WO2007121119A3 - Apparatus and method for detecting gastroesophageal reflux disease (gerd) - Google Patents

Apparatus and method for detecting gastroesophageal reflux disease (gerd) Download PDF

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Publication number
WO2007121119A3
WO2007121119A3 PCT/US2007/066146 US2007066146W WO2007121119A3 WO 2007121119 A3 WO2007121119 A3 WO 2007121119A3 US 2007066146 W US2007066146 W US 2007066146W WO 2007121119 A3 WO2007121119 A3 WO 2007121119A3
Authority
WO
WIPO (PCT)
Prior art keywords
capsule
gerd
esophagus
acid
reflux disease
Prior art date
Application number
PCT/US2007/066146
Other languages
French (fr)
Other versions
WO2007121119A2 (en
Inventor
Richard A Baylor
Original Assignee
Esophamet Corp
Richard A Baylor
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Esophamet Corp, Richard A Baylor filed Critical Esophamet Corp
Priority to CA002648937A priority Critical patent/CA2648937A1/en
Publication of WO2007121119A2 publication Critical patent/WO2007121119A2/en
Publication of WO2007121119A3 publication Critical patent/WO2007121119A3/en
Priority to GB0819456A priority patent/GB2450662A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14539—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring pH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/42—Detecting, measuring or recording for evaluating the gastrointestinal, the endocrine or the exocrine systems
    • A61B5/4211—Diagnosing or evaluating reflux
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/84—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/16—Details of sensor housings or probes; Details of structural supports for sensors
    • A61B2562/162—Capsule shaped sensor housings, e.g. for swallowing or implantation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/06—Gastro-intestinal diseases
    • G01N2800/062—Gastritis or peptic ulcer disease

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Surgery (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

A method and an apparatus are disclosed for detecting gastroesophageal reflux disease (GERD) in the esophagus of a patient. A capsule with pH-sensitive dissolving properties is placed in the lower portion of the esophagus of the patient. The capsule is removed after a period of time, such as about 24 hours. The change in weight or volume of the capsule, or both, allows detection of acid reflux, i.e., the presence of acid in the esophagus for even a relatively short duration during the period of time. If the weight or volume change is significant, the capsule allows diagnosis of GERD. Alternatively, an amount of time during which the capsule was exposed to acid in the esophagus may be determined by dissolving the capsule remaining and using a solution property, such as conductivity, pH, color, or turbidity.
PCT/US2007/066146 2006-04-10 2007-04-06 Apparatus and method for detecting gastroesophageal reflux disease (gerd) WO2007121119A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CA002648937A CA2648937A1 (en) 2006-04-10 2007-04-06 Apparatus and method for detecting gastroesophageal reflux disease (gerd)
GB0819456A GB2450662A (en) 2006-04-10 2008-10-23 Apparatus and method for detecting gastroesophageal reflux disease (gerd)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US79070106P 2006-04-10 2006-04-10
US60/790,701 2006-04-10
US11/459,454 2006-07-24
US11/459,454 US20070238942A1 (en) 2006-04-10 2006-07-24 Apparatus and method for detecting gastroesophageal reflux disease (gerd)

Publications (2)

Publication Number Publication Date
WO2007121119A2 WO2007121119A2 (en) 2007-10-25
WO2007121119A3 true WO2007121119A3 (en) 2008-05-22

Family

ID=38576256

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/066146 WO2007121119A2 (en) 2006-04-10 2007-04-06 Apparatus and method for detecting gastroesophageal reflux disease (gerd)

Country Status (4)

