WO2007032433A1

WO2007032433A1 - Method for production of recycled tobacco material

Info

Publication number: WO2007032433A1
Application number: PCT/JP2006/318254
Authority: WO
Inventors: Shigenobu Tatsuoka
Original assignee: Japan Tobacco Inc.
Priority date: 2005-09-15
Filing date: 2006-09-14
Publication date: 2007-03-22

Abstract

A method for production of a recycled tobacco material comprising the steps of extracting a natural tobacco material with an aqueous extraction solvent to give an extract containing a component of the natural tobacco material and an extraction residue, subjecting the extract or a concentrated solution of the extract to adsorption/separation with an adsorbent having a neutral polarity to reduce the content of nitrosoamine in the extract or concentrated solution, preparing a recycled tobacco web using the extraction residue, and adding at least a portion of the extract or concentration solution having a reduced nitrosoamine content to the recycled tobacco web.

Description

Specification

Method for producing recycled tobacco material

Technical field

[0001] The present invention relates to a method for producing a recycled tobacco material.

Background art

[0002] Tobacco materials such as natural tobacco leaves, chopped bones, bones, stems and roots contain various components such as nicotine, nitrosamines, hydrocarbons and proteins. In the process of manufacturing recycled tobacco materials, these components extracted from natural tobacco materials are applied back to the recycled tobacco web made