WO2007090433A8 - Purified oxides with novel morphologies formed from ti-alloys - Google Patents

Purified oxides with novel morphologies formed from ti-alloys

Info

Publication number
WO2007090433A8
WO2007090433A8 PCT/EP2006/002239 EP2006002239W WO2007090433A8 WO 2007090433 A8 WO2007090433 A8 WO 2007090433A8 EP 2006002239 W EP2006002239 W EP 2006002239W WO 2007090433 A8 WO2007090433 A8 WO 2007090433A8
Authority
WO
WIPO (PCT)
Prior art keywords
alloys
oxides
spark
porous
mixed
Prior art date
Application number
PCT/EP2006/002239
Other languages
French (fr)
Other versions
WO2007090433A3 (en
WO2007090433A2 (en
Inventor
Philippe Kern
Olivier Zinger
Original Assignee
Plus Orthopedics Ag
Schweizerische Material Pruefu
Philippe Kern
Olivier Zinger
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Plus Orthopedics Ag, Schweizerische Material Pruefu, Philippe Kern, Olivier Zinger filed Critical Plus Orthopedics Ag
Publication of WO2007090433A2 publication Critical patent/WO2007090433A2/en
Publication of WO2007090433A8 publication Critical patent/WO2007090433A8/en
Publication of WO2007090433A3 publication Critical patent/WO2007090433A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/04—Metals or alloys
    • A61L27/06—Titanium or titanium alloys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/30—Inorganic materials
    • A61L27/306—Other specific inorganic materials not covered by A61L27/303 - A61L27/32
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • C—CHEMISTRY; METALLURGY
    • C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
    • C22C—ALLOYS
    • C22C14/00—Alloys based on titanium
    • C—CHEMISTRY; METALLURGY
    • C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
    • C23F—NON-MECHANICAL REMOVAL OF METALLIC MATERIAL FROM SURFACE; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL; MULTI-STEP PROCESSES FOR SURFACE TREATMENT OF METALLIC MATERIAL INVOLVING AT LEAST ONE PROCESS PROVIDED FOR IN CLASS C23 AND AT LEAST ONE PROCESS COVERED BY SUBCLASS C21D OR C22F OR CLASS C25
    • C23F1/00—Etching metallic material by chemical means
    • C23F1/10—Etching compositions
    • C23F1/14—Aqueous compositions
    • C23F1/16—Acidic compositions
    • C23F1/26—Acidic compositions for etching refractory metals
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25D—PROCESSES FOR THE ELECTROLYTIC OR ELECTROPHORETIC PRODUCTION OF COATINGS; ELECTROFORMING; APPARATUS THEREFOR
    • C25D11/00—Electrolytic coating by surface reaction, i.e. forming conversion layers
    • C25D11/02—Anodisation
    • C25D11/024—Anodisation under pulsed or modulated current or potential
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25D—PROCESSES FOR THE ELECTROLYTIC OR ELECTROPHORETIC PRODUCTION OF COATINGS; ELECTROFORMING; APPARATUS THEREFOR
    • C25D11/00—Electrolytic coating by surface reaction, i.e. forming conversion layers
    • C25D11/02—Anodisation
    • C25D11/026—Anodisation with spark discharge
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25D—PROCESSES FOR THE ELECTROLYTIC OR ELECTROPHORETIC PRODUCTION OF COATINGS; ELECTROFORMING; APPARATUS THEREFOR
    • C25D11/00—Electrolytic coating by surface reaction, i.e. forming conversion layers
    • C25D11/02—Anodisation
    • C25D11/26—Anodisation of refractory metals or alloys based thereon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • A61F2002/3082—Grooves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00011—Metals or alloys
    • A61F2310/00023—Titanium or titanium-based alloys, e.g. Ti-Ni alloys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00389—The prosthesis being coated or covered with a particular material
    • A61F2310/00592—Coating or prosthesis-covering structure made of ceramics or of ceramic-like compounds
    • A61F2310/00598—Coating or prosthesis-covering structure made of compounds based on metal oxides or hydroxides
    • A61F2310/00616—Coating made of titanium oxide or hydroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
    • A61L2300/112—Phosphorus-containing compounds, e.g. phosphates, phosphonates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406—Antibiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A61L2300/414—Growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/43—Hormones, e.g. dexamethasone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25D—PROCESSES FOR THE ELECTROLYTIC OR ELECTROPHORETIC PRODUCTION OF COATINGS; ELECTROFORMING; APPARATUS THEREFOR
    • C25D11/00—Electrolytic coating by surface reaction, i.e. forming conversion layers
    • C25D11/02—Anodisation
    • C25D11/04—Anodisation of aluminium or alloys based thereon
    • C25D11/06—Anodisation of aluminium or alloys based thereon characterised by the electrolytes used
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25D—PROCESSES FOR THE ELECTROLYTIC OR ELECTROPHORETIC PRODUCTION OF COATINGS; ELECTROFORMING; APPARATUS THEREFOR
    • C25D11/00—Electrolytic coating by surface reaction, i.e. forming conversion layers
    • C25D11/02—Anodisation
    • C25D11/04—Anodisation of aluminium or alloys based thereon
    • C25D11/16—Pretreatment, e.g. desmutting

