WO2007069157A3 - Method and apparatus for guidance and application of high intensity focused ultrasound for control of bleeding due to severed limbs - Google Patents

Method and apparatus for guidance and application of high intensity focused ultrasound for control of bleeding due to severed limbs Download PDF

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Publication number
WO2007069157A3
WO2007069157A3 PCT/IB2006/054673 IB2006054673W WO2007069157A3 WO 2007069157 A3 WO2007069157 A3 WO 2007069157A3 IB 2006054673 W IB2006054673 W IB 2006054673W WO 2007069157 A3 WO2007069157 A3 WO 2007069157A3
Authority
WO
WIPO (PCT)
Prior art keywords
severed
transducer
focused ultrasound
blood
hifu
Prior art date
Application number
PCT/IB2006/054673
Other languages
French (fr)
Other versions
WO2007069157A2 (en
Inventor
Helen Routh
John Fraser
John Petruzzello
Shervin Ayati
Original Assignee
Koninkl Philips Electronics Nv
Helen Routh
John Fraser
John Petruzzello
Shervin Ayati
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninkl Philips Electronics Nv, Helen Routh, John Fraser, John Petruzzello, Shervin Ayati filed Critical Koninkl Philips Electronics Nv
Priority to EP06832155A priority Critical patent/EP1962691A2/en
Priority to US12/096,716 priority patent/US8353834B2/en
Priority to JP2008545189A priority patent/JP2009525061A/en
Publication of WO2007069157A2 publication Critical patent/WO2007069157A2/en
Publication of WO2007069157A3 publication Critical patent/WO2007069157A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/42Details of probe positioning or probe attachment to the patient
    • A61B8/4209Details of probe positioning or probe attachment to the patient by using holders, e.g. positioning frames
    • A61B8/4227Details of probe positioning or probe attachment to the patient by using holders, e.g. positioning frames characterised by straps, belts, cuffs or braces
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/06Measuring blood flow
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/42Details of probe positioning or probe attachment to the patient
    • A61B8/4272Details of probe positioning or probe attachment to the patient involving the acoustic interface between the transducer and the tissue
    • A61B8/4281Details of probe positioning or probe attachment to the patient involving the acoustic interface between the transducer and the tissue characterised by sound-transmitting media or devices for coupling the transducer to the tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/44Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
    • A61B8/4483Constructional features of the ultrasonic, sonic or infrasonic diagnostic device characterised by features of the ultrasound transducer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00Ultrasound therapy
    • A61N7/02Localised ultrasound hyperthermia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00Ultrasound therapy
    • A61N2007/0056Beam shaping elements
    • A61N2007/0065Concave transducers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00Ultrasound therapy
    • A61N2007/0078Ultrasound therapy with multiple treatment transducers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00Ultrasound therapy
    • A61N2007/0086Beam steering
    • A61N2007/0095Beam steering by modifying an excitation signal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00Ultrasound therapy
    • A61N7/02Localised ultrasound hyperthermia
    • A61N2007/027Localised ultrasound hyperthermia with multiple foci created simultaneously

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Acoustics & Sound (AREA)
  • Hematology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Thermotherapy And Cooling Therapy Devices (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Surgical Instruments (AREA)

Abstract

An ultrasonic diagnostic and therapy system is described for stopping the bleeding of severely damaged blood vessels or vessels severed in a limb amputation. A cuff is attached to the stump of the severed limb which contains a diagnostic transducer array and a HIFU transducer. The diagnostic transducer surveys the tissue of the severed limb, searching for a Doppler flow signal. When a Doppler flow signal is detected, the flow velocity and range and coordinates of the sample volume are determined. This information is supplied to a HIFU therapy transducer controller, which controls the HIFU transducer to transmit focused ultrasound to the sample volume of the flow locus. The focused ultrasound heats and coagulates blood in the severed vessel to stem the bleeding. Heat dissipation is reduced by tracking and continuously heating the same bolus of blood as it flows, or by heating a significant length of the blood vessel.
PCT/IB2006/054673 2005-12-14 2006-12-07 Method and apparatus for guidance and application of high intensity focused ultrasound for control of bleeding due to severed limbs WO2007069157A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP06832155A EP1962691A2 (en) 2005-12-14 2006-12-07 Method and apparatus for guidance and application of high intensity focused ultrasound for control of bleeding due to severed limbs
US12/096,716 US8353834B2 (en) 2005-12-14 2006-12-07 Method and apparatus for guidance and application of high intensity focused ultrasound for control of bleeding due to severed limbs
JP2008545189A JP2009525061A (en) 2005-12-14 2006-12-07 Method and apparatus for guidance and application of high intensity focused ultrasound for controlling bleeding due to amputated limbs

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75064805P 2005-12-14 2005-12-14
US60/750,648 2005-12-14

Publications (2)

Publication Number Publication Date
WO2007069157A2 WO2007069157A2 (en) 2007-06-21
WO2007069157A3 true WO2007069157A3 (en) 2009-04-16

Family

ID=38163308

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2006/054673 WO2007069157A2 (en) 2005-12-14 2006-12-07 Method and apparatus for guidance and application of high intensity focused ultrasound for control of bleeding due to severed limbs

Country Status (4)

Country Link
US (1) US8353834B2 (en)
EP (1) EP1962691A2 (en)
JP (1) JP2009525061A (en)
WO (1) WO2007069157A2 (en)

