WO2007047189A3 - Targeted biocides - Google Patents

Targeted biocides Download PDF

Info

Publication number
WO2007047189A3
WO2007047189A3 PCT/US2006/039361 US2006039361W WO2007047189A3 WO 2007047189 A3 WO2007047189 A3 WO 2007047189A3 US 2006039361 W US2006039361 W US 2006039361W WO 2007047189 A3 WO2007047189 A3 WO 2007047189A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
relates
present
biocide
fusion protein
Prior art date
Application number
PCT/US2006/039361
Other languages
French (fr)
Other versions
WO2007047189A2 (en
Inventor
Michael Imboden
Michael W Riggs
Deborah Schaefer
Original Assignee
Iogenetics Llc
Univ Arizona
Michael Imboden
Michael W Riggs
Deborah Schaefer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Iogenetics Llc, Univ Arizona, Michael Imboden, Michael W Riggs, Deborah Schaefer filed Critical Iogenetics Llc
Priority to AU2006303998A priority Critical patent/AU2006303998A1/en
Priority to CA002625580A priority patent/CA2625580A1/en
Priority to EP06825629A priority patent/EP1933874A4/en
Publication of WO2007047189A2 publication Critical patent/WO2007047189A2/en
Publication of WO2007047189A3 publication Critical patent/WO2007047189A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/14—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from fungi, algea or lichens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/20—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans from protozoa
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/12—Immunoglobulins specific features characterized by their source of isolation or production isolated from milk
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/55—Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

The present invention relates to retroviral constructs that encode novel monoclonal antibodies, novel fusion proteins, and chimeric monoclonal antibodies and to methods of using and producing the same. In particular, the present invention relates to methods of producing a fusion protein comprising a microorganism targeting molecule (e.g., immunoglobulin or innate immune system receptor molecule) and a biocide (e.g., bactericidal enzyme) in transgenic animals (e.g., bovines) and in cell cultures. The present invention also relates to therapeutic and prophylactic methods of using a fusion protein comprising a microorganism targeting molecule and a biocide in health care (e.g., human and veterinary), agriculture (e.g., animal and plant production), and food processing (e.g., beef carcass processing). The present invention also relates to methods of using a fusion protein comprising a microorganism targeting molecule and a biocide in various diagnostic applications in number of diverse fields such as agriculture, medicine, and national defense.
PCT/US2006/039361 2005-10-11 2006-10-10 Targeted biocides WO2007047189A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2006303998A AU2006303998A1 (en) 2005-10-11 2006-10-10 Targeted biocides
CA002625580A CA2625580A1 (en) 2005-10-11 2006-10-10 Targeted biocides
EP06825629A EP1933874A4 (en) 2005-10-11 2006-10-10 Targeted biocides

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72518005P 2005-10-11 2005-10-11
US60/725,180 2005-10-11

Publications (2)

Publication Number Publication Date
WO2007047189A2 WO2007047189A2 (en) 2007-04-26
WO2007047189A3 true WO2007047189A3 (en) 2007-11-15

Family

ID=37963026

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/039361 WO2007047189A2 (en) 2005-10-11 2006-10-10 Targeted biocides

Country Status (4)

Country Link
EP (1) EP1933874A4 (en)
AU (1) AU2006303998A1 (en)
CA (1) CA2625580A1 (en)
WO (1) WO2007047189A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8703134B2 (en) 2003-05-15 2014-04-22 Iogenetics, Llc Targeted cryptosporidium biocides
US8394379B2 (en) 2003-05-15 2013-03-12 Iogenetics, Llc Targeted cryptosporidium biocides
WO2012102679A1 (en) 2011-01-24 2012-08-02 National University Of Singapore Pathogenic mycobacteria-derived mannose-capped lipoarabinomannan antigen binding proteins
CN109942693B (en) * 2019-04-03 2020-12-25 周口师范学院 CTL epitope polypeptide of cryptosporidium parvum, application thereof and vaccine
CN113455394B (en) * 2021-07-23 2023-06-20 中国热带农业科学院橡胶研究所 Standardized production method for large-scale breeding of rubber tree body embryo seedlings

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040009167A1 (en) * 2002-02-07 2004-01-15 Massachusetts Institute Of Technology Anti-pathogen treatments
US20050014932A1 (en) * 2003-05-15 2005-01-20 Iogenetics, Llc Targeted biocides

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6015882A (en) * 1992-05-29 2000-01-18 The Regents Of The University Of California Vaccines, antibodies, proteins, glycoproteins, DNAs and RNAs for prophylaxis and treatment of Cryptosporidium parvum infections
EP0961547A4 (en) * 1996-08-23 2002-08-14 Univ North Carolina State Neutralization-sensitive epitopes of cryptosporidium parvum
AU2003298770A1 (en) * 2002-12-02 2004-06-23 Biosynexus Inc Wall teichoic acid as a target for anti-staphylococcal therapies and vaccines
US7718618B2 (en) * 2003-10-21 2010-05-18 The Regents Of The University Of California Human cathelicidin antimicrobial peptides
WO2006132665A2 (en) * 2004-10-20 2006-12-14 Iogenetics, Llc Biocides

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040009167A1 (en) * 2002-02-07 2004-01-15 Massachusetts Institute Of Technology Anti-pathogen treatments
US20050014932A1 (en) * 2003-05-15 2005-01-20 Iogenetics, Llc Targeted biocides

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
OREN ET AL.: "Structure and organization of the human antimicrobial peptide LL-37 in phospholipid membranes: relevance to the molecular basis for its non-cell-selective activity", BIOCHEM. J., vol. 341, no. PART 3, 1 August 1999 (1999-08-01), pages 501 - 513, XP001091195 *
PERRYMAN ET AL.: "Kinetics of Cryptosporidium parvum Sporozolla Neutrilization by Monoclonal Antibodies", INFECT. IMMUN., vol. 58, no. 1, January 1990 (1990-01-01), pages 257 - 259, XP000941233 *
See also references of EP1933874A4 *

Also Published As

Publication number Publication date
WO2007047189A2 (en) 2007-04-26
EP1933874A2 (en) 2008-06-25
AU2006303998A1 (en) 2007-04-26
CA2625580A1 (en) 2007-04-26
EP1933874A4 (en) 2010-03-03

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