WO2007056049A3 - Profilage moleculaire de cancer - Google Patents
Profilage moleculaire de cancer Download PDFInfo
- Publication number
- WO2007056049A3 WO2007056049A3 PCT/US2006/042784 US2006042784W WO2007056049A3 WO 2007056049 A3 WO2007056049 A3 WO 2007056049A3 US 2006042784 W US2006042784 W US 2006042784W WO 2007056049 A3 WO2007056049 A3 WO 2007056049A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- cancer
- molecular profiling
- present
- cancer markers
- prostate
- Prior art date
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57434—Specifically defined cancers of prostate
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57415—Specifically defined cancers of breast
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Pathology (AREA)
- Biomedical Technology (AREA)
- Analytical Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
La présente invention concerne des compositions et des procédés pour le diagnostic du cancer, comprenant sans y être limités, des marqueurs de cancer, en particulier, la présente invention concerne des marqueurs de cancer utiles dans le diagnostic et la caractérisation de cancers de la prostate et du sein.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP06836805A EP1945817A4 (fr) | 2005-11-02 | 2006-11-02 | Profilage moleculaire de cancer |
CA002628390A CA2628390A1 (fr) | 2005-11-02 | 2006-11-02 | Profilage moleculaire de cancer |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US73285905P | 2005-11-02 | 2005-11-02 | |
US60/732,859 | 2005-11-02 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2007056049A2 WO2007056049A2 (fr) | 2007-05-18 |
WO2007056049A3 true WO2007056049A3 (fr) | 2008-01-31 |
Family
ID=38023798
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2006/042784 WO2007056049A2 (fr) | 2005-11-02 | 2006-11-02 | Profilage moleculaire de cancer |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP1945817A4 (fr) |
CA (1) | CA2628390A1 (fr) |
WO (1) | WO2007056049A2 (fr) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008039774A1 (fr) | 2006-09-25 | 2008-04-03 | Mayo Foundation For Medical Education And Research | Marqueurs associés à une membrane et marqueurs extracellulaires du cancer de la prostate |
US8338109B2 (en) | 2006-11-02 | 2012-12-25 | Mayo Foundation For Medical Education And Research | Predicting cancer outcome |
AU2009253675A1 (en) | 2008-05-28 | 2009-12-03 | Genomedx Biosciences, Inc. | Systems and methods for expression-based discrimination of distinct clinical disease states in prostate cancer |
US10407731B2 (en) | 2008-05-30 | 2019-09-10 | Mayo Foundation For Medical Education And Research | Biomarker panels for predicting prostate cancer outcomes |
JP2012504397A (ja) * | 2008-10-01 | 2012-02-23 | ノヴィオジェンディクス・リサーチ・ベスローテン・フェンノートシャップ | 前立腺がんにおける分子マーカー |
EP2243843A1 (fr) * | 2009-04-24 | 2010-10-27 | Institut Curie | HP1ALPHA en tant que marqueur de pronostic dans le cancer humain |
CA2858581A1 (fr) | 2011-12-13 | 2013-06-20 | Genomedx Biosciences, Inc. | Diagnostics du cancer a l'aide de transcriptions non codantes |
WO2014028884A2 (fr) * | 2012-08-16 | 2014-02-20 | Genomedx Biosciences, Inc. | Diagnostic du cancer au moyen de biomarqueurs |
EP3504348B1 (fr) | 2016-08-24 | 2022-12-14 | Decipher Biosciences, Inc. | Utilisation de signatures génomiques en vue d'une prédiction de la réactivité de patients atteints d'un cancer de la prostate à une radiothérapie postopératoire |
US11208697B2 (en) | 2017-01-20 | 2021-12-28 | Decipher Biosciences, Inc. | Molecular subtyping, prognosis, and treatment of bladder cancer |
