WO2007095634A3 - Prion protein detection - Google Patents

Prion protein detection Download PDF

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Publication number
WO2007095634A3
WO2007095634A3 PCT/US2007/062337 US2007062337W WO2007095634A3 WO 2007095634 A3 WO2007095634 A3 WO 2007095634A3 US 2007062337 W US2007062337 W US 2007062337W WO 2007095634 A3 WO2007095634 A3 WO 2007095634A3
Authority
WO
WIPO (PCT)
Prior art keywords
prion protein
protein detection
antibodies
exposed region
optically exposed
Prior art date
Application number
PCT/US2007/062337
Other languages
French (fr)
Other versions
WO2007095634A8 (en
WO2007095634A2 (en
Inventor
Maureen Angela Dyer
William Paynter Hanson
Thrygve Richard Meeker
Original Assignee
Hanson Technologies Inc
Maureen Angela Dyer
William Paynter Hanson
Thrygve Richard Meeker
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hanson Technologies Inc, Maureen Angela Dyer, William Paynter Hanson, Thrygve Richard Meeker filed Critical Hanson Technologies Inc
Publication of WO2007095634A2 publication Critical patent/WO2007095634A2/en
Publication of WO2007095634A3 publication Critical patent/WO2007095634A3/en
Publication of WO2007095634A8 publication Critical patent/WO2007095634A8/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

A waveguide device comprises a multimode waveguide having a surface-bearing patterned reflective coating defining a reflectively coated region and an optically exposed region on the surface, wherein one or more first antibodies are covalently bonded to or non-covalently immobilized on the optically exposed region, and wherein the one or more first antibodies selectively binds a prion protein. Use of said device to detect prions.
PCT/US2007/062337 2006-02-17 2007-02-16 Prion protein detection WO2007095634A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US77434806P 2006-02-17 2006-02-17
US60/774,348 2006-02-17
US77962006P 2006-03-06 2006-03-06
US60/779,620 2006-03-06

Publications (3)

Publication Number Publication Date
WO2007095634A2 WO2007095634A2 (en) 2007-08-23
WO2007095634A3 true WO2007095634A3 (en) 2008-04-03
WO2007095634A8 WO2007095634A8 (en) 2009-07-30

Family

ID=38372265

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/062337 WO2007095634A2 (en) 2006-02-17 2007-02-16 Prion protein detection

Country Status (1)

Country Link
WO (1) WO2007095634A2 (en)

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0886141A1 (en) * 1997-06-23 1998-12-23 C.S.E.M. Centre Suisse D'electronique Et De Microtechnique Sa Optical sensor unit and procedure for the ultrasensitive detection of chemical or biochemical analytes
EP0887645A1 (en) * 1997-06-23 1998-12-30 C.S.E.M. Centre Suisse D'electronique Et De Microtechnique Sa Procedure and instrumentation for the ultrasensitive detection of prions, prion binding biomolecules and other biomolecules
WO2000062105A1 (en) * 1999-04-09 2000-10-19 The Government Of The United States Of America As Represented By The Secretary Of The Navy Reflectively coated optical waveguide and fluidics cell integration
US6346376B1 (en) * 1998-06-03 2002-02-12 Centre Suisse D'electronique Et De Mictotechnique Sa Optical sensor unit and procedure for the ultrasensitive detection of chemical or biochemical analytes
US20020031836A1 (en) * 2000-09-11 2002-03-14 Feldstein Mark J. Fluidics system
WO2003031562A1 (en) * 2001-10-10 2003-04-17 Pritest, Inc. Portable biosensor apparatus with controlled flow
US20040018554A1 (en) * 2001-05-15 2004-01-29 Green Larry R. Methods and compositions for detection of bovine spongiform encephalopathy and variant creutzfeldt-jacob disease
WO2004076678A2 (en) * 2003-02-24 2004-09-10 Pritest, Inc. Translucent solid matrix assay device for microarray analysis
WO2006063437A1 (en) * 2004-12-15 2006-06-22 University Of Guelph Prion sensors for diagnosis of transmissible spongiform encephalopathy or for detection of prions, and use thereof

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0886141A1 (en) * 1997-06-23 1998-12-23 C.S.E.M. Centre Suisse D'electronique Et De Microtechnique Sa Optical sensor unit and procedure for the ultrasensitive detection of chemical or biochemical analytes
EP0887645A1 (en) * 1997-06-23 1998-12-30 C.S.E.M. Centre Suisse D'electronique Et De Microtechnique Sa Procedure and instrumentation for the ultrasensitive detection of prions, prion binding biomolecules and other biomolecules
US6346376B1 (en) * 1998-06-03 2002-02-12 Centre Suisse D'electronique Et De Mictotechnique Sa Optical sensor unit and procedure for the ultrasensitive detection of chemical or biochemical analytes
WO2000062105A1 (en) * 1999-04-09 2000-10-19 The Government Of The United States Of America As Represented By The Secretary Of The Navy Reflectively coated optical waveguide and fluidics cell integration
US20020031836A1 (en) * 2000-09-11 2002-03-14 Feldstein Mark J. Fluidics system
US20040018554A1 (en) * 2001-05-15 2004-01-29 Green Larry R. Methods and compositions for detection of bovine spongiform encephalopathy and variant creutzfeldt-jacob disease
WO2003031562A1 (en) * 2001-10-10 2003-04-17 Pritest, Inc. Portable biosensor apparatus with controlled flow
WO2004076678A2 (en) * 2003-02-24 2004-09-10 Pritest, Inc. Translucent solid matrix assay device for microarray analysis
US20060211044A1 (en) * 2003-02-24 2006-09-21 Green Lawrence R Translucent solid matrix assay device dor microarray analysis
WO2006063437A1 (en) * 2004-12-15 2006-06-22 University Of Guelph Prion sensors for diagnosis of transmissible spongiform encephalopathy or for detection of prions, and use thereof

Also Published As

Publication number Publication date
WO2007095634A8 (en) 2009-07-30
WO2007095634A2 (en) 2007-08-23

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