WO2007109299A3 - Peptide - Google Patents

Peptide Download PDF

Info

Publication number
WO2007109299A3
WO2007109299A3 PCT/US2007/006979 US2007006979W WO2007109299A3 WO 2007109299 A3 WO2007109299 A3 WO 2007109299A3 US 2007006979 W US2007006979 W US 2007006979W WO 2007109299 A3 WO2007109299 A3 WO 2007109299A3
Authority
WO
WIPO (PCT)
Prior art keywords
estrogen receptor
peptide
pure
degraders
antiestrogens
Prior art date
Application number
PCT/US2007/006979
Other languages
French (fr)
Other versions
WO2007109299A2 (en
Inventor
Donald P Mcdonnell
Bryan M Wittmann
Original Assignee
Univ Duke
Donald P Mcdonnell
Bryan M Wittmann
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Duke, Donald P Mcdonnell, Bryan M Wittmann filed Critical Univ Duke
Publication of WO2007109299A2 publication Critical patent/WO2007109299A2/en
Publication of WO2007109299A3 publication Critical patent/WO2007109299A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/743—Steroid hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids

Abstract

The present invention relates in general to pure antiestrogens and selective estrogen receptor degraders and, in particular, to a peptide that interacts specifically with pure anti estrogen bound to estrogen receptor α (ERα) and to a method of identifying pure antiestrogens or selective estrogen receptor degraders using same.
PCT/US2007/006979 2006-03-21 2007-03-21 Peptide WO2007109299A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78386006P 2006-03-21 2006-03-21
US60/783,860 2006-03-21

Publications (2)

Publication Number Publication Date
WO2007109299A2 WO2007109299A2 (en) 2007-09-27
WO2007109299A3 true WO2007109299A3 (en) 2008-06-26

Family

ID=38523071

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/006979 WO2007109299A2 (en) 2006-03-21 2007-03-21 Peptide

Country Status (1)

Country Link
WO (1) WO2007109299A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5955259A (en) * 1996-12-19 1999-09-21 Brandeis University Method for assessing modulation of potassium ion channel activity
US20020098524A1 (en) * 2000-04-14 2002-07-25 Murray Christopher J. Methods for selective targeting

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5955259A (en) * 1996-12-19 1999-09-21 Brandeis University Method for assessing modulation of potassium ion channel activity
US20020098524A1 (en) * 2000-04-14 2002-07-25 Murray Christopher J. Methods for selective targeting

Also Published As

Publication number Publication date
WO2007109299A2 (en) 2007-09-27

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