WO2007075899A8 - Composes agonistes doubles et leur utilisation - Google Patents

Composes agonistes doubles et leur utilisation

Info

Publication number
WO2007075899A8
WO2007075899A8 PCT/US2006/048807 US2006048807W WO2007075899A8 WO 2007075899 A8 WO2007075899 A8 WO 2007075899A8 US 2006048807 W US2006048807 W US 2006048807W WO 2007075899 A8 WO2007075899 A8 WO 2007075899A8
Authority
WO
WIPO (PCT)
Prior art keywords
dual agonist
agonist compounds
provides
compounds
human
Prior art date
Application number
PCT/US2006/048807
Other languages
English (en)
Other versions
WO2007075899A2 (fr
WO2007075899A3 (fr
Inventor
Stephen F Parmley
Madan M Paidhungat
Stephanie J Lathrop
Sarah Patrick
Claus M Krebber
Aaron Kurtzman
Margaret Neighbors
Kim V Andersen
Steven H Bass
Sridhar Viswanathan
Original Assignee
Maxygen Inc
Stephen F Parmley
Madan M Paidhungat
Stephanie J Lathrop
Sarah Patrick
Claus M Krebber
Aaron Kurtzman
Margaret Neighbors
Kim V Andersen
Steven H Bass
Sridhar Viswanathan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Maxygen Inc, Stephen F Parmley, Madan M Paidhungat, Stephanie J Lathrop, Sarah Patrick, Claus M Krebber, Aaron Kurtzman, Margaret Neighbors, Kim V Andersen, Steven H Bass, Sridhar Viswanathan filed Critical Maxygen Inc
Publication of WO2007075899A2 publication Critical patent/WO2007075899A2/fr
Publication of WO2007075899A8 publication Critical patent/WO2007075899A8/fr
Publication of WO2007075899A3 publication Critical patent/WO2007075899A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/524—Thrombopoietin, i.e. C-MPL ligand
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5403—IL-3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7158—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for chemokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La présente invention concerne des composés agonistes doubles qui présentent une activité agoniste par rapport au récepteur humain de la thrombopoïétine c-Mpl et au récepteur humain IL-3. L’invention se rapporte à des composés agonistes doubles qui comprennent des polypeptides agonistes doubles, ainsi qu’à des acides nucléiques, des conjugués, des vecteurs, des cellules et des procédés correspondants destinés à la production et à l’utilisation de ces composés agonistes doubles.
PCT/US2006/048807 2005-12-21 2006-12-20 Composes agonistes doubles et leur utilisation WO2007075899A2 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US75292405P 2005-12-21 2005-12-21
US60/752,924 2005-12-21
US83108706P 2006-07-14 2006-07-14
US60/831,087 2006-07-14

Publications (3)

Publication Number Publication Date
WO2007075899A2 WO2007075899A2 (fr) 2007-07-05
WO2007075899A8 true WO2007075899A8 (fr) 2007-11-01
WO2007075899A3 WO2007075899A3 (fr) 2008-06-05

Family

ID=38218617

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/048807 WO2007075899A2 (fr) 2005-12-21 2006-12-20 Composes agonistes doubles et leur utilisation

Country Status (1)

Country Link
WO (1) WO2007075899A2 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2443139B1 (fr) 2009-06-16 2016-08-10 Codexis, Inc. Enzymes variantes de la bêta-glucosidase et polynucléotides apparentés
WO2010148148A2 (fr) 2009-06-16 2010-12-23 Codexis, Inc. Variants de β-glucosidase
CN102666848B (zh) 2009-11-25 2014-09-24 科德克希思公司 用于从纤维素生物质产生可发酵的糖的重组嗜热子囊菌β-葡糖苷酶变体
MX2012006016A (es) 2009-11-25 2012-06-25 Codexis Inc Variantes de beta-glucosidasa recombinante para produccion de azucares solubles de biomasa celulosica.
EP2794871A4 (fr) 2011-12-20 2015-12-30 Codexis Inc Variantes d'endoglucanases 1b (eg1b)
CN108264547B (zh) * 2016-12-30 2021-09-21 四川科伦博泰生物医药股份有限公司 一种纯化蛋白的方法以及试剂盒
PE20211902A1 (es) * 2019-03-01 2021-09-27 Allogene Therapeutics Inc Receptores de citocinas quimericos constitutivamente activos
MX2021010444A (es) 2019-03-01 2021-09-21 Allogene Therapeutics Inc Receptores de citocinas quimericos que tienen un ectodominio de pd-1.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL123832A0 (en) * 1995-10-05 1998-10-30 Searle & Co Multi-functional hematopoietic receptor antagonists
AU773891C (en) * 1998-10-23 2005-02-17 Kirin-Amgen Inc. Dimeric thrombopoietin peptide mimetics binding to MP1 receptor and having thrombopoietic activity

Also Published As

Publication number Publication date
WO2007075899A2 (fr) 2007-07-05
WO2007075899A3 (fr) 2008-06-05

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