WO2007121883A3 - 1,4:3,6-dianhydromannitol derivatives and use thereof - Google Patents

1,4:3,6-dianhydromannitol derivatives and use thereof Download PDF

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Publication number
WO2007121883A3
WO2007121883A3 PCT/EP2007/003332 EP2007003332W WO2007121883A3 WO 2007121883 A3 WO2007121883 A3 WO 2007121883A3 EP 2007003332 W EP2007003332 W EP 2007003332W WO 2007121883 A3 WO2007121883 A3 WO 2007121883A3
Authority
WO
WIPO (PCT)
Prior art keywords
dianhydromannitol
derivatives
amongst
formulae
things
Prior art date
Application number
PCT/EP2007/003332
Other languages
German (de)
French (fr)
Other versions
WO2007121883A2 (en
Inventor
Lutz Mueller-Kuhrt
Hajo Schiewe
Stefan Schunk
Herbert Waldmann
Heino Prinz
Harald Schwalbe
Krishna Saxena
Original Assignee
Analyticon Discovery Gmbh
Lutz Mueller-Kuhrt
Hajo Schiewe
Stefan Schunk
Herbert Waldmann
Heino Prinz
Harald Schwalbe
Krishna Saxena
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Analyticon Discovery Gmbh, Lutz Mueller-Kuhrt, Hajo Schiewe, Stefan Schunk, Herbert Waldmann, Heino Prinz, Harald Schwalbe, Krishna Saxena filed Critical Analyticon Discovery Gmbh
Publication of WO2007121883A2 publication Critical patent/WO2007121883A2/en
Publication of WO2007121883A3 publication Critical patent/WO2007121883A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Molecular Biology (AREA)
  • Obesity (AREA)
  • Biochemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

The invention relates, amongst other things, to the use of 1,4:3,6-dianhydromannitol derivatives of formulae (Ia) - (Id) as therapeutic agents.
PCT/EP2007/003332 2006-04-19 2007-04-05 1,4:3,6-dianhydromannitol derivatives and use thereof WO2007121883A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102006018912A DE102006018912A1 (en) 2006-04-19 2006-04-19 1,4: 3,6-dianhydromannitol derivatives and their use
DE102006018912.4 2006-04-19

Publications (2)

Publication Number Publication Date
WO2007121883A2 WO2007121883A2 (en) 2007-11-01
WO2007121883A3 true WO2007121883A3 (en) 2007-12-21

Family

ID=38536820

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2007/003332 WO2007121883A2 (en) 2006-04-19 2007-04-05 1,4:3,6-dianhydromannitol derivatives and use thereof

Country Status (2)

Country Link
DE (1) DE102006018912A1 (en)
WO (1) WO2007121883A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI429404B (en) * 2008-03-03 2014-03-11 Senomyx Inc Isosorbide derivatives and their use as flavor modifiers, tastants, and taste enhancers
FR2945536B1 (en) * 2009-05-15 2012-09-28 Roquette Freres MONOMERS DERIVED FROM FUNCTIONALIZED DIANHYDROHEXITOL DERIVATIVES, INTERMEDIATES AND TRIAZOLE POLYMERS / TETRAZOLES FROM CYCLOADDITION, PROCESS FOR THE PREPARATION OF DIFFERENT COMPOUNDS AND APPLICATIONS.
EP2945950B1 (en) 2013-01-17 2017-03-01 Sanofi Isomannide derivatives as inhibitors of soluble epoxide hydrolase

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2399440A1 (en) * 1977-08-02 1979-03-02 Inst Organicheskogo Sinteza Ak 1- (5-FLUORO-URACILYL-1) -2,5-DI-O-ACETYL-B-D-GLUCOFURANURONO-6,3-LACTONE AND ITS APPLICATION IN THERAPEUTICS
EP1038941A1 (en) * 1999-03-25 2000-09-27 Basf Aktiengesellschaft Chiral compounds and their use as chiral dopants for preparing cholesteric liquid crystal compositions

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2399440A1 (en) * 1977-08-02 1979-03-02 Inst Organicheskogo Sinteza Ak 1- (5-FLUORO-URACILYL-1) -2,5-DI-O-ACETYL-B-D-GLUCOFURANURONO-6,3-LACTONE AND ITS APPLICATION IN THERAPEUTICS
EP1038941A1 (en) * 1999-03-25 2000-09-27 Basf Aktiengesellschaft Chiral compounds and their use as chiral dopants for preparing cholesteric liquid crystal compositions

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
SHIGEKI SASAKI ET AL.: "Selective Formation of Stable Triplexes Including a TA or a CG Interrupting Site with New Bicyclic Nucleoside Analogues (WNA)", J.AM.CHEM.SOC., vol. 126, no. 2, 2004, pages 516 - 528, XP002454068 *

Also Published As

Publication number Publication date
WO2007121883A2 (en) 2007-11-01
DE102006018912A1 (en) 2007-10-25

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