WO2007096726A3 - Process for the preparation of a glucose derivative - Google Patents

Process for the preparation of a glucose derivative Download PDF

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Publication number
WO2007096726A3
WO2007096726A3 PCT/IB2007/000332 IB2007000332W WO2007096726A3 WO 2007096726 A3 WO2007096726 A3 WO 2007096726A3 IB 2007000332 W IB2007000332 W IB 2007000332W WO 2007096726 A3 WO2007096726 A3 WO 2007096726A3
Authority
WO
WIPO (PCT)
Prior art keywords
preparation
glucose derivative
penta
acetyl sucrose
trispa
Prior art date
Application number
PCT/IB2007/000332
Other languages
French (fr)
Other versions
WO2007096726A2 (en
Inventor
Milind Moreshwar Gharpure
Baburao Manikrao Bhawal
Umesh Rewaji Zope
Sanjay Shankar Deshmukh
Swapnil Panditrao Sonawane
Satish Ramnalal Mehta
Original Assignee
Emcure Pharmaceuticals Ltd
Milind Moreshwar Gharpure
Baburao Manikrao Bhawal
Umesh Rewaji Zope
Sanjay Shankar Deshmukh
Swapnil Panditrao Sonawane
Satish Ramnalal Mehta
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Emcure Pharmaceuticals Ltd, Milind Moreshwar Gharpure, Baburao Manikrao Bhawal, Umesh Rewaji Zope, Sanjay Shankar Deshmukh, Swapnil Panditrao Sonawane, Satish Ramnalal Mehta filed Critical Emcure Pharmaceuticals Ltd
Publication of WO2007096726A2 publication Critical patent/WO2007096726A2/en
Publication of WO2007096726A3 publication Critical patent/WO2007096726A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/02—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to halogen

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)

Abstract

The present invention relates to an improved, safe, commercially viable, cost effective and eco friendly process for the preparation of 4,1',6'-trichloro-4,1',6'-trideoxygalactosucrose (Sucralose). The invention is directed towards the convenient synthesis of 2,3,4,3',4'-penta-O-acetyl sucrose (4-PAS) from 6,1',6'-tri-O-trityl-penta-O-acetyl sucrose ('TRISPA').
PCT/IB2007/000332 2006-02-20 2007-02-13 Process for the preparation of a glucose derivative WO2007096726A2 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
IN237MU2006 2006-02-20
IN237/MUM/2006 2006-02-20
IN649/MUM/2006 2006-04-26
IN649MU2006 2006-04-26
IN887MU2006 2006-06-08
IN887/MUM/2006 2006-06-08

Publications (2)

Publication Number Publication Date
WO2007096726A2 WO2007096726A2 (en) 2007-08-30
WO2007096726A3 true WO2007096726A3 (en) 2007-11-22

Family

ID=38175816

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2007/000332 WO2007096726A2 (en) 2006-02-20 2007-02-13 Process for the preparation of a glucose derivative

Country Status (1)

Country Link
WO (1) WO2007096726A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009087676A1 (en) * 2007-12-24 2009-07-16 Alembic Limited An improved process for the preparation of 2, 3, 6, 3 ', 4 ' - penta- o -acetylsucrose
WO2010013157A2 (en) * 2008-07-29 2010-02-04 Alembic Limited Cost efficient process for preparation of sucralose
CN106632533A (en) * 2016-12-09 2017-05-10 福建科宏生物工程股份有限公司 Low-temperature and efficient preparation method of sucrose-6-acetate
CN111808152B (en) * 2020-06-02 2021-10-08 山东新和成精化科技有限公司 Deacylation method of sucralose-6-acetate

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4362869A (en) * 1907-12-02 1982-12-07 Talres Development (N.A.) N.V. Process for the preparation of 4,1',6'-trichloro-4,1',6'-trideoxygalactosucrose
US4801700A (en) * 1985-10-21 1989-01-31 Mcneilab, Inc. Process for the preparation of 1,6-dichloro-1,6-dideoxy-β-D-fructofuranosyl-4-chloro-4-deoxy-α-

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4362869A (en) * 1907-12-02 1982-12-07 Talres Development (N.A.) N.V. Process for the preparation of 4,1',6'-trichloro-4,1',6'-trideoxygalactosucrose
US4801700A (en) * 1985-10-21 1989-01-31 Mcneilab, Inc. Process for the preparation of 1,6-dichloro-1,6-dideoxy-β-D-fructofuranosyl-4-chloro-4-deoxy-α-

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MILLER G A: "SUCRALOSE", TRENDS IN FOOD SCIENCE AND TECHNOLOGY, ELSEVIER SCIENCE PUBLISHERS, GB, 1991, pages 173 - 195, XP001105020, ISSN: 0924-2244 *

Also Published As

Publication number Publication date
WO2007096726A2 (en) 2007-08-30

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