WO2007081311A1 - Lentille intraoculaire d’accommodation - Google Patents

Lentille intraoculaire d’accommodation Download PDF

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Publication number
WO2007081311A1
WO2007081311A1 PCT/US2006/000370 US2006000370W WO2007081311A1 WO 2007081311 A1 WO2007081311 A1 WO 2007081311A1 US 2006000370 W US2006000370 W US 2006000370W WO 2007081311 A1 WO2007081311 A1 WO 2007081311A1
Authority
WO
WIPO (PCT)
Prior art keywords
intraocular lens
arms
elongated member
optical element
capsular bag
Prior art date
Application number
PCT/US2006/000370
Other languages
English (en)
Inventor
Medhi Vazeen
Original Assignee
Medhi Vazeen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medhi Vazeen filed Critical Medhi Vazeen
Priority to PCT/US2006/000370 priority Critical patent/WO2007081311A1/fr
Publication of WO2007081311A1 publication Critical patent/WO2007081311A1/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/14Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16Intraocular lenses
    • A61F2/1613Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/14Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16Intraocular lenses
    • A61F2/1613Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A61F2/1624Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus having adjustable focus; power activated variable focus means, e.g. mechanically or electrically by the ciliary muscle or from the outside
    • A61F2/1629Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus having adjustable focus; power activated variable focus means, e.g. mechanically or electrically by the ciliary muscle or from the outside for changing longitudinal position, i.e. along the visual axis when implanted
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/14Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16Intraocular lenses
    • A61F2002/1681Intraocular lenses having supporting structure for lens, e.g. haptics
    • A61F2002/1683Intraocular lenses having supporting structure for lens, e.g. haptics having filiform haptics

