WO2007089926A3 - Oxcarbazepine pharmaceutical formulation and its method of preparation, wherein oxcarbazepine has a broad and multi-modal particle size distribution - Google Patents
Oxcarbazepine pharmaceutical formulation and its method of preparation, wherein oxcarbazepine has a broad and multi-modal particle size distribution Download PDFInfo
- Publication number
- WO2007089926A3 WO2007089926A3 PCT/US2007/002882 US2007002882W WO2007089926A3 WO 2007089926 A3 WO2007089926 A3 WO 2007089926A3 US 2007002882 W US2007002882 W US 2007002882W WO 2007089926 A3 WO2007089926 A3 WO 2007089926A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- oxcarbazepine
- particle size
- size distribution
- broad
- preparation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07762826A EP2029118A2 (en) | 2006-01-31 | 2007-01-31 | Oxcarbazepine pharmaceutical formulation and its method of preparation, wherein oxcarbazepine has a broad and multi-modal particle size distribution |
JP2008509257A JP2008540346A (en) | 2006-01-31 | 2007-01-31 | Pharmaceutical formulation of oxcarbazepine and preparation method thereof |
AU2007211210A AU2007211210A1 (en) | 2006-01-31 | 2007-01-31 | Oxcarbazepine pharmaceutical formulation and its method of preparation, wherein oxcarbazepine has a broad and multi-modal particle size distribution |
CA002634879A CA2634879A1 (en) | 2006-01-31 | 2007-01-31 | Pharmaceutical formulations of oxcarbazepine and methods for its preparation |
IL191922A IL191922A0 (en) | 2006-01-31 | 2008-06-03 | Pharmaceutical formulations of oxcarbazepine and methods for its preparation |
Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US76413406P | 2006-01-31 | 2006-01-31 | |
US60/764,134 | 2006-01-31 | ||
US11/350,606 US20070178164A1 (en) | 2006-01-31 | 2006-02-08 | Pharmaceutical formulations of oxcarbazepine and methods for its preparation |
US11/350,606 | 2006-02-08 | ||
US86033306P | 2006-11-20 | 2006-11-20 | |
US60/860,333 | 2006-11-20 | ||
US89736107P | 2007-01-24 | 2007-01-24 | |
US60/897,361 | 2007-01-24 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2007089926A2 WO2007089926A2 (en) | 2007-08-09 |
WO2007089926A3 true WO2007089926A3 (en) | 2008-12-24 |
Family
ID=38328068
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2007/002882 WO2007089926A2 (en) | 2006-01-31 | 2007-01-31 | Oxcarbazepine pharmaceutical formulation and its method of preparation, wherein oxcarbazepine has a broad and multi-modal particle size distribution |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP2029118A2 (en) |
JP (1) | JP2008540346A (en) |
AU (1) | AU2007211210A1 (en) |
CA (1) | CA2634879A1 (en) |
IL (1) | IL191922A0 (en) |
WO (1) | WO2007089926A2 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2630240A1 (en) * | 2006-01-31 | 2007-08-09 | Teva Pharmaceutical Industries Ltd. | Oxcarbazepine pharmaceutical formulation and its method of preparation, wherein oxcarbazepine has a broad and multi-modal particle size distribution |
US8372431B2 (en) | 2007-10-26 | 2013-02-12 | Bial-Portela & C.A., S.A. | Pharmaceutical composition comprising licarbazepine acetate |
ES2761265T3 (en) * | 2013-03-15 | 2020-05-19 | Aprecia Pharmaceuticals LLC | Rapidly dispersible oxcarbazepine dosage form |
JP6843498B2 (en) * | 2015-10-14 | 2021-03-17 | Eaファーマ株式会社 | Tablets, solid dispersion granules and methods for producing them |
Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5354563A (en) * | 1985-07-15 | 1994-10-11 | Research Development Corp. Of Japan | Water dispersion containing ultrafine particles of organic compounds |
