WO2007079558A3 - Proline-rich peptides, pharmaceutical composition, use of one or more peptides and method of treatment - Google Patents

Proline-rich peptides, pharmaceutical composition, use of one or more peptides and method of treatment Download PDF

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Publication number
WO2007079558A3
WO2007079558A3 PCT/BR2007/000003 BR2007000003W WO2007079558A3 WO 2007079558 A3 WO2007079558 A3 WO 2007079558A3 BR 2007000003 W BR2007000003 W BR 2007000003W WO 2007079558 A3 WO2007079558 A3 WO 2007079558A3
Authority
WO
WIPO (PCT)
Prior art keywords
peptides
proline
treatment
pharmaceutical composition
present
Prior art date
Application number
PCT/BR2007/000003
Other languages
French (fr)
Other versions
WO2007079558B1 (en
WO2007079558A2 (en
Inventor
Antonio Camargo
Danielle Ianzer
Carlos Silva
Claudiana Gomes
Juliano Guerreiro
Original Assignee
Pep Farma Consultoria E Desenv
Antonio Camargo
Danielle Ianzer
Carlos Silva
Claudiana Gomes
Juliano Guerreiro
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pep Farma Consultoria E Desenv, Antonio Camargo, Danielle Ianzer, Carlos Silva, Claudiana Gomes, Juliano Guerreiro filed Critical Pep Farma Consultoria E Desenv
Priority to EP07700096A priority Critical patent/EP1979373A2/en
Priority to US11/813,346 priority patent/US20100035822A1/en
Priority to JP2008548908A priority patent/JP2009522314A/en
Publication of WO2007079558A2 publication Critical patent/WO2007079558A2/en
Publication of WO2007079558A3 publication Critical patent/WO2007079558A3/en
Publication of WO2007079558B1 publication Critical patent/WO2007079558B1/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The present invention provides oligopeptides with amino acid sequences comprised in set forth in SEQ ID NO 1 to 18, capable of binding to diverse targets, generating increase and sustenance to nitric oxide (NO) production in mammalian cells, potentiate the argininosuccinate synthase activity of animal cells and/or increase the intracellular bivalent calcium ion in animal cells. Also disclosed are pharmaceutical compositions of one or more peptides described in the present invention. The invention further relates to the use of these peptides.
PCT/BR2007/000003 2006-01-09 2007-01-05 Proline-rich peptides, pharmaceutical composition, use of one or more peptides and method of treatment WO2007079558A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP07700096A EP1979373A2 (en) 2006-01-09 2007-01-05 Proline-rich peptides, pharmaceutical composition, use of one or more peptides and method of treatment
US11/813,346 US20100035822A1 (en) 2006-01-09 2007-01-05 Proline-rich peptides, pharmaceutical composition, use of one or more peptides and method of treatment
JP2008548908A JP2009522314A (en) 2006-01-09 2007-01-05 Proline-rich peptides, pharmaceutical compositions, uses of one or more peptides and methods of treatment

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
BRPI0600331 2006-01-09
BRPI0600331-1 2006-01-09
BRPI0607366-2 2006-12-26

Publications (3)

Publication Number Publication Date
WO2007079558A2 WO2007079558A2 (en) 2007-07-19
WO2007079558A3 true WO2007079558A3 (en) 2007-08-30
WO2007079558B1 WO2007079558B1 (en) 2007-10-04

Family

ID=38256648

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/BR2007/000003 WO2007079558A2 (en) 2006-01-09 2007-01-05 Proline-rich peptides, pharmaceutical composition, use of one or more peptides and method of treatment

Country Status (1)

Country Link
WO (1) WO2007079558A2 (en)

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
CINTRA A.C., VIEIRA C.A., GIGLIO J.R.: "Primary structure and biological activity of bradykinin potentiating peptides from Bothrops insularis snake venom", J. PROTEIN CHEM., vol. 9, no. 2, April 1990 (1990-04-01), pages 221 - 227, XP008107868 *
IANZER D. ET AL.: "Identification of five new bradykinin potentiating peptides (BPPs) from bothrops jararaca crude venom by using electrospray ionization tandem mass spectrometry after af two-step liquid chromatography", PEPTIDES, vol. 25, no. 7, July 2004 (2004-07-01), pages 1085 - 1092, XP003024773 *
ONDETTI M.A. ET AL.: "Angiotensin-converting enzyme inhibitors from the venom of Bothrops jararaca, Isolation, elucidation of structure, and synthesis", BIOCHEMISTRY, vol. 10, no. 22, 26 October 1971 (1971-10-26), pages 4033 - 4039, XP003024772 *
POLITI V. ET AL.: "A new peptide from Crotalus snake venom", PEPTIDES, no. 3, SUPPL. 6, 1985, pages 343 - 346, XP023486284 *

Also Published As

Publication number Publication date
WO2007079558B1 (en) 2007-10-04
WO2007079558A2 (en) 2007-07-19

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