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Transplantation (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Metallurgy (AREA)
  • Epidemiology (AREA)
  • Materials Engineering (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Biomedical Technology (AREA)
  • Inorganic Chemistry (AREA)
  • Mechanical Engineering (AREA)
  • Dispersion Chemistry (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Catalysts (AREA)
  • Materials For Medical Uses (AREA)

Abstract

The behaviour of the α/β Ti6A14V and Ti6A17Nb alloys and of the α, c.p. Ti upon spark anodisation in H2SO4, H3PO4 and mixtures of these acids is presented. Chemical depth profiling reveals purified oxides with respect to the substrate alloying elements. This is particularly pronounced on Ti-alloys spark anodized in H2SO4ZH3PO4 mixtures, with Al decreasing continuously towards the surface, and V and Nb remaining hardly detectable in the outermost 200 nm. In addition, the incorporation of S was significantly reduced in mixed electrolytes, while about 8 at-% P was incorporated. A novel oxide morphology with 'worm-like' features in the μm-range, very different from well-known nano/micro-porous oxides, was found in mixed electrolytes under optimized conditions. A similar but more porous-like structure is formed on c.p. Ti. Raman measurements indicate the presence of mixed anatase, rutile and brookite phases on anodized Ti-alloys. Bond strengths of 34 MPa for worm-like and 40-50 MPa for nano/micro- porous morphologies as well as excellent abrasion behaviour characterized the mechanical properties of the oxides. The compatibility of grit-blasting and etching of surfaces with the spark anodisation process for creating multi-topography surfaces is confirmed.
PCT/EP2006/002239 2006-02-09 2006-03-10 Purified oxides with novel morphologies formed from ti-alloys WO2007090433A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP2006001159 2006-02-09
EPPCT/EP2006/001159 2006-02-09

Publications (3)

Publication Number Publication Date
WO2007090433A2 WO2007090433A2 (en) 2007-08-16
WO2007090433A8 true WO2007090433A8 (en) 2007-09-27
WO2007090433A3 WO2007090433A3 (en) 2007-11-01

Family

ID=38109951

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2006/002239 WO2007090433A2 (en) 2006-02-09 2006-03-10 Purified oxides with novel morphologies formed from ti-alloys

Country Status (1)

