WO2007084858A3 - Biomimetic hydroxyapatite synthesis - Google Patents

Biomimetic hydroxyapatite synthesis Download PDF

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Publication number
WO2007084858A3
WO2007084858A3 PCT/US2007/060505 US2007060505W WO2007084858A3 WO 2007084858 A3 WO2007084858 A3 WO 2007084858A3 US 2007060505 W US2007060505 W US 2007060505W WO 2007084858 A3 WO2007084858 A3 WO 2007084858A3
Authority
WO
WIPO (PCT)
Prior art keywords
hydroxyapatite particles
amounts
amount
produce
ion source
Prior art date
Application number
PCT/US2007/060505
Other languages
French (fr)
Other versions
WO2007084858A2 (en
Inventor
Richard E Riman
Christina Sever
Original Assignee
Univ Rutgers
Richard E Riman
Christina Sever
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Rutgers, Richard E Riman, Christina Sever filed Critical Univ Rutgers
Priority to EP07718197A priority Critical patent/EP1981514A2/en
Priority to AU2007205961A priority patent/AU2007205961B2/en
Publication of WO2007084858A2 publication Critical patent/WO2007084858A2/en
Publication of WO2007084858A3 publication Critical patent/WO2007084858A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/42—Phosphorus; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/12—Phosphorus-containing materials, e.g. apatite

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)

Abstract

A method for preparing nanoscale hydroxyapatite particles by combining an amount of a calcium ion source, which includes calcium acetate, and an amount of a phosphate ion source, wherein the amounts are sufficient to produce nanoscale hydroxyapatite particles and the amounts are combined under ambient conditions to produce the hydroxyapatite particles. Nanoscale hydroxyapatite particles are also presented.
PCT/US2007/060505 2006-01-12 2007-01-12 Biomimetic hydroxyapatite synthesis WO2007084858A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP07718197A EP1981514A2 (en) 2006-01-12 2007-01-12 Biomimetic hydroxyapatite synthesis
AU2007205961A AU2007205961B2 (en) 2006-01-12 2007-01-12 Biomimetic hydroxyapatite synthesis

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75820706P 2006-01-12 2006-01-12
US60/758,207 2006-01-12

Publications (2)

Publication Number Publication Date
WO2007084858A2 WO2007084858A2 (en) 2007-07-26
WO2007084858A3 true WO2007084858A3 (en) 2007-11-29

Family

ID=38288352

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/060505 WO2007084858A2 (en) 2006-01-12 2007-01-12 Biomimetic hydroxyapatite synthesis

Country Status (3)

Country Link
EP (1) EP1981514A2 (en)
AU (1) AU2007205961B2 (en)
WO (1) WO2007084858A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8287914B2 (en) 2006-01-12 2012-10-16 Rutgers, The State University Of New Jersey Biomimetic hydroxyapatite synthesis
PL210026B1 (en) * 2009-03-17 2011-11-30 Akademia Górniczo Hutnicza Im Stanisława Staszica Method of manufacturing the high-porous, bioactive calcium phosphate implant material
WO2011124234A1 (en) * 2010-04-07 2011-10-13 Eman Ismail Abd El-Gawad Repair of fragmented dna and treatment of heavy metal intoxication by intravenous injection of nano-hydroxyapatite
KR20180089389A (en) 2015-09-25 2018-08-08 클린 월드 테크놀로지스 엘티디. Preparation of calcium phosphate composition
CN106824236A (en) * 2017-02-21 2017-06-13 西华师范大学 Caesium or the hydroxyapatite catalyst of calcic of potassium doping and its preparation method and application
CN110775953B (en) * 2019-11-27 2023-03-31 中山市科信生物技术有限公司 Method for synthesizing thermodynamically stable hydroxyapatite with microscopic kinetic reaction limitation
CN112875665B (en) * 2021-02-07 2022-11-01 吉林大学 Hydroxyapatite microspheres for injection filling preparation and preparation method thereof
CN113797395B (en) * 2021-09-17 2023-02-21 北京爱康宜诚医疗器材有限公司 Nano hydroxyapatite/block copolymer composite material and preparation method thereof
CN115557480A (en) * 2022-10-28 2023-01-03 南京市儿童医院 Synthesis method of cobalt-doped hydroxyapatite microspheres
CN116832223B (en) * 2023-07-27 2024-01-30 重庆生物智能制造研究院 Medical absorbable calcium phosphate salt/polyester composite material and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6013591A (en) * 1997-01-16 2000-01-11 Massachusetts Institute Of Technology Nanocrystalline apatites and composites, prostheses incorporating them, and method for their production
US6387414B1 (en) * 1999-08-05 2002-05-14 Nof Corporation Method for preparing hydroxyapatite composite and biocompatible material
US6921544B2 (en) * 2001-03-06 2005-07-26 Rutgers, The State University Magnesium-substituted hydroxyapatites

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE527610C2 (en) * 2004-06-15 2006-04-25 Promimic Ab Process for the preparation of synthetic crystalline calcium phosphate in nano size
WO2007009477A1 (en) * 2005-07-21 2007-01-25 Lisopharm Ag Method for producing hydroxyapatite particles, in particular subnanodisperse hydroxyapatite particles in a matrix

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6013591A (en) * 1997-01-16 2000-01-11 Massachusetts Institute Of Technology Nanocrystalline apatites and composites, prostheses incorporating them, and method for their production
US6387414B1 (en) * 1999-08-05 2002-05-14 Nof Corporation Method for preparing hydroxyapatite composite and biocompatible material
US6921544B2 (en) * 2001-03-06 2005-07-26 Rutgers, The State University Magnesium-substituted hydroxyapatites

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
RIMAN ET AL.: "Solution Synthesis of Hydroxyapatite Designer Particulates", SOLID STATE IONICS, vol. 151, 2002, pages 393 - 402, XP004393814 *

Also Published As

Publication number Publication date
EP1981514A2 (en) 2008-10-22
WO2007084858A2 (en) 2007-07-26
AU2007205961A1 (en) 2007-07-26
AU2007205961B2 (en) 2013-03-14

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