WO2007091991A2 - Suivi automatique de grille de cohérence et de mise au point de faisceaux simultanés pour la tomographie par cohérence optique en temps réel - Google Patents

Suivi automatique de grille de cohérence et de mise au point de faisceaux simultanés pour la tomographie par cohérence optique en temps réel Download PDF

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Publication number
WO2007091991A2
WO2007091991A2 PCT/US2006/001097 US2006001097W WO2007091991A2 WO 2007091991 A2 WO2007091991 A2 WO 2007091991A2 US 2006001097 W US2006001097 W US 2006001097W WO 2007091991 A2 WO2007091991 A2 WO 2007091991A2
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WO
WIPO (PCT)
Prior art keywords
sample
scanning
oct
oct probe
path length
Prior art date
Application number
PCT/US2006/001097
Other languages
English (en)
Other versions
WO2007091991A3 (fr
Inventor
Xingde Li
Original Assignee
University Of Washington
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University Of Washington filed Critical University Of Washington
Publication of WO2007091991A2 publication Critical patent/WO2007091991A2/fr
Publication of WO2007091991A3 publication Critical patent/WO2007091991A3/fr

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B9/00—Measuring instruments characterised by the use of optical techniques
    • G01B9/02—Interferometers
    • G01B9/02055—Reduction or prevention of errors; Testing; Calibration
    • G01B9/02062—Active error reduction, i.e. varying with time
    • G01B9/02063—Active error reduction, i.e. varying with time by particular alignment of focus position, e.g. dynamic focussing in optical coherence tomography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062—Arrangements for scanning
    • A61B5/0066—Optical coherence imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/6852—Catheters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B9/00—Measuring instruments characterised by the use of optical techniques
    • G01B9/02—Interferometers
    • G01B9/02001—Interferometers characterised by controlling or generating intrinsic radiation properties
    • G01B9/02002—Interferometers characterised by controlling or generating intrinsic radiation properties using two or more frequencies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B9/00—Measuring instruments characterised by the use of optical techniques
    • G01B9/02—Interferometers
    • G01B9/02049—Interferometers characterised by particular mechanical design details
    • G01B9/0205—Interferometers characterised by particular mechanical design details of probe head
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B9/00—Measuring instruments characterised by the use of optical techniques
    • G01B9/02—Interferometers
    • G01B9/0209—Low-coherence interferometers
    • G01B9/02091—Tomographic interferometers, e.g. based on optical coherence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/4795—Scattering, i.e. diffuse reflection spatially resolved investigating of object in scattering medium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062—Arrangements for scanning
    • A61B5/0068—Confocal scanning
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B2290/00—Aspects of interferometers not specifically covered by any group under G01B9/02
    • G01B2290/65—Spatial scanning object beam

Definitions

  • FIGURE 4 is high-level flowchart illustrating exemplary steps for carrying out the technique disclosed herein.
  • an OCT probe is positioned adjacent to a sample.
  • geometric focus tracking is implemented during lateral priority scanning.
  • geometric focus tracking involves changing the position of the focal point of the OCT probe in the sample during scanning, which changes the OPL in the sample arm.
  • coherence gate tracking is simultaneously implemented.
  • coherence gate tracking involves determining the change in the OPL of the sample arm due to the geometric focus tracking, and calculating the change in the OPL in the reference arm that is required to maintain an equal OPL in both the sample arm and the reference arm.

Landscapes

  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Optics & Photonics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

La présente invention concerne un procédé et un appareil pour le suivi automatique de mise au point dynamique lors de la tomographie par cohérence optique (OCT) en temps réel par la mise en oeuvre simultanée de suivi de mise au point géométrique (GFT) et de suivi de grille de cohérence (CGT). Le suivi de mise au point géométrique comprend la modification d'une position du foyer de la sonde de tomographie par cohérence optique dans l'échantillon lors du balayage. De préférence, le foyer est déplacé par rapport à l'échantillon sans interruption du profil de faisceau gaussien du scanner. Le suivi de grille de cohérence comprend la détermination d'une modification dans la longueur du chemin optique du bras de l'échantillon due au suivi de mise au point géométrique, et le calcul de la modification dans la longueur du chemin optique dans le bras de référence nécessaire au maintien d'une longueur de chemin optique équivalente tant dans le bras d'échantillon que dans le bras de référence. Le bras de référence est ensuite déplacé en translation par la quantité requise, afin de maximiser le signal de la tomographie par cohérence optique. Une technique de balayage prioritaire latéral est utilisée, et cette technique peut être mise en oeuvre au moyen d'une fibre optique unique appropriée pour une utilisation en endoscopie.
PCT/US2006/001097 2005-01-14 2006-01-13 Suivi automatique de grille de cohérence et de mise au point de faisceaux simultanés pour la tomographie par cohérence optique en temps réel WO2007091991A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64433505P 2005-01-14 2005-01-14
US60/644,335 2005-01-14