US5472714A (en) * | 1993-09-08 | 1995-12-05 | Ciba-Geigy Corporation | Double-layered oxcarbazepine tablets |
WO1998035681A1 (en) * | 1997-02-14 | 1998-08-20 | Novartis Ag | Oxacarbazepine film-coated tablets |
WO2002094774A2 (en) * | 2001-05-18 | 2002-11-28 | Ranbaxy Laboratories Limited | Oxcarbazepine dosage forms |
US20040142033A1 (en) * | 2002-05-31 | 2004-07-22 | Desitin Arzneimittel Gmbh | Pharmaceutical composition, containing oxcarbazepine with sustained release of an active-ingredient |
WO2006046105A1 (en) * | 2004-10-25 | 2006-05-04 | Ranbaxy Laboratories Limited | Oxcarbazepine dosage forms |
WO2007007182A2 (en) * | 2005-07-08 | 2007-01-18 | Aurobindo Pharma Limited | Solid and liquid dosage forms of an antiepileptic agent |
EP1815849A1 (en) * | 2006-01-31 | 2007-08-08 | Teva Pharmaceutical Industries Ltd | Oxcarbazepine pharmaceutical formulation and its method of preparation, wherein oxcarbazepine has a broad and multi-modal particle size distribution |
WO2007121523A1 (en) * | 2006-04-21 | 2007-11-01 | Alphapharm Pty Ltd | Pharmaceutical compositions of oxcarbazepine with a median particle size of 15 to 30 microns |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3170069B2 (en) * | 1992-10-06 | 2001-05-28 | 日水製薬株式会社 | Sustained release granules |
GB9925962D0 (en) * | 1999-11-02 | 1999-12-29 | Novartis Ag | Organic compounds |
GB0221956D0 (en) * | 2002-09-20 | 2002-10-30 | Novartis Ag | Organic compounds |
-
2007
- 2007-01-31 CA CA002634879A patent/CA2634879A1/en not_active Abandoned
- 2007-01-31 WO PCT/US2007/002882 patent/WO2007089926A2/en active Application Filing
- 2007-01-31 JP JP2008509257A patent/JP2008540346A/en active Pending
- 2007-01-31 EP EP07762826A patent/EP2029118A2/en not_active Withdrawn
- 2007-01-31 AU AU2007211210A patent/AU2007211210A1/en not_active Abandoned
-
2008
- 2008-06-03 IL IL191922A patent/IL191922A0/en unknown
Patent Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5354563A (en) * | 1985-07-15 | 1994-10-11 | Research Development Corp. Of Japan | Water dispersion containing ultrafine particles of organic compounds |
US5472714A (en) * | 1993-09-08 | 1995-12-05 | Ciba-Geigy Corporation | Double-layered oxcarbazepine tablets |
WO1998035681A1 (en) * | 1997-02-14 | 1998-08-20 | Novartis Ag | Oxacarbazepine film-coated tablets |
WO2002094774A2 (en) * | 2001-05-18 | 2002-11-28 | Ranbaxy Laboratories Limited | Oxcarbazepine dosage forms |
US20040142033A1 (en) * | 2002-05-31 | 2004-07-22 | Desitin Arzneimittel Gmbh | Pharmaceutical composition, containing oxcarbazepine with sustained release of an active-ingredient |
WO2006046105A1 (en) * | 2004-10-25 | 2006-05-04 | Ranbaxy Laboratories Limited | Oxcarbazepine dosage forms |
WO2007007182A2 (en) * | 2005-07-08 | 2007-01-18 | Aurobindo Pharma Limited | Solid and liquid dosage forms of an antiepileptic agent |
EP1815849A1 (en) * | 2006-01-31 | 2007-08-08 | Teva Pharmaceutical Industries Ltd | Oxcarbazepine pharmaceutical formulation and its method of preparation, wherein oxcarbazepine has a broad and multi-modal particle size distribution |
WO2007121523A1 (en) * | 2006-04-21 | 2007-11-01 | Alphapharm Pty Ltd | Pharmaceutical compositions of oxcarbazepine with a median particle size of 15 to 30 microns |
Also Published As
Publication number | Publication date |
---|---|
EP2029118A2 (en) | 2009-03-04 |
WO2007089926A2 (en) | 2007-08-09 |
CA2634879A1 (en) | 2007-08-09 |
IL191922A0 (en) | 2009-08-03 |
JP2008540346A (en) | 2008-11-20 |
AU2007211210A1 (en) | 2007-08-09 |
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