WO2007086077A3 - A novel one pot process for preparation of pantoprazole sodium sesquihydrate - Google Patents

A novel one pot process for preparation of pantoprazole sodium sesquihydrate Download PDF

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Publication number
WO2007086077A3
WO2007086077A3 PCT/IN2006/000360 IN2006000360W WO2007086077A3 WO 2007086077 A3 WO2007086077 A3 WO 2007086077A3 IN 2006000360 W IN2006000360 W IN 2006000360W WO 2007086077 A3 WO2007086077 A3 WO 2007086077A3
Authority
WO
WIPO (PCT)
Prior art keywords
novel
preparation
pot process
pantoprazole sodium
sodium sesquihydrate
Prior art date
Application number
PCT/IN2006/000360
Other languages
French (fr)
Other versions
WO2007086077A2 (en
Inventor
Arul Ramakrishnan
Muralidhar Sonar Tryambak
Mokal Asawari
Original Assignee
Unichem Lab Ltd
Arul Ramakrishnan
Muralidhar Sonar Tryambak
Mokal Asawari
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unichem Lab Ltd, Arul Ramakrishnan, Muralidhar Sonar Tryambak, Mokal Asawari filed Critical Unichem Lab Ltd
Publication of WO2007086077A2 publication Critical patent/WO2007086077A2/en
Publication of WO2007086077A3 publication Critical patent/WO2007086077A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

The present invention provides a novel one-pot process for preparation of Pantoprazole sodium sesquihydrate Form-I in the pure form without isolating the pantoprazole base.
PCT/IN2006/000360 2006-01-24 2006-09-12 A novel one pot process for preparation of pantoprazole sodium sesquihydrate WO2007086077A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN107/MUM/2006 2006-01-24
IN107MU2006 2006-01-24

Publications (2)

Publication Number Publication Date
WO2007086077A2 WO2007086077A2 (en) 2007-08-02
WO2007086077A3 true WO2007086077A3 (en) 2009-04-30

Family

ID=38309608

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2006/000360 WO2007086077A2 (en) 2006-01-24 2006-09-12 A novel one pot process for preparation of pantoprazole sodium sesquihydrate

Country Status (1)

Country Link
WO (1) WO2007086077A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7507829B2 (en) 2002-12-19 2009-03-24 Teva Pharmaceuticals Industries, Ltd Solid states of pantoprazole sodium, processes for preparing them and processes for preparing known pantoprazole sodium hydrates
MXPA05013316A (en) 2003-06-10 2006-03-17 Teva Pharma Process for preparing 2-[(pyridinyl)methyl]sulfinyl-substituted benzimidazoles and novel chlorinated derivatives of pantoprazole.
US20100210847A1 (en) * 2007-07-17 2010-08-19 Ranbaxy Laboratories Limited Process for the preparation of pantoprazole sodium and pantoprazole sodium sesquihydrate
WO2010134099A1 (en) * 2009-05-21 2010-11-25 Cadila Healthcare Limited One pot process for preparing omeprazole and related compounds
CN102584790B (en) * 2011-12-31 2014-04-02 江苏奥赛康药业股份有限公司 S-pantoprazole sodium trihydrate, and preparation method and application thereof
CN111057044A (en) * 2019-12-19 2020-04-24 北京民康百草医药科技有限公司 Preparation method of single crystal form of pantoprazole sodium sesquihydrate

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0166287A1 (en) * 1984-06-16 1986-01-02 Byk Gulden Lomberg Chemische Fabrik GmbH Dialkoxyridines, process for their preparation, their application and medicaments containing them
WO2004080961A2 (en) * 2003-03-12 2004-09-23 Teva Pharmaceutical Industries Ltd. Crystalline and amorphous solids of pantoprazole and processes for their preparation
WO2004111029A2 (en) * 2003-06-10 2004-12-23 Teva Pharmaceutical Industries Ltd. Process for preparing 2-[(pyridinyl)methyl]sulfinyl-substituted benzimidazoles and novel chlorinated derivatives of pantoprazole
WO2005077936A1 (en) * 2004-02-11 2005-08-25 Ulkar Kimya Sanayii Ve Ticaret A.S. Pyridine benzimidazole sulfoxides with high purity

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0166287A1 (en) * 1984-06-16 1986-01-02 Byk Gulden Lomberg Chemische Fabrik GmbH Dialkoxyridines, process for their preparation, their application and medicaments containing them
WO2004080961A2 (en) * 2003-03-12 2004-09-23 Teva Pharmaceutical Industries Ltd. Crystalline and amorphous solids of pantoprazole and processes for their preparation
WO2004111029A2 (en) * 2003-06-10 2004-12-23 Teva Pharmaceutical Industries Ltd. Process for preparing 2-[(pyridinyl)methyl]sulfinyl-substituted benzimidazoles and novel chlorinated derivatives of pantoprazole
WO2005077936A1 (en) * 2004-02-11 2005-08-25 Ulkar Kimya Sanayii Ve Ticaret A.S. Pyridine benzimidazole sulfoxides with high purity

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
V. T. MATHAD ET AL.: "An Improved and Single-Pot Process for the Production of Pantoprazole Substantially Free from Sulfone Impurity", ORGANIC PROCESS RESEARCH & DEVELOPMENT, vol. 8, 2004, pages 266 - 270, XP055247967, DOI: doi:10.1021/op034157y *

Also Published As

Publication number Publication date
WO2007086077A2 (en) 2007-08-02

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