WO2007092607A3 - Traitement d'infections virales hémorragiques au moyen d'un inhibiteur du facteur tissulaire - Google Patents

Traitement d'infections virales hémorragiques au moyen d'un inhibiteur du facteur tissulaire Download PDF

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Publication number
WO2007092607A3
WO2007092607A3 PCT/US2007/003528 US2007003528W WO2007092607A3 WO 2007092607 A3 WO2007092607 A3 WO 2007092607A3 US 2007003528 W US2007003528 W US 2007003528W WO 2007092607 A3 WO2007092607 A3 WO 2007092607A3
Authority
WO
WIPO (PCT)
Prior art keywords
treatment
viral infections
tissue factor
factor inhibitor
hemorrhagic viral
Prior art date
Application number
PCT/US2007/003528
Other languages
English (en)
Other versions
WO2007092607A2 (fr
Inventor
Sek Chung Michael Fung
Original Assignee
Genentech Inc
Sek Chung Michael Fung
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc, Sek Chung Michael Fung filed Critical Genentech Inc
Publication of WO2007092607A2 publication Critical patent/WO2007092607A2/fr
Publication of WO2007092607A3 publication Critical patent/WO2007092607A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention concerne de nouveaux procédés pour traiter des infections virales hémorragiques, par exemple des infections par le virus Ebola ou Marburg, par administration d'un inhibiteur du facteur tissulaire.
PCT/US2007/003528 2006-02-09 2007-02-08 Traitement d'infections virales hémorragiques au moyen d'un inhibiteur du facteur tissulaire WO2007092607A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US76676106P 2006-02-09 2006-02-09
US60/766,761 2006-02-09

Publications (2)

Publication Number Publication Date
WO2007092607A2 WO2007092607A2 (fr) 2007-08-16
WO2007092607A3 true WO2007092607A3 (fr) 2008-07-24

Family

ID=38345831

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/003528 WO2007092607A2 (fr) 2006-02-09 2007-02-08 Traitement d'infections virales hémorragiques au moyen d'un inhibiteur du facteur tissulaire

Country Status (1)

Country Link
WO (1) WO2007092607A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20180072815A1 (en) * 2014-10-23 2018-03-15 Singh Biotechnology, Llc Single Domain Antibodies Directed Against Intracellular Antigens
CA3184987A1 (fr) * 2020-07-10 2022-01-13 Thi-Sau Migone Traitement de maladies inflammatoires faisant appel a des anticorps anti-facteur tissulaire
US20240108688A1 (en) 2020-11-20 2024-04-04 Universitätsmedizin Der Johannes Gutenberg-Universität Mainz Inhibitors of the tissue factor-protease activated receptor 2 (TF-PAR2) signaling pathway for use in the treatment or prevention of heart failure (HF) and associated or resulting diseases

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0300988A2 (fr) * 1987-07-23 1989-01-25 Washington University Inhibiteur de facteur tissulaire
WO2000018398A1 (fr) * 1998-09-25 2000-04-06 Sunol Molecular Corporation Composes pharmaceutiquement actifs, et methodes d'utilisation correspondantes
WO2001016183A1 (fr) * 1999-08-30 2001-03-08 U.S. Army Medical Research Institute Of Infectious Diseases Anticorps monoclonaux et vaccins contre les epitopes de la glycoproteine du virus d'ebola
US20010028880A1 (en) * 1998-11-20 2001-10-11 Fisher Charles Jack Method of treating viral hemorrhagic fever
US20040266672A1 (en) * 2003-05-06 2004-12-30 Vlasuk George P Method of treatment of hemorrhagic disease using a factor VIIa/tissue factor inhibitor
US20060281701A1 (en) * 2004-11-01 2006-12-14 Stein David A Antisense antiviral compounds and methods for treating a filovirus infection

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0300988A2 (fr) * 1987-07-23 1989-01-25 Washington University Inhibiteur de facteur tissulaire
WO2000018398A1 (fr) * 1998-09-25 2000-04-06 Sunol Molecular Corporation Composes pharmaceutiquement actifs, et methodes d'utilisation correspondantes
US20010028880A1 (en) * 1998-11-20 2001-10-11 Fisher Charles Jack Method of treating viral hemorrhagic fever
WO2001016183A1 (fr) * 1999-08-30 2001-03-08 U.S. Army Medical Research Institute Of Infectious Diseases Anticorps monoclonaux et vaccins contre les epitopes de la glycoproteine du virus d'ebola
US20040266672A1 (en) * 2003-05-06 2004-12-30 Vlasuk George P Method of treatment of hemorrhagic disease using a factor VIIa/tissue factor inhibitor
US20060281701A1 (en) * 2004-11-01 2006-12-14 Stein David A Antisense antiviral compounds and methods for treating a filovirus infection

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DANA ET AL.: "Virus-like particles exhibit potential as a pan-filovirus vaccine for both Ebola and Marburg viral infections", VACCINE, vol. 23, no. 23, 27 April 2005 (2005-04-27), pages 3033 - 3042 *

Also Published As

Publication number Publication date
WO2007092607A2 (fr) 2007-08-16

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