Country Link
WO (1) WO2007090433A2 (en)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102008026558B4 (en) 2008-06-03 2010-04-01 Königsee Implantate und Instrumente zur Osteosynthese GmbH Electrochemical immersion process in an aqueous electrolyte to produce a biologically degradable surface layer on bases of titanium or titanium-based alloys
DE102008026557A1 (en) 2008-06-03 2009-12-17 Königsee Implantate und Instrumente zur Osteosynthese GmbH Electrochemically produced, biodegradation-stable, ductile and adherent titanium oxide surface layer on titanium or titanium-based alloys
US20140322292A1 (en) 2010-12-10 2014-10-30 Rutgers, The State University Of New Jersey Insulin-mimetics as therapeutic adjuncts for bone regeneration
CA2820297C (en) * 2010-12-10 2019-06-25 University Of Medicine And Dentistry Of New Jersey Implantable devices coated with insulin-mimetic agent composites and methods thereof
CN102691087A (en) * 2011-03-24 2012-09-26 威高集团有限公司 Surface treatment method for improving bioactivity of medical beta-type titanium alloy surface
US9931348B2 (en) 2011-07-06 2018-04-03 Rutgers, The State University Of New Jersey Vanadium compounds as therapeutic adjuncts for cartilage injury and repair
CN102304746A (en) * 2011-09-26 2012-01-04 佳木斯大学 Polypyrrole calcium phosphate/magnesium oxide bioceramic coating and preparation method thereof
CN102397584B (en) * 2011-11-15 2013-10-09 东南大学 Medical magnesium alloy surface degradable composite protective film layer and preparation method thereof
CN103194781A (en) * 2012-01-05 2013-07-10 中国科学院金属研究所 Bioactivity surface modification method used in degradable magnesium alloy
CN103272286B (en) * 2013-05-24 2014-11-12 华南理工大学 Controllable all-degradable biological material and preparation method thereof
CN103272287B (en) * 2013-05-24 2015-03-11 华南理工大学 Biological medical degradable material and preparation method thereof
CN103386148B (en) * 2013-06-19 2014-11-05 江苏科技大学 Bone repair material containing multi-element biocover and preparation method thereof
CN103451706B (en) * 2013-09-02 2016-01-27 吉林大学 A kind of titanium surface directly generates the preparation method of hydroxyl apatite bioceramic film
CN104695005B (en) * 2015-03-13 2018-02-27 河北工业大学 A kind of method that Titanium base surface prepares orderly micro-nano structure
CN105671612B (en) * 2015-08-21 2017-12-29 北京大学第三医院 Porous metal implants and preparation method with differential arc oxidation coating
CN105624762B (en) * 2016-01-15 2018-01-12 厦门大学 Method for preparing bioactive composite coating on surface of titanium or titanium alloy
FR3059342B1 (en) * 2016-11-28 2022-06-17 Institut De Recherche Tech Materiaux Metallurgie Procedes PARTS WITH CERAMIC COATING ON TITANIUM OR TITANIUM ALLOY SURFACES, OBTAINED BY MICRO-ARC ANODIZATION AND ELECTROLYTE SUITABLE FOR OBTAINING THEM
DE102017111784A1 (en) * 2017-05-30 2018-12-06 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Coated substrate with titanium-containing coating and modified titanium oxide coating
CN109609906B (en) * 2019-01-29 2021-04-02 西北工业大学 Plasma discharge coupling modification method for improving wear resistance of titanium alloy
CN110484956A (en) * 2019-08-13 2019-11-22 洛阳双瑞精铸钛业有限公司 A kind of preparation method of titanium alloy drilling well workpiece high-wearing feature differential arc oxidation layer
CN111020545A (en) * 2019-12-13 2020-04-17 陕西易莱德新材料科技有限公司 Titanium material surface treatment method
CN111330580B (en) * 2020-03-10 2021-05-28 中国科学院山西煤炭化学研究所 Acid-resistant catalyst, preparation method thereof and application of acid-resistant catalyst in water-phase hydrogenation production of succinic acid
CN111467577B (en) * 2020-04-21 2023-01-17 王永芝 Medical metal bone implant material
CN113186579B (en) * 2021-04-20 2024-02-27 北京科技大学 Titanium alloy oral cavity restoration surface whitening self-cleaning coating and preparation method thereof
GB2613562A (en) * 2021-12-03 2023-06-14 Keronite International Ltd Use of chelating agents in plasma electrolytic oxidation processes
CN113981296B (en) * 2021-12-24 2022-03-22 北京钢研高纳科技股份有限公司 Ti2AlNb-based alloy and preparation method and application thereof
CN114507893B (en) * 2022-01-14 2023-11-24 电子科技大学 Electrolyte for high-hardness wear-resistant micro-arc oxidation coating on tantalum alloy surface and preparation method thereof
CN114507892B (en) * 2022-01-14 2023-11-24 电子科技大学 Tantalum alloy self-lubricating wear-resistant antifriction composite coating and preparation method thereof
CN114703530B (en) * 2022-04-28 2023-08-25 徐州工程学院 Method for compositely constructing samarium-doped hydroxyapatite gradient coating on magnesium alloy surface by utilizing electrophoresis/micro-arc oxidation technology
CN115970057B (en) * 2022-09-09 2024-05-28 浙江科惠医疗器械股份有限公司 Petal-shaped TiO2Preparation method of nano-pore antibacterial coating