Publications (2)

Publication Number Publication Date
WO2007091991A2 true WO2007091991A2 (fr) 2007-08-16
WO2007091991A3 WO2007091991A3 (fr) 2007-11-01

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/001097 WO2007091991A2 (fr) 2005-01-14 2006-01-13 Suivi automatique de grille de cohérence et de mise au point de faisceaux simultanés pour la tomographie par cohérence optique en temps réel

Country Status (1)

Country Link
WO (1) WO2007091991A2 (fr)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8218927B2 (en) 2010-04-19 2012-07-10 National Research Council Of Canada Optical catheter with rotary optical cap
DE102011016852A1 (de) * 2011-04-06 2012-10-11 Laser- Und Medizin-Technologie Gmbh, Berlin Seitlich gerichtet abstrahlende sowie konfokal detektierende Faseroptiken
CN103799975A (zh) * 2014-02-26 2014-05-21 中国科学院光电技术研究所 采用相干门波前传感器的自适应光学oct视网膜成像仪
US9192295B1 (en) 2014-06-11 2015-11-24 L&R Medical Inc. Focusing algorithm in OCT-only systems
EP3021071A1 (fr) * 2014-11-12 2016-05-18 Haag-Streit Ag Procédé de mesure
US9677869B2 (en) 2012-12-05 2017-06-13 Perimeter Medical Imaging, Inc. System and method for generating a wide-field OCT image of a portion of a sample
US10577573B2 (en) 2017-07-18 2020-03-03 Perimeter Medical Imaging, Inc. Sample container for stabilizing and aligning excised biological tissue samples for ex vivo analysis

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5459570A (en) * 1991-04-29 1995-10-17 Massachusetts Institute Of Technology Method and apparatus for performing optical measurements
US20040181148A1 (en) * 2001-10-31 2004-09-16 Olympus Corporation Optical scanning observation apparatus
US20050105096A1 (en) * 2001-02-17 2005-05-19 Fee Michale S. Acousto-optic monitoring and imaging in a depth sensitive manner

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5459570A (en) * 1991-04-29 1995-10-17 Massachusetts Institute Of Technology Method and apparatus for performing optical measurements
US20050105096A1 (en) * 2001-02-17 2005-05-19 Fee Michale S. Acousto-optic monitoring and imaging in a depth sensitive manner
US20040181148A1 (en) * 2001-10-31 2004-09-16 Olympus Corporation Optical scanning observation apparatus

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8218927B2 (en) 2010-04-19 2012-07-10 National Research Council Of Canada Optical catheter with rotary optical cap
DE102011016852A1 (de) * 2011-04-06 2012-10-11 Laser- Und Medizin-Technologie Gmbh, Berlin Seitlich gerichtet abstrahlende sowie konfokal detektierende Faseroptiken
US9677869B2 (en) 2012-12-05 2017-06-13 Perimeter Medical Imaging, Inc. System and method for generating a wide-field OCT image of a portion of a sample
US10359271B2 (en) 2012-12-05 2019-07-23 Perimeter Medical Imaging, Inc. System and method for tissue differentiation in imaging
CN103799975A (zh) * 2014-02-26 2014-05-21 中国科学院光电技术研究所 采用相干门波前传感器的自适应光学oct视网膜成像仪
US9192295B1 (en) 2014-06-11 2015-11-24 L&R Medical Inc. Focusing algorithm in OCT-only systems
EP3154408A4 (fr) * 2014-06-11 2018-02-28 Cellview Imaging Inc. Algorithme de focalisation dans des systèmes uniquement oct
EP3021071A1 (fr) * 2014-11-12 2016-05-18 Haag-Streit Ag Procédé de mesure
US10595723B2 (en) 2014-11-12 2020-03-24 Haag-Streit Ag Measuring method
US10577573B2 (en) 2017-07-18 2020-03-03 Perimeter Medical Imaging, Inc. Sample container for stabilizing and aligning excised biological tissue samples for ex vivo analysis
US10894939B2 (en) 2017-07-18 2021-01-19 Perimeter Medical Imaging, Inc. Sample container for stabilizing and aligning excised biological tissue samples for ex vivo analysis

Also Published As

Publication number Publication date
WO2007091991A3 (fr) 2007-11-01

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