Definitions

  • the present invention relates to a novel and useful accommodating intraocular lens .
  • Intraocular lenses have been implanted in eyes following cataract surgery for a number of years .
  • a conventional intraocular lens is intended to replace the natural lens which has been removed due to such cataract condition.
  • Surgical techniques have evolved over the years to performance of an extra-capsular procedure. That is to say, the capsule which held the removed natural lens is retained in the posterior chamber of the eye, minus an excised frontal portion. The result is a capsular bag connected to the ciliary muscle by a multiplicity of zonules, commonly referred to as the zonular system. In this manner, vitreous humor is maintained in the posterior chamber of the eye and the inserted intraocular lens is confined or fixed in the eye for use.
  • intraocular lenses do not provide the patient with near and far vision, since intraocular lenses do not react to the contraction and relaxation of the zonular system. This ability is normally referred to as "accommodation".
  • a patient must be fitted with corrective glasses in order to perform tasks associated with near and far vision, e.g. reading and driving a vehicle.
  • United States Patents 4,485,499 and 6,200,343 Bl show intraocular lenses with resilient curved open loops to fix and intraocular lens in the posterior chamber of the eye .
  • Patent 5,133,750 shows an intraocular lens constructed of synthetic sapphire which includes a quartet of arms to hold the lens in place.
  • United States Patent 5,628,798 teaches an adjustable and removable intraocular lens having a portion which may be changed, adjusted, or modified after insertion.
  • United States Patent 6,117,171 illustrates an encapsulated accommodating intraocular lens having two spaces separated by a transparent flexible membrane. Altering the curvature of the membrane alters the overall optical power of the lens .
  • United States Patent 4,888,012 shows an intraocular lens assembly in which the lens is formed of elastic material which is extended or compressed to change the shape of the optical portion to accommodate with alterations in the tension of the ciliary muscle of the eye.
  • United States Patent 6,176,878 Bl poses an accommodating intraocular lens having an optic that is connected to a flexible disc that moves the optic inwardly and outwardly according to changes in the tension of the ciliary muscle.
  • a novel and useful accommodating intraocular lens is herein provided.
  • the lens of the present invention utilizes an optical element which is chosen to correct the vision of a particular individual following removal of the natural lens possessing a cataract condition and performance of an anterior capsulotomy.
  • Support means is employed for positioning the optical element in the open capsular bag at the posterior chamber of the eye .
  • Such support means may take the form of an elongated member which extends along the periphery of the interior of the open capsular bag.
  • the elongated member may be curved and terminate, at its end portions, with an enlargement.
  • Such support means may include a pair of such elements diametrically opposed to one another within the capsular bag.
  • the support means may also be formed with a plurality of flanges which are intended to extend from the elongated member in the vicinity of the anterior surface of the capsular bag. Bonding of the support means to the capsular bag occurs through the natural growth of fibrous tissue.
  • Adjustment means is also included in the present invention for effecting movement of the optical element anteriorly and posteriorly.
  • the adjustment means utilizes a plurality of rotatable flexible arms which depend from the elements of the support means .
  • the plurality of rotatable flexible arms may be curved and lie spaced from one another about the peripheral portion of the optical element.
  • the plurality of rotatable arms are linked to the open capsular bag held by the zonular system of the eye. Such linking takes place through the support means elements such that forces exerted by the capsular bag on the support means is transferred to the plurality of rotatable arms. Relaxation of the zonular system will cause the capsular bag to collapse and force the rotation of the plurality of arms to move the optical element anteriorly.
  • Another object of the present invention is to provide an accommodating intraocular lens which can be easily implanted in an eye following extra-capsular cataract surgery.
  • a further object of the present invention is to provide an accommodating intraocular lens which prevents secondary surgical procedures to correct focusing characteristics of intraocular lenses.
  • Another object of the present invention is to provide an accommodating intraocular lens which eliminates the need for spectacles to provide a patient receiving an implanted intraocular lens with the ability of attain near and far vision ability.
  • Yet another object of the present invention is to provide an accommodating intraocular lens which correctly and accurately transmits the force or movements of the capsular bag originating in the zonular system to be transmitted to the optical component of the lens of the present invention.
  • Fig. 1 is a sectional view of the intraocular lens of the present invention implanted in an eye.
  • Fig. 2 is a front elevational view of the implanted lens depicted in Fig. 1.
  • Fig. 3 is a sectional schematic view showing anterior movement of the optical element of the lens of the present invention with relaxation of the zonules.
  • Fig. 4 is a front elevational schematic view of the lens moved anteriorly as shown in Fig. 3.
  • Fig. 5 is a sectional schematic view of the lens of the present invention moving posteriorly with tensioning of the zonules .
  • Fig. 6 is a schematic front elevational view of the lens moved posteriorly as depicted in Fig. 5.
  • Intraocular lens 10 includes as one of its portions an optical element 12.
  • Optical element 12 takes the form of a crystalline lens composed of any suitable tissue compatible material such as polymethyl methacrylate, polysulfone, hydrogel, silicone, and the like.
  • Optical element 12 is employed to replace the natural lens which has been removed as a result of cataract surgery.
  • the optical properties of element 12 are chosen to correct the vision of a patient in a normal range.
  • Prior art intraocular lenses using similar optical elements require the patient to be fitted with corrective glasses in order to achieve near and far vision.
  • Optical element 12 is shown in Fig. 1 as being implanted in eye 14, specifically in posterior chamber 16 thereof.
  • Eye 14 includes cornea 18 and iris 20 which generally provide the confines to anterior chamber 22.
  • Pupil 24 serves as the adjustable circular opening between anterior chamber 22 and posterior chamber 16 which permits light passing through cornea 18 to travel through optical element 12 and, eventually, to the retina (not shown) .
  • Capsular bag 26 represents the remnant of the natural capsule and includes an opening 28 adjacent pupil 24.
  • Capsular bag 26 is employed to hold or fixate intraocular lens 10 into prevent the movement of vitreous humor normally found in the posterior anterior chamber 16.
  • Capsular bag 26 is resilient and is supported in place by zonules 32.
  • Zonules 32 directly connect to ciliary muscle 34.
  • Ciliary muscle 34 and zonules 32 comprise the zonular system 36 which, in turn, stretches and collapses capsular bag 26 during the natural focusing process of eye 14.
  • intraocular lens 10 is depicted as lying within chamber 38 of capsular bag 26.
  • Chamber 38 is formed by inner wall 40 of capsular bag 26.
  • Support means 42 includes elongated curved members 44 and 46 which are of generally semicircular configuration. Enlargements 48, 50, 52 and 54 cap the ends of elongated members 44 and 46.
  • a plurality of flanges 56 depicted as circular springs in Fig. 2, are connected to elongated members 44 and 46 such that certain of such flanges lie directly against wall 40 of capsular bag 26.
  • Adjustment means 58 is also illustrated in Fig. 2.
  • Adjustment means takes the form of a plurality of rotatable flexible arms 60 which link elongated members 44 and 46 to optical element 12. It should be realized that plurality of rotatable arms also serve as a portion of support means 42 for optical element 12.
  • plurality of rotatable arms 60 include a first set 62 associated with elongated member 44 and a second set 64 associated with elongated member 46. Although five rotatable arms are indicated as being associated with each elongated member, 44, 46 a lesser or greater number may be employed in the present invention.
  • intraocular lens 10 is implanted in eye 14 following cataract surgery resulting in capsular bag 26 shown in Figs. 1, 3, and 5.
  • Figs. 3-6 represent the dynamics of intraocular lens 10 within eye 14.
  • Fig. 3 shows the relaxing of zonules 32 causing the partial collapsing of capsular bag 26 according to directional arrows 66 and 68.
  • Such collapsing of capsular bag 26 forces optical element 12 anteriorly according to directional arrow 70.
  • sets of plurality of flexible arms 62 and 64 rotate counter clockwise when viewing optical element 12 from the left side of Fig. 3.
  • Elongated members 44 and 46 do not move since Chey are" ' fixed "" to ' capsular bag 26 by fibrous growth.
  • lens or optical element 12 also rotates slightly according to directional arrows 72 and 74.
  • Fig. 5 illustrates the opposite movement of optical element 12 where plurality of zonules have tensioned causing capsular bag to stretch according to directional arrows 76 and 78.
  • Capsular bag exerts a pulling force on flexible arm sets 62 and 64 moving optical element 12 posteriorly according to directional arrow 80.
  • Fig. 6 illustrates the clockwise turning of optical element 12 according to directional arrows 82 and 84 when optical element is viewed in the same manner as that depicted in Fig. 4.

