WO2007047576A1 - Traitements pharmacologiques contre des troubles du sommeil - Google Patents

Traitements pharmacologiques contre des troubles du sommeil Download PDF

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Publication number
WO2007047576A1
WO2007047576A1 PCT/US2006/040363 US2006040363W WO2007047576A1 WO 2007047576 A1 WO2007047576 A1 WO 2007047576A1 US 2006040363 W US2006040363 W US 2006040363W WO 2007047576 A1 WO2007047576 A1 WO 2007047576A1
Authority
WO
WIPO (PCT)
Prior art keywords
sleep
agents
antitussive
serotonin
apnea
Prior art date
Application number
PCT/US2006/040363
Other languages
English (en)
Inventor
David W. Carley
Miodrag Radulovaski
Original Assignee
The Board Of Trustees Of The University Of Illinois
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Board Of Trustees Of The University Of Illinois filed Critical The Board Of Trustees Of The University Of Illinois
Publication of WO2007047576A1 publication Critical patent/WO2007047576A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne des méthodes pour prévenir ou améliorer des troubles de la respiration associés au sommeil. La méthode consiste à administrer à un patient une dose efficace d'un ou de plusieurs agents antitussifs. L'agent antitussif ou la combinaison d'agents antitussifs peuvent être administrés en conjonction avec un ou plusieurs agonistes du récepteur de sérotonine, un ou plusieurs agonistes du récepteur cannabinoïde, un ou plusieurs inhibiteurs de recaptage de sérotonine, une combinaison d'inhibiteurs de recaptage, d'autres agents ou une combinaison quelconque de ces substances.
PCT/US2006/040363 2005-10-14 2006-10-13 Traitements pharmacologiques contre des troubles du sommeil WO2007047576A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72719205P 2005-10-14 2005-10-14
US60/727,192 2005-10-14

Publications (1)

Publication Number Publication Date
WO2007047576A1 true WO2007047576A1 (fr) 2007-04-26

Family

ID=37806724

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/040363 WO2007047576A1 (fr) 2005-10-14 2006-10-13 Traitements pharmacologiques contre des troubles du sommeil

Country Status (1)

Country Link
WO (1) WO2007047576A1 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008017753A2 (fr) * 2006-07-31 2008-02-14 Sanofi Aventis Composition pharmaceutique contenant en association le saredutant et un inhibiteur selectif de la recapture de la serotonine ou un inhibiteur de la recapture de la serotonine/norepinephrine
FR2912057A1 (fr) * 2007-02-07 2008-08-08 Sanofi Aventis Sa Composition pharmaceutique contenant en association le saredutant et un inhibiteur selectif de la recapture de la serotonine ou un inhibiteur de la recapture de la serotonine/norepinephrine
WO2013154347A1 (fr) * 2012-04-10 2013-10-17 Hanmi Pharm. Co., Ltd. Formulation liquide destinée à une administration orale comprenant de l'ambroxol, de la lévodropropizine et un agent tampon, et son procédé de préparation

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000051590A2 (fr) * 1999-03-04 2000-09-08 The Board Of Trustees Of The University Of Illinois Traitement neuropharmacologique des troubles de respiration lies au sommeil
WO2002080903A1 (fr) * 2001-04-06 2002-10-17 The Board Of Trustees Of The University Of Illinois Role fonctionnel des cannabinoides sur la stabilite autonome pendant le sommeil
US20030130266A1 (en) * 2001-12-14 2003-07-10 Miodrag Radulovacki Pharmacological treatment for sleep apnea
WO2005025621A1 (fr) * 2003-09-10 2005-03-24 Qrx Pharma Pty, Ltd. Procedes et compositions pour reduire le risque associe a l'administration d'analgesiques opioides chez des patients souffrant d'un trouble respiratoire diagnostique ou non diagnostique
WO2005027853A2 (fr) * 2003-09-19 2005-03-31 University Of Louisville Research Foundation Inc Methode de traitement du ronflement et de l'apnee du sommeil avec des antagonistes de la leucotriene
US20060130833A1 (en) * 2004-12-16 2006-06-22 Magdy Younes Treatment of obstructive sleep apnea

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000051590A2 (fr) * 1999-03-04 2000-09-08 The Board Of Trustees Of The University Of Illinois Traitement neuropharmacologique des troubles de respiration lies au sommeil
WO2002080903A1 (fr) * 2001-04-06 2002-10-17 The Board Of Trustees Of The University Of Illinois Role fonctionnel des cannabinoides sur la stabilite autonome pendant le sommeil
US20030130266A1 (en) * 2001-12-14 2003-07-10 Miodrag Radulovacki Pharmacological treatment for sleep apnea
WO2005025621A1 (fr) * 2003-09-10 2005-03-24 Qrx Pharma Pty, Ltd. Procedes et compositions pour reduire le risque associe a l'administration d'analgesiques opioides chez des patients souffrant d'un trouble respiratoire diagnostique ou non diagnostique
WO2005027853A2 (fr) * 2003-09-19 2005-03-31 University Of Louisville Research Foundation Inc Methode de traitement du ronflement et de l'apnee du sommeil avec des antagonistes de la leucotriene
US20060130833A1 (en) * 2004-12-16 2006-06-22 Magdy Younes Treatment of obstructive sleep apnea

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
SMITH IAN E ET AL: "Pharmacotherapies for obstructive sleep apnoea - Where are we now?", DRUGS, vol. 64, no. 13, 2004, pages 1385 - 1399, XP009080202, ISSN: 0012-6667 *
SZALLASI ARPAD ET AL: "Vanilloid receptor TRPV1 antagonists as the next generation of painkillers. Are we putting the cart before the horse?", JOURNAL OF MEDICINAL CHEMISTRY 20 MAY 2004, vol. 47, no. 11, 20 May 2004 (2004-05-20), pages 2717 - 2723, XP002400521, ISSN: 0022-2623 *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008017753A2 (fr) * 2006-07-31 2008-02-14 Sanofi Aventis Composition pharmaceutique contenant en association le saredutant et un inhibiteur selectif de la recapture de la serotonine ou un inhibiteur de la recapture de la serotonine/norepinephrine
WO2008017753A3 (fr) * 2006-07-31 2009-02-19 Sanofi Aventis Composition pharmaceutique contenant en association le saredutant et un inhibiteur selectif de la recapture de la serotonine ou un inhibiteur de la recapture de la serotonine/norepinephrine
FR2912057A1 (fr) * 2007-02-07 2008-08-08 Sanofi Aventis Sa Composition pharmaceutique contenant en association le saredutant et un inhibiteur selectif de la recapture de la serotonine ou un inhibiteur de la recapture de la serotonine/norepinephrine
WO2013154347A1 (fr) * 2012-04-10 2013-10-17 Hanmi Pharm. Co., Ltd. Formulation liquide destinée à une administration orale comprenant de l'ambroxol, de la lévodropropizine et un agent tampon, et son procédé de préparation
KR101915056B1 (ko) 2012-04-10 2018-11-07 한미약품 주식회사 암브록솔, 레보드로프로피진 및 완충제를 포함하는 경구용 액상 제제 및 이의 제조방법

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