WO2007107835A3 - Stable liquid formulations of antiepileptic agents - Google Patents

Stable liquid formulations of antiepileptic agents Download PDF

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Publication number
WO2007107835A3
WO2007107835A3 PCT/IB2007/000652 IB2007000652W WO2007107835A3 WO 2007107835 A3 WO2007107835 A3 WO 2007107835A3 IB 2007000652 W IB2007000652 W IB 2007000652W WO 2007107835 A3 WO2007107835 A3 WO 2007107835A3
Authority
WO
WIPO (PCT)
Prior art keywords
liquid formulations
stable liquid
antiepileptic agents
polyhydric alcohol
stable
Prior art date
Application number
PCT/IB2007/000652
Other languages
French (fr)
Other versions
WO2007107835A2 (en
Inventor
Vikas Yande
Shailesh Kulkarni
Srichakravar Narasimharaghavan
Sivakumaran Meenakshisunderam
Original Assignee
Aurobindo Pharma Ltd
Vikas Yande
Shailesh Kulkarni
Srichakravar Narasimharaghavan
Sivakumaran Meenakshisunderam
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aurobindo Pharma Ltd, Vikas Yande, Shailesh Kulkarni, Srichakravar Narasimharaghavan, Sivakumaran Meenakshisunderam filed Critical Aurobindo Pharma Ltd
Publication of WO2007107835A2 publication Critical patent/WO2007107835A2/en
Publication of WO2007107835A3 publication Critical patent/WO2007107835A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

The present invention relates to a stable and taste masked oral liquid formulation comprising GABA analogues and a polyhydric alcohol containing 2 to 6 carbon atoms, wherein the content of polyhydric alcohol is equal to or less than 20% weight/volume (w/v) of the composition.
PCT/IB2007/000652 2006-03-17 2007-03-14 Stable liquid formulations of antiepileptic agents WO2007107835A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN489/CHE/2006 2006-03-17
IN489CH2006 2006-03-17

Publications (2)

Publication Number Publication Date
WO2007107835A2 WO2007107835A2 (en) 2007-09-27
WO2007107835A3 true WO2007107835A3 (en) 2008-04-17

Family

ID=38462761

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2007/000652 WO2007107835A2 (en) 2006-03-17 2007-03-14 Stable liquid formulations of antiepileptic agents

Country Status (1)

Country Link
WO (1) WO2007107835A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU230031B1 (en) * 2010-03-01 2015-05-28 Egis Gyógyszergyár Nyilvánosan Működő Részvénytársaság Stabilized pharmaceutical composition containing pregabalin and isomalt
WO2015144825A1 (en) * 2014-03-27 2015-10-01 Sanovel Ilac Sanayi Ve Ticaret A.S. Oral liquid pharmaceutical solution of gabapentin
CN112107537A (en) * 2019-06-19 2020-12-22 北京万全德众医药生物技术有限公司 Pregabalin oral solution and preparation method thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0458751A1 (en) * 1990-05-25 1991-11-27 Warner-Lambert Company Delivery system for cyclic amino acids with improved taste, texture and compressibility
WO1999059573A1 (en) * 1998-05-15 1999-11-25 Warner-Lambert Company Stabilized pharmaceutical preparations of gamma-aminobutyric acid derivatives and process for preparing the same
WO2004093867A2 (en) * 2003-03-25 2004-11-04 Kiel Laboratories, Inc. Phenolic acid salts of gabapentin in liquid and/or semi-solid dosage forms and methods of use
WO2006008640A1 (en) * 2004-07-15 2006-01-26 Pharmacia & Upjohn Company Llc Non-aqueous suspension containing a drug having an unpleasant taste

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0458751A1 (en) * 1990-05-25 1991-11-27 Warner-Lambert Company Delivery system for cyclic amino acids with improved taste, texture and compressibility
WO1999059573A1 (en) * 1998-05-15 1999-11-25 Warner-Lambert Company Stabilized pharmaceutical preparations of gamma-aminobutyric acid derivatives and process for preparing the same
WO2004093867A2 (en) * 2003-03-25 2004-11-04 Kiel Laboratories, Inc. Phenolic acid salts of gabapentin in liquid and/or semi-solid dosage forms and methods of use
WO2006008640A1 (en) * 2004-07-15 2006-01-26 Pharmacia & Upjohn Company Llc Non-aqueous suspension containing a drug having an unpleasant taste

Also Published As

Publication number Publication date
WO2007107835A2 (en) 2007-09-27

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