WO2007088446A3 - A process and a reagent kit for the examination of the metabolic state related to the carbohydrate and lipid metabolism of a human organism - Google Patents

A process and a reagent kit for the examination of the metabolic state related to the carbohydrate and lipid metabolism of a human organism Download PDF

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Publication number
WO2007088446A3
WO2007088446A3 PCT/IB2007/000201 IB2007000201W WO2007088446A3 WO 2007088446 A3 WO2007088446 A3 WO 2007088446A3 IB 2007000201 W IB2007000201 W IB 2007000201W WO 2007088446 A3 WO2007088446 A3 WO 2007088446A3
Authority
WO
WIPO (PCT)
Prior art keywords
carbohydrate
examination
lipid metabolism
human organism
state related
Prior art date
Application number
PCT/IB2007/000201
Other languages
French (fr)
Other versions
WO2007088446A2 (en
Inventor
Attila Kolonics
Kalman Tory
Nagy Peter Literati
Laszlo Koranyi
Janos Egri
Original Assignee
N Gene Res Lab Inc
Attila Kolonics
Kalman Tory
Nagy Peter Literati
Laszlo Koranyi
Janos Egri
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by N Gene Res Lab Inc, Attila Kolonics, Kalman Tory, Nagy Peter Literati, Laszlo Koranyi, Janos Egri filed Critical N Gene Res Lab Inc
Publication of WO2007088446A2 publication Critical patent/WO2007088446A2/en
Publication of WO2007088446A3 publication Critical patent/WO2007088446A3/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/04—Endocrine or metabolic disorders

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The invention refers to a process for the examination of the metabolic state related to the carbohydrate and lipid metabolism of a human organism, thus, for the detection of the healthy or ill state. According to the invention, the number and/or one or more characteristics of the mitochondria that are present in the leukocyte cells separated from the blood sample of the individual to be examined and/or the amount of nitric oxide produced in the leucocyte cells are determined in a manner known per se, and, based on the values obtained, the state of the individual examined is evaluated.
PCT/IB2007/000201 2006-02-02 2007-01-30 A process and a reagent kit for the examination of the metabolic state related to the carbohydrate and lipid metabolism of a human organism WO2007088446A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HUP0600082 2006-02-02
HU0600082A HUP0600082A2 (en) 2006-02-02 2006-02-02 Process and testset for examination of the metabolic state of the organism in connection with carbohydrate - and fatmetabolism

Publications (2)

Publication Number Publication Date
WO2007088446A2 WO2007088446A2 (en) 2007-08-09
WO2007088446A3 true WO2007088446A3 (en) 2007-11-29

Family

ID=89986557

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2007/000201 WO2007088446A2 (en) 2006-02-02 2007-01-30 A process and a reagent kit for the examination of the metabolic state related to the carbohydrate and lipid metabolism of a human organism

Country Status (2)

Country Link
HU (1) HUP0600082A2 (en)
WO (1) WO2007088446A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111579763B (en) * 2020-04-09 2023-04-07 北京博瑞世安科技有限公司 Method for detecting respiratory function of leucocyte mitochondria and method for detecting kidney yin deficiency

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2021619C1 (en) * 1991-11-25 1994-10-15 Ирина Иосифовна Влох Method of insulin-resistance diagnosis in patients with depressive states
US6232078B1 (en) * 1997-02-21 2001-05-15 Hong-Kyu Lee Method for diagnosing preclinical diabetes by quantification of mitochondrial DNA in peripheral blood
US20030235812A1 (en) * 1999-04-30 2003-12-25 Mitokor Indicators of altered mitochondrial function in predictive methods for determining risk of type 2 diabetes mellitus

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2021619C1 (en) * 1991-11-25 1994-10-15 Ирина Иосифовна Влох Method of insulin-resistance diagnosis in patients with depressive states
US6232078B1 (en) * 1997-02-21 2001-05-15 Hong-Kyu Lee Method for diagnosing preclinical diabetes by quantification of mitochondrial DNA in peripheral blood
US20030235812A1 (en) * 1999-04-30 2003-12-25 Mitokor Indicators of altered mitochondrial function in predictive methods for determining risk of type 2 diabetes mellitus

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; June 2006 (2006-06-01), KOLONICS ATTILA ET AL: "Mitochondrial status of lymphocytes shows correlation with metabolic state", XP009087496, Database accession no. PREV200600669552 *
DIABETES, vol. 55, no. Suppl. 1, June 2006 (2006-06-01), 66TH ANNUAL MEETING OF THE AMERICAN-DIABETES-ASSOCIATION; WASHINGTON, DC, USA; JUNE 09 -13, 2006, pages A143 - A144, ISSN: 0012-1797 *
NAGY GYORGY ET AL: "Nitric oxide-dependent mitochondrial biogenesis generates Ca2+ signaling profile of lupus T cells", JOURNAL OF IMMUNOLOGY, vol. 173, no. 6, 15 September 2004 (2004-09-15), pages 3676 - 3683, XP002444870, ISSN: 0022-1767 *

Also Published As

Publication number Publication date
WO2007088446A2 (en) 2007-08-09
HUP0600082A2 (en) 2007-09-28
HU0600082D0 (en) 2006-03-28

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