WO2007035350A3 - Bioluminescence-based sensor with centrifugal separation and enhanced light collection - Google Patents

Bioluminescence-based sensor with centrifugal separation and enhanced light collection Download PDF

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Publication number
WO2007035350A3
WO2007035350A3 PCT/US2006/035639 US2006035639W WO2007035350A3 WO 2007035350 A3 WO2007035350 A3 WO 2007035350A3 US 2006035639 W US2006035639 W US 2006035639W WO 2007035350 A3 WO2007035350 A3 WO 2007035350A3
Authority
WO
WIPO (PCT)
Prior art keywords
bioluminescence
well
centrifugal separation
light collection
based sensor
Prior art date
Application number
PCT/US2006/035639
Other languages
French (fr)
Other versions
WO2007035350A2 (en
Inventor
Daniel A Bartholomeusz
Original Assignee
Univ Utah Res Found
Daniel A Bartholomeusz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Utah Res Found, Daniel A Bartholomeusz filed Critical Univ Utah Res Found
Priority to US12/067,002 priority Critical patent/US20090104643A1/en
Publication of WO2007035350A2 publication Critical patent/WO2007035350A2/en
Publication of WO2007035350A3 publication Critical patent/WO2007035350A3/en

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/76Chemiluminescence; Bioluminescence
    • G01N21/763Bioluminescence
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03Cuvette constructions
    • G01N21/07Centrifugal type cuvettes

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  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Engineering & Computer Science (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

In general, embodiments of the present invention relate to a bioluminescence-based point of care device that is made up of at least one reaction well (89)that contains a bioluminescent reagent for a luminescent reaction, sample well (80), sample collection well (84), and reagent well (87). A sample is introduced into the reaction wells (89), where it dissolves the reagents and initiates the luminescent reaction, where a luminescence signal is then transmitted through a window to a photo detector.
PCT/US2006/035639 2005-09-15 2006-09-13 Bioluminescence-based sensor with centrifugal separation and enhanced light collection WO2007035350A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US12/067,002 US20090104643A1 (en) 2005-09-15 2006-09-13 Bioluminescence-based sensor with centrifugal separation and enhanced light collection

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71779505P 2005-09-15 2005-09-15
US60/717,795 2005-09-15

Publications (2)

Publication Number Publication Date
WO2007035350A2 WO2007035350A2 (en) 2007-03-29
WO2007035350A3 true WO2007035350A3 (en) 2007-08-09

Family

ID=37889315

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/035639 WO2007035350A2 (en) 2005-09-15 2006-09-13 Bioluminescence-based sensor with centrifugal separation and enhanced light collection

Country Status (2)

Country Link
US (1) US20090104643A1 (en)
WO (1) WO2007035350A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20090079032A (en) * 2008-01-16 2009-07-21 삼성전자주식회사 Method of loading reagent into microfluidic device for blood biochemistry analysis
SG10201502531SA (en) * 2009-10-19 2015-05-28 Theranos Inc Integrated Health Data Capture And Analysis System
WO2012011074A2 (en) 2010-07-22 2012-01-26 Hach Company Lab-on-a-chip for alkalinity analysis
US9547014B2 (en) 2011-06-10 2017-01-17 Cornell University Immobilized protein system for rapid and enhanced multiplexed diagnostics
US9180449B2 (en) 2012-06-12 2015-11-10 Hach Company Mobile water analysis
USD768872S1 (en) 2012-12-12 2016-10-11 Hach Company Cuvette for a water analysis instrument
WO2017066485A1 (en) 2015-10-13 2017-04-20 Landers James P Devices and methods for extraction, separation and thermocycling
TWI777177B (en) * 2020-06-16 2022-09-11 逢甲大學 Centrifugal-driven microfluidic platform and method of use thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6319469B1 (en) * 1995-12-18 2001-11-20 Silicon Valley Bank Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system
US6720187B2 (en) * 2000-06-28 2004-04-13 3M Innovative Properties Company Multi-format sample processing devices

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6709869B2 (en) * 1995-12-18 2004-03-23 Tecan Trading Ag Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system
WO1998028623A1 (en) * 1996-12-20 1998-07-02 Gamera Bioscience Corporation An affinity binding-based system for detecting particulates in a fluid
US6706519B1 (en) * 1999-06-22 2004-03-16 Tecan Trading Ag Devices and methods for the performance of miniaturized in vitro amplification assays
DE60124699T2 (en) * 2000-05-15 2007-09-13 Tecan Trading Ag TWO DIRECTION FLOW ZENTRIFUGALMIKROFLUID DEVICES
US6734401B2 (en) * 2000-06-28 2004-05-11 3M Innovative Properties Company Enhanced sample processing devices, systems and methods
CA2441206A1 (en) * 2001-03-19 2002-09-26 Gyros Ab Characterization of reaction variables
SE0104077D0 (en) * 2001-10-21 2001-12-05 Gyros Ab A method and instrumentation for micro dispensation of droplets
SE0103109D0 (en) * 2001-09-17 2001-09-17 Gyros Microlabs Ab Detector arrangement with rotary drive in an instrument for analysis of microscale liquid sample volumes
JP2005509882A (en) * 2001-11-20 2005-04-14 バースタイン テクノロジーズ,インコーポレイティド Optical biodisc and fluid circuit for cell analysis and related methods
AU2003300382A1 (en) * 2002-12-24 2004-07-22 Tecan Trading Ag Microfluidics devices and methods for diluting samples and reagents

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6319469B1 (en) * 1995-12-18 2001-11-20 Silicon Valley Bank Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system
US6720187B2 (en) * 2000-06-28 2004-04-13 3M Innovative Properties Company Multi-format sample processing devices

Also Published As

Publication number Publication date
US20090104643A1 (en) 2009-04-23
WO2007035350A2 (en) 2007-03-29

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