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD246028A1 (en) * 1986-02-12 1987-05-27 Karl Marx Stadt Tech Hochschul CERAMIZED METAL IMPLANT
HU213001B (en) * 1992-04-10 1997-01-28 Tavkoezlesi Innovacios Rt Process for obtaining tissue-protective deposit on implants prepared from titanium and/or titanium-base microalloy
CA2150036C (en) * 1993-11-09 2001-07-10 Tadashi Kokubo A material for a bone substitute and the manufacturing method thereof
SE514202C2 (en) * 1999-05-31 2001-01-22 Nobel Biocare Ab Layers arranged on bone or tissue structure implants and such implants and methods for applying the layer
SE519531C2 (en) * 2001-07-04 2003-03-11 Nobel Biocare Ab Implants including pore arrangements coated with calcium phosphate
KR100714244B1 (en) * 2004-04-26 2007-05-02 한국기계연구원 Osseoinductive metal implants for a living body and producing method thereof

Also Published As

Publication number Publication date
WO2007090433A3 (en) 2007-11-01
WO2007090433A2 (en) 2007-08-16

Similar Documents

Publication Publication Date Title
WO2007090433A8 (en) Purified oxides with novel morphologies formed from ti-alloys
Tsuchiya et al. Nanotube oxide coating on Ti–29Nb–13Ta–4.6 Zr alloy prepared by self-organizing anodization
RS20050552A (en) Thermostable and corrosion- resistant cast nickel-chromium alloy
SI1979512T1 (en) Crucible for the treatment of molten silicon and process for its manufacture
Jin et al. Thermal stability of titania films prepared on titanium by micro-arc oxidation
WO2004037714A3 (en) Carbon nanoparticles and composite particles and process of manufacture
AU2002366728A8 (en) Surface modified zinc oxide for the production of nanoparticulate dispersions
TW200611984A (en) Steel band for doctor blades, coater blades and creping blades and powder metallurgical method for the manufacture thereof
WO2008041455A1 (en) Method for coating ceramic film on metal, electrolysis solution for use in the method, and ceramic film and metal material
FR2852263B1 (en) PROCESS FOR THE PREPARATION OF NANOSTRUCTURE METAL ALLOYS HAVING AN INCREASED NITRIDE CONTENT
WO2007130483A3 (en) Tantalum powder with smooth surface and methods of manufacturing same
TWI622496B (en) Article with metal oxide film
WO2008037506A8 (en) Uses of self-organized needle-type nanostructures
CN101942688A (en) Composite oxidation technology for medicinal titanium alloy
WO2007137772A3 (en) Bone implant made of a titanium alloy, and method for the production thereof
WO2013162658A3 (en) Oxygen-enriched ti-6ai-4v alloy and process for manufacture
WO2005098054A8 (en) Method in connection with steel production
WO2010001064A3 (en) Fused grains of oxides comprising al, ti and mg and ceramic products comprising such grains
Li et al. Effect of temperature on carbothermic reduction of ilmenite
TW200732288A (en) Method for producing cycloalkanol and/or cycloalkanone
KR101961856B1 (en) Manufacturing method of ceramic-metal tile
WO2004005306A3 (en) Metallic object with a nucleic acid coating and derivatives thereof and method for producing said object
Wang et al. Microstructure and Mechanical Properties of Ceramic Coatings Produced on Ti 6 Al 4 V by Micro-arc Oxidation in Na 2 SiO 3 Solution
Wang et al. Formation thermodynamics of titanium oxide during solidification of low carbon steel containing titanium.
Shchetkovskiy et al. Electroforming of near-net shapes of iridium

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application
NENP Non-entry into the national phase in:

Ref country code: DE

122 Ep: pct app. not ent. europ. phase

Ref document number: 06723352

Country of ref document: EP

Kind code of ref document: A2