WO2007066131A3 - A method of detecting skeletal muscle damage - Google Patents

A method of detecting skeletal muscle damage Download PDF

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Publication number
WO2007066131A3
WO2007066131A3 PCT/GB2006/004598 GB2006004598W WO2007066131A3 WO 2007066131 A3 WO2007066131 A3 WO 2007066131A3 GB 2006004598 W GB2006004598 W GB 2006004598W WO 2007066131 A3 WO2007066131 A3 WO 2007066131A3
Authority
WO
WIPO (PCT)
Prior art keywords
skeletal muscle
muscle damage
detecting skeletal
detecting
damage
Prior art date
Application number
PCT/GB2006/004598
Other languages
French (fr)
Other versions
WO2007066131A2 (en
Inventor
Julie Christine Barnes
Paul Michael Bradley
Original Assignee
Biowisdom Ltd
Julie Christine Barnes
Paul Michael Bradley
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biowisdom Ltd, Julie Christine Barnes, Paul Michael Bradley filed Critical Biowisdom Ltd
Publication of WO2007066131A2 publication Critical patent/WO2007066131A2/en
Publication of WO2007066131A3 publication Critical patent/WO2007066131A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/10—Musculoskeletal or connective tissue disorders

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The present invention relates to a method of detecting skeletal muscle damage and to the use of certain proteins and fragments thereof as biological markers (commonly known as 'biomarkers') for such damage. The present invention has particular reference to the detection of muscle toxicity in mammals, particularly humans.
PCT/GB2006/004598 2005-12-08 2006-12-08 A method of detecting skeletal muscle damage WO2007066131A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0525048.5 2005-12-08
GB0525048A GB0525048D0 (en) 2005-12-08 2005-12-08 A method of detecting skeletal muscle damage

Publications (2)

Publication Number Publication Date
WO2007066131A2 WO2007066131A2 (en) 2007-06-14
WO2007066131A3 true WO2007066131A3 (en) 2007-11-01

Family

ID=35735782

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2006/004598 WO2007066131A2 (en) 2005-12-08 2006-12-08 A method of detecting skeletal muscle damage

Country Status (2)

Country Link
GB (1) GB0525048D0 (en)
WO (1) WO2007066131A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009078806A2 (en) * 2007-12-19 2009-06-25 Bror Christer Malm Skeletal muscle proteome, muscle function and physical performance
BR102021020613A2 (en) * 2021-10-14 2023-04-18 Universidade Federal Do Rio De Janeiro PROTEOMY INVESTIGATION METHOD IN SAMPLE FOR DIAGNOSIS OF RABDOMYOLYSIS AND KITS FOR PERFORMING THE SAME

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DARE THEO O ET AL: "Application of surface-enhanced laser desorption/ionization technology to the detection and identification of urinary parvalbumin-alpha: A biomarker of compound-induced skeletal muscle toxicity in the rat.", ELECTROPHORESIS, vol. 23, no. 18, September 2002 (2002-09-01), pages 3241 - 3251, XP002423409, ISSN: 0173-0835 *
LECHNER C ET AL: "ERK6, A MITOGEN-ACTIVATED PROTEIN KINASE INVOLVED IN C2C12 MYOBLASTDIFFERENTIATION", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, US, vol. 93, April 1996 (1996-04-01), pages 4355 - 4359, XP002053846, ISSN: 0027-8424 *
SORICHTER STEPHAN ET AL: "Skeletal troponin I as a marker of exercise-induced muscle damage", JOURNAL OF APPLIED PHYSIOLOGY, vol. 83, no. 4, 1997, pages 1076 - 1082, XP002423408, ISSN: 8750-7587 *

Also Published As

Publication number Publication date
WO2007066131A2 (en) 2007-06-14
GB0525048D0 (en) 2006-01-18

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