WO2007092436A3 - Composes pour le traitement de troubles inflammatoires, de troubles de demyelinisation et de cancers - Google Patents

Composes pour le traitement de troubles inflammatoires, de troubles de demyelinisation et de cancers Download PDF

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Publication number
WO2007092436A3
WO2007092436A3 PCT/US2007/003135 US2007003135W WO2007092436A3 WO 2007092436 A3 WO2007092436 A3 WO 2007092436A3 US 2007003135 W US2007003135 W US 2007003135W WO 2007092436 A3 WO2007092436 A3 WO 2007092436A3
Authority
WO
WIPO (PCT)
Prior art keywords
disorders
compounds
cancers
treating inflammatory
demyelinating
Prior art date
Application number
PCT/US2007/003135
Other languages
English (en)
Other versions
WO2007092436A2 (fr
Inventor
Alfred M Ajami
Original Assignee
Xanthus Pharmaceuticals Inc
Alfred M Ajami
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xanthus Pharmaceuticals Inc, Alfred M Ajami filed Critical Xanthus Pharmaceuticals Inc
Priority to US11/893,375 priority Critical patent/US20080108641A1/en
Publication of WO2007092436A2 publication Critical patent/WO2007092436A2/fr
Publication of WO2007092436A3 publication Critical patent/WO2007092436A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention concerne des composés de formule (I) et un procédé de traitement de patient souffrant de troubles inflammatoires et/ou de troubles de démyélinisation, y compris l'administration audit patient d'une quantité thérapeutiquement effective d'un composé de formule (I) ou d'un sel dérivé pharmaceutiquement acceptable. Des définitions des variables sont fournies ici.
PCT/US2007/003135 2006-02-08 2007-02-07 Composes pour le traitement de troubles inflammatoires, de troubles de demyelinisation et de cancers WO2007092436A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US11/893,375 US20080108641A1 (en) 2006-02-08 2007-08-15 Compounds for treating inflammatory disorders, demyelinating disdorders and cancers

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US77190906P 2006-02-08 2006-02-08
US60/771,909 2006-02-08
US83515306P 2006-08-02 2006-08-02
US60/835,153 2006-08-02

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US11/893,375 Continuation-In-Part US20080108641A1 (en) 2006-02-08 2007-08-15 Compounds for treating inflammatory disorders, demyelinating disdorders and cancers

Publications (2)

Publication Number Publication Date
WO2007092436A2 WO2007092436A2 (fr) 2007-08-16
WO2007092436A3 true WO2007092436A3 (fr) 2008-12-18

Family

ID=38185678

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/003135 WO2007092436A2 (fr) 2006-02-08 2007-02-07 Composes pour le traitement de troubles inflammatoires, de troubles de demyelinisation et de cancers

Country Status (1)

Country Link
WO (1) WO2007092436A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007143096A2 (fr) * 2006-06-02 2007-12-13 Xanthus Pharmaceuticals, Inc. Composés destinés au traitement du cancer
US20100016300A1 (en) * 2006-08-02 2010-01-21 Ajami Alfred M Imidazoacridine Compounds for Treating FLT3-Mediated Disorders
WO2008016660A2 (fr) * 2006-08-02 2008-02-07 Xanthus Pharmaceuticals, Inc. Composés de traitement de la leucémie
WO2009017795A1 (fr) * 2007-08-02 2009-02-05 Xanthus Pharmaceuticals, Inc. Composés d'indazole pour le traitement de troubles inflammatoires, de troubles démyélinisants et de cancers
US20180289728A1 (en) * 2015-04-27 2018-10-11 The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center Egr1 targeting molecules for the treatment of inflammatory and hyperproliferative conditions

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992015583A1 (fr) * 1991-03-05 1992-09-17 British Technology Group Ltd. Imidazoacridines et leur utilisation en tant qu'antineoplasique
WO1997038999A1 (fr) * 1996-04-12 1997-10-23 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Composes derives de l'acridone utiles en tant qu'agents antineoplasiques et antiretroviraux
US6229015B1 (en) * 1996-10-07 2001-05-08 Btg International Limited Acridone derivatives and method of preparation of 8-hydroxy imidazoacridinone derivatives
WO2001066545A2 (fr) * 2000-03-07 2001-09-13 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services 1,8-NAPHTHALIMIDE IMIDAZO[4,5,1-de]ACRIDONES POSSEDANT UNE ACTIVITE ANTITUMORALE
WO2006081431A2 (fr) * 2005-01-28 2006-08-03 Xanthus Pharmaceuticals, Inc. Composes utiles dans le traitement des maladies auto-immunes et des troubles de demyelinisation

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992015583A1 (fr) * 1991-03-05 1992-09-17 British Technology Group Ltd. Imidazoacridines et leur utilisation en tant qu'antineoplasique
WO1997038999A1 (fr) * 1996-04-12 1997-10-23 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Composes derives de l'acridone utiles en tant qu'agents antineoplasiques et antiretroviraux
US6229015B1 (en) * 1996-10-07 2001-05-08 Btg International Limited Acridone derivatives and method of preparation of 8-hydroxy imidazoacridinone derivatives
WO2001066545A2 (fr) * 2000-03-07 2001-09-13 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services 1,8-NAPHTHALIMIDE IMIDAZO[4,5,1-de]ACRIDONES POSSEDANT UNE ACTIVITE ANTITUMORALE
WO2006081431A2 (fr) * 2005-01-28 2006-08-03 Xanthus Pharmaceuticals, Inc. Composes utiles dans le traitement des maladies auto-immunes et des troubles de demyelinisation

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MAZERSKA ZOFIA ET AL: "C-1311: Atineoplastic", DRUGS OF THE FUTURE, BARCELONA, ES, vol. 23, no. 7, 1 July 1998 (1998-07-01), pages 702 - 706, XP002459524, ISSN: 0377-8282 *

Also Published As

Publication number Publication date
WO2007092436A2 (fr) 2007-08-16

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