Country Link
US (1) US20070238942A1 (en)
CA (1) CA2648937A1 (en)
GB (1) GB2450662A (en)
WO (1) WO2007121119A2 (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9020597B2 (en) 2008-11-12 2015-04-28 Endostim, Inc. Device and implantation system for electrical stimulation of biological systems
US9345879B2 (en) 2006-10-09 2016-05-24 Endostim, Inc. Device and implantation system for electrical stimulation of biological systems
US9724510B2 (en) 2006-10-09 2017-08-08 Endostim, Inc. System and methods for electrical stimulation of biological systems
US20150224310A1 (en) 2006-10-09 2015-08-13 Endostim, Inc. Device and Implantation System for Electrical Stimulation of Biological Systems
US11577077B2 (en) 2006-10-09 2023-02-14 Endostim, Inc. Systems and methods for electrical stimulation of biological systems
WO2009061819A1 (en) * 2007-11-05 2009-05-14 The Regents Of The University Of Colorado Minimally-invasive measurement of esophageal inflammation
EP2237832B1 (en) 2008-01-25 2017-01-04 Virender K. Sharma Implantable stimulator for treating obesity including an anchoring unit
WO2010042686A1 (en) 2008-10-09 2010-04-15 Sharma Virender K Method and apparatus for stimulating the vascular system
US10603489B2 (en) 2008-10-09 2020-03-31 Virender K. Sharma Methods and apparatuses for stimulating blood vessels in order to control, treat, and/or prevent a hemorrhage
US8447404B2 (en) 2010-03-05 2013-05-21 Endostim, Inc. Device and implantation system for electrical stimulation of biological systems
US11717681B2 (en) 2010-03-05 2023-08-08 Endostim, Inc. Systems and methods for treating gastroesophageal reflux disease
WO2012142539A1 (en) * 2011-04-14 2012-10-18 Endostim, Inc. Systems and methods for treating gastroesophageal reflux disease
US9925367B2 (en) 2011-09-02 2018-03-27 Endostim, Inc. Laparoscopic lead implantation method
US9037245B2 (en) 2011-09-02 2015-05-19 Endostim, Inc. Endoscopic lead implantation method
GB2495479B (en) * 2011-10-03 2015-12-02 Babiesfirst Ltd Reflux probe
US9782583B2 (en) 2012-02-21 2017-10-10 Virender K. Sharma System and method for electrical stimulation of anorectal structures to treat urinary dysfunction
US8706234B2 (en) 2012-02-21 2014-04-22 Virender K. Sharma System and method for electrical stimulation of anorectal structures to treat anal dysfunction
US10576278B2 (en) 2012-02-21 2020-03-03 Virender K. Sharma System and method for electrical stimulation of anorectal structures to treat urinary dysfunction
EP2888000A4 (en) 2012-08-23 2016-07-06 Endostim Inc Device and implantation system for electrical stimulation of biological systems
US9498619B2 (en) 2013-02-26 2016-11-22 Endostim, Inc. Implantable electrical stimulation leads
US9827425B2 (en) 2013-09-03 2017-11-28 Endostim, Inc. Methods and systems of electrode polarity switching in electrical stimulation therapy
EP3220999A2 (en) 2014-11-17 2017-09-27 Endostim, Inc. Implantable electro-medical device programmable for improved operational life
EP3500178A1 (en) * 2016-08-18 2019-06-26 Mitchell Lawrence Jones Sampling systems and related materials and methods
WO2018094207A1 (en) 2016-11-17 2018-05-24 Endostim, Inc. Modular stimulation system for the treatment of gastrointestinal disorders
US12053626B2 (en) 2017-04-06 2024-08-06 Endostim, Inc. Surface electrodes
US11786142B2 (en) * 2019-01-11 2023-10-17 Tokitae Llc Ingestible RFID tag and reader system
CN111067492A (en) * 2020-01-15 2020-04-28 河北医科大学第二医院 Gastroesophageal gas reflux detection device

Citations (4)

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Publication number Priority date Publication date Assignee Title
EP0247634A2 (en) * 1986-05-30 1987-12-02 Warner-Lambert Company Coated dosage forms
EP0410422A2 (en) * 1989-07-25 1991-01-30 Otsuka Pharmaceutical Co., Ltd. A highly absorbable pharmaceutical composition
US6475145B1 (en) * 2000-05-17 2002-11-05 Baymar, Inc. Method and apparatus for detection of acid reflux
WO2003043602A1 (en) * 2001-11-20 2003-05-30 Korea Dds Pharmaceutical Co., Ltd. Solid dispersions containing substituted cyclodextrin and insoluble drug and their preparations

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US4632119A (en) * 1985-10-23 1986-12-30 University Of Health Sciences/The Chicago Medical School Ambulatory esophageal pH monitor
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Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0247634A2 (en) * 1986-05-30 1987-12-02 Warner-Lambert Company Coated dosage forms
EP0410422A2 (en) * 1989-07-25 1991-01-30 Otsuka Pharmaceutical Co., Ltd. A highly absorbable pharmaceutical composition
US6475145B1 (en) * 2000-05-17 2002-11-05 Baymar, Inc. Method and apparatus for detection of acid reflux
WO2003043602A1 (en) * 2001-11-20 2003-05-30 Korea Dds Pharmaceutical Co., Ltd. Solid dispersions containing substituted cyclodextrin and insoluble drug and their preparations

Also Published As

Publication number Publication date
GB0819456D0 (en) 2008-12-03
GB2450662A (en) 2008-12-31
WO2007121119A2 (en) 2007-10-25
CA2648937A1 (en) 2007-10-25
US20070238942A1 (en) 2007-10-11

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