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US6618620B1 (en) 2000-11-28 2003-09-09 Txsonics Ltd. Apparatus for controlling thermal dosing in an thermal treatment system
US8409099B2 (en) * 2004-08-26 2013-04-02 Insightec Ltd. Focused ultrasound system for surrounding a body tissue mass and treatment method
US8750983B2 (en) 2004-09-20 2014-06-10 P Tech, Llc Therapeutic system
US8608672B2 (en) 2005-11-23 2013-12-17 Insightec Ltd. Hierarchical switching in ultra-high density ultrasound array
US7920731B2 (en) * 2007-03-27 2011-04-05 Siemens Medical Solutions Usa, Inc. Bleeding detection using a blanket ultrasound device
US8251908B2 (en) 2007-10-01 2012-08-28 Insightec Ltd. Motion compensated image-guided focused ultrasound therapy system
WO2010017396A2 (en) * 2008-08-07 2010-02-11 University Of Rochester Medical Center Robotic localizing aid for high intensity focused ultrasound delivery
US8425424B2 (en) 2008-11-19 2013-04-23 Inightee Ltd. Closed-loop clot lysis
US8617073B2 (en) 2009-04-17 2013-12-31 Insightec Ltd. Focusing ultrasound into the brain through the skull by utilizing both longitudinal and shear waves
US9623266B2 (en) 2009-08-04 2017-04-18 Insightec Ltd. Estimation of alignment parameters in magnetic-resonance-guided ultrasound focusing
WO2011024074A2 (en) 2009-08-26 2011-03-03 Insightec Ltd. Asymmetric phased-array ultrasound transducer
US8986211B2 (en) * 2009-10-12 2015-03-24 Kona Medical, Inc. Energetic modulation of nerves
US9119951B2 (en) 2009-10-12 2015-09-01 Kona Medical, Inc. Energetic modulation of nerves
US20160059044A1 (en) 2009-10-12 2016-03-03 Kona Medical, Inc. Energy delivery to intraparenchymal regions of the kidney to treat hypertension
US11998266B2 (en) 2009-10-12 2024-06-04 Otsuka Medical Devices Co., Ltd Intravascular energy delivery
US8469904B2 (en) * 2009-10-12 2013-06-25 Kona Medical, Inc. Energetic modulation of nerves
US8986231B2 (en) 2009-10-12 2015-03-24 Kona Medical, Inc. Energetic modulation of nerves
US20110118600A1 (en) * 2009-11-16 2011-05-19 Michael Gertner External Autonomic Modulation
US8517962B2 (en) * 2009-10-12 2013-08-27 Kona Medical, Inc. Energetic modulation of nerves
US20110092880A1 (en) 2009-10-12 2011-04-21 Michael Gertner Energetic modulation of nerves
US9174065B2 (en) * 2009-10-12 2015-11-03 Kona Medical, Inc. Energetic modulation of nerves
US8295912B2 (en) 2009-10-12 2012-10-23 Kona Medical, Inc. Method and system to inhibit a function of a nerve traveling with an artery
US8661873B2 (en) 2009-10-14 2014-03-04 Insightec Ltd. Mapping ultrasound transducers
US8932237B2 (en) 2010-04-28 2015-01-13 Insightec, Ltd. Efficient ultrasound focusing
US9852727B2 (en) 2010-04-28 2017-12-26 Insightec, Ltd. Multi-segment ultrasound transducers
EP2386248B1 (en) 2010-05-14 2018-06-27 Samsung Medison Co., Ltd. Ultrasonic diagnostic apparatus
US9981148B2 (en) 2010-10-22 2018-05-29 Insightec, Ltd. Adaptive active cooling during focused ultrasound treatment
US8968205B2 (en) 2011-02-10 2015-03-03 Siemens Medical Solutions Usa, Inc. Sub-aperture control in high intensity focused ultrasound
US10130374B2 (en) 2012-05-11 2018-11-20 Michael Zhadkevich Anti-embolic device and method
US9463026B2 (en) 2012-11-21 2016-10-11 Medical Ingenuities, LLC Radial compression hemostasis band with Doppler confirming vascular patency
US10925579B2 (en) 2014-11-05 2021-02-23 Otsuka Medical Devices Co., Ltd. Systems and methods for real-time tracking of a target tissue using imaging before and during therapy delivery
EP3050520A1 (en) 2015-01-27 2016-08-03 Michael Zhadkevich Devices and techniques for vascular compression
EP3302304A4 (en) 2015-06-08 2019-02-27 Richard F. Corrigan Jr. Radial compression hemostasis band with doppler confirming vascular patency
JP7076210B2 (en) 2015-06-30 2022-05-27 コーニンクレッカ フィリップス エヌ ヴェ Methods, devices and systems for coupling flexible transducers to surfaces
US11103416B2 (en) * 2015-09-28 2021-08-31 Michael Zhadkevich Device and method for simultaneous detection, monitoring and prevention of cerebral emboli
US11583188B2 (en) 2019-03-18 2023-02-21 General Electric Company Automated detection and localization of bleeding
US20210236858A1 (en) * 2020-02-04 2021-08-05 General Electric Company Automated ultrasound bleeding detection and treatment
US11457889B2 (en) * 2021-01-25 2022-10-04 Lazaro Eduardo Hernandez System and method of non-invasive continuous echocardiographic monitoring
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Also Published As

Publication number Publication date
US20080312562A1 (en) 2008-12-18
US8353834B2 (en) 2013-01-15
JP2009525061A (en) 2009-07-09
EP1962691A2 (en) 2008-09-03
WO2007069157A2 (en) 2007-06-21

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