식회사 Liquid formulation with enhanced stability comprising montelukast or pharmaceutically acceptable salt thereof and method for preparing same
US10548837B1 (en) * 2016-05-04 2020-02-04 Taro Pharmaceutical Industries Ltd. Topical montelukast for treatment of atopic dermatitis
SG11201911841PA (en) * 2017-07-05 2020-01-30 Jiangyin Mucocare Pharmaceutical Co Ltd Topical formulations comprising montelukast and combinations with mussel adhesive proteins
EP3908284A4 (en) * 2019-01-10 2023-02-08 EnliTISA (Shanghai) Pharmaceutical Co., Ltd. New formulations containing leukotriene receptor antagonists
NZ790643A (en) * 2020-02-03 2023-05-26 Taro Pharma Ind Topical montelukast formulations

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020061281A1 (en) * 1999-07-06 2002-05-23 Osbakken Robert S. Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis
US6436924B2 (en) * 2000-02-17 2002-08-20 Asta Medica Ag Antihistamine leukotriene combinations
US20020151562A1 (en) * 2001-02-05 2002-10-17 Seligman Morton J. Compositions and methods for treating allergic fungal sinusitis

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020061281A1 (en) * 1999-07-06 2002-05-23 Osbakken Robert S. Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis
US6436924B2 (en) * 2000-02-17 2002-08-20 Asta Medica Ag Antihistamine leukotriene combinations
US20020151562A1 (en) * 2001-02-05 2002-10-17 Seligman Morton J. Compositions and methods for treating allergic fungal sinusitis

Also Published As

Publication number Publication date
WO2007126865A2 (en) 2007-11-08

Similar Documents

Publication Publication Date Title
WO2007126865A3 (en) Leukotriene antagonists via nasal drug delivery
WO2004093795A3 (en) Compositions for delivery of drug combinations
WO2008017381A8 (en) Arylaminoaryl-alkyl-substituted imidazolidine-2,4-diones, processes for preparing them, medicaments comprising these compounds, and their use
WO2008145681A3 (en) Ccr2 receptor antagonists and uses thereof
WO2009071690A3 (en) 5,6-disubstituted oxindole-derivatives and use thereof for treating vasopressine-dependent diseases
HK1122508A1 (en) Nanoparticles for protein drug delivery
WO2008021368A3 (en) Compositions and methods for neuroprotection
WO2008138755A3 (en) Pharmaceutical compositions for poorly soluble drugs
WO2008031556A3 (en) 2 amino-pyrimidine derivatives as h4 receptor antagonists, processes for preparing them and their use in pharmaceutical compositions
TW200700414A (en) Novel pharmaceutical compounds
IL229304A (en) 1',3'-disubstituted- 4- phenyl- 3, 4, 5, 6 -tetrahydro-2h, 1'h - [1, 4'] bipyridinyl- 2'-ones, pharmaceutical compositions comprising them and uses thereof
WO2009027644A8 (en) Compositions for the treatment of neoplastic diseases
WO2007092329A3 (en) Pharmaceutical compositions for treating depression, anxiety and neurodegenerative disorders
WO2007057714A3 (en) Pharmaceutical compositions comprising methotrexate
WO2007118653A3 (en) Nanoparticle containing nicotine and/or cotinine, dispersions and use thereof
WO2010031184A8 (en) Azaindole derivatives as crth2 receptor antagonists
WO2007120574A3 (en) Diaryl substituted alkanes
WO2006048248A3 (en) Novel anthranilamide pyridinureas as vegf receptor kinase imhibitors
WO2007107706A3 (en) Dimers of heterocyclic compounds for the treatment of copd
WO2007065595A3 (en) Xanthine derivatives, processes for preparing them and their uses
WO2003028696A3 (en) Compositions for delivery of drug combinations
WO2010121164A3 (en) 1,4-benzodiazepinone compounds and their use in treating cancer
WO2010067078A8 (en) 3,6-disubstituted xanthylium salts
TWI315305B (en) Piperidin-4-yl-amide derivatives,pharmaceutical compositions comprising the same,process for preparing the same and the use thereof
WO2006097617A3 (en) Novel dihydropyrimidine derivatives and their use as anti-cancer agents

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 07754204

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 07754204

Country of ref document: EP

Kind code of ref document: A2