CA3055925A1 (fr) | 2017-03-09 | 2018-09-13 | Decipher Biosciences, Inc. | Sous-typage du cancer de la prostate pour predire la reponse a une therapie hormonale |
JP7278595B2 (ja) * | 2017-03-16 | 2023-05-22 | ユニベルシテ リブレ デ ブリュッセル | Cd321マーカーの発現に基づく循環腫瘍細胞の検出、定量化、及び/又は単離 |
WO2018205035A1 (fr) | 2017-05-12 | 2018-11-15 | Genomedx Biosciences, Inc | Signatures génétiques pour prédire une métastase du cancer de la prostate et identifier la virulence d'une tumeur |
CN115436636A (zh) * | 2022-11-08 | 2022-12-06 | 济南市中心医院 | 连接粘附分子样蛋白jaml在结直肠癌中的应用 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020086406A1 (en) * | 1998-04-09 | 2002-07-04 | Incyte Pharmaceuticals, Inc. | Human ubiquitin-conjugating enzyme homologs |
WO2002061081A1 (fr) * | 2001-01-31 | 2002-08-08 | Bionomics Limited | Une nouvelle cartographie du gene bn01 au chromosome 16q24.3 |
WO2003088910A2 (fr) * | 2002-04-15 | 2003-10-30 | Rigel Pharmaceuticals, Inc. | Procedes de criblage de modulateurs du cycle cellulaire |
WO2005047321A2 (fr) * | 2003-11-14 | 2005-05-26 | Creighton University | Polynucléotides inhibant l'expression de polypeptides et leurs méthodes d'utilisation |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6949342B2 (en) * | 2001-12-21 | 2005-09-27 | Whitehead Institute For Biomedical Research | Prostate cancer diagnosis and outcome prediction by expression analysis |
-
2006
- 2006-11-02 WO PCT/US2006/042784 patent/WO2007056049A2/fr active Application Filing
- 2006-11-02 EP EP06836805A patent/EP1945817A4/fr not_active Withdrawn
- 2006-11-02 CA CA002628390A patent/CA2628390A1/fr not_active Abandoned
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020086406A1 (en) * | 1998-04-09 | 2002-07-04 | Incyte Pharmaceuticals, Inc. | Human ubiquitin-conjugating enzyme homologs |
WO2002061081A1 (fr) * | 2001-01-31 | 2002-08-08 | Bionomics Limited | Une nouvelle cartographie du gene bn01 au chromosome 16q24.3 |
WO2003088910A2 (fr) * | 2002-04-15 | 2003-10-30 | Rigel Pharmaceuticals, Inc. | Procedes de criblage de modulateurs du cycle cellulaire |
WO2005047321A2 (fr) * | 2003-11-14 | 2005-05-26 | Creighton University | Polynucléotides inhibant l'expression de polypeptides et leurs méthodes d'utilisation |
Non-Patent Citations (6)
Title |
---|
BEN-IZHAK O. ET AL.: "Inverse Relationship Between SKP2 Ubiquitin Ligase and The Cyclin Dependent Kinase Inhibitor p27Kip1 In Prostate Cancer", THE JOURNAL OF UROLOGY, vol. 170, no. 1, July 2003 (2003-07-01), pages 241 - 245, XP005536043 * |
CARDOZO T. ET AL.: "The SCF ubiquitin ligase: insights into a molecular machine", NATURE REVIEWS MOLECULAR CELL BIOLOGY, vol. 5, no. 9, September 2004 (2004-09-01), pages 739 - 751, XP008127053 * |
LU L. ET AL.: "The F-box Protein SKP 2 Mediates Androgen Control of p27 Stability in LNCaP Human Prostate Cancer Cells", BMC CELL BIOLOGY, vol. 3, no. 22, 20 August 2002 (2002-08-20), XP021014065 * |
MYERS E.L. ET AL.: "Tsg101, an Inactive Homologue of Ubiquitin Ligase E2, Interacts Specifically with Human Immunodeficiency Virus Type 2 Gag Polyprotein and Results in Increased Levels of Ubiquitinated Gag", JOURNAL OF VIROLOGY, vol. 76, no. 22, November 2002 (2002-11-01), pages 11226 - 11235, XP002968048 * |
See also references of EP1945817A4 * |
STUBBS A.P. ET AL.: "Differentially Expressed Genes in Hormone Refractory Prostate Cancer", AMERICAN JOURNAL OF PATHOLOGY, vol. 154, no. 5, May 1999 (1999-05-01), pages 1335 - 1343, XP001176972 * |
Also Published As
Publication number | Publication date |
---|---|
EP1945817A4 (fr) | 2008-12-10 |
CA2628390A1 (fr) | 2007-05-18 |
EP1945817A2 (fr) | 2008-07-23 |
WO2007056049A2 (fr) | 2007-05-18 |
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