Landscapes

  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Prostheses (AREA)

Abstract

L’invention concerne une lentille intraoculaire d’accommodation qui utilise un élément optique pour corriger la vision d'un patient. L'élément optique est placé dans le sac capsulaire ouvert après une intervention chirurgicale extracapsulaire et une phakoémulsification de la lentille naturelle brouillée. L'élément optique est ajusté antérieurement et postérieurement par une pluralité de bras qui sont reliés au sac capsulaire ouvert retenu par le système lamellaire de l'oeil.
PCT/US2006/000370 2006-01-09 2006-01-09 Lentille intraoculaire d’accommodation WO2007081311A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/US2006/000370 WO2007081311A1 (fr) 2006-01-09 2006-01-09 Lentille intraoculaire d’accommodation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2006/000370 WO2007081311A1 (fr) 2006-01-09 2006-01-09 Lentille intraoculaire d’accommodation

Publications (1)

Publication Number Publication Date
WO2007081311A1 true WO2007081311A1 (fr) 2007-07-19

Family

ID=38256610

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/000370 WO2007081311A1 (fr) 2006-01-09 2006-01-09 Lentille intraoculaire d’accommodation

Country Status (1)

Country Link
WO (1) WO2007081311A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114041900A (zh) * 2021-11-18 2022-02-15 郑州耐视医药科技有限公司 一种精确调整焦距的基本晶状体结构

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6013101A (en) * 1994-11-21 2000-01-11 Acuity (Israel) Limited Accommodating intraocular lens implant
US6261321B1 (en) * 1999-09-01 2001-07-17 Robert E. Kellan Phakic or aphakic intraocular lens assembly

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6013101A (en) * 1994-11-21 2000-01-11 Acuity (Israel) Limited Accommodating intraocular lens implant
US6261321B1 (en) * 1999-09-01 2001-07-17 Robert E. Kellan Phakic or aphakic intraocular lens assembly

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114041900A (zh) * 2021-11-18 2022-02-15 郑州耐视医药科技有限公司 一种精确调整焦距的基本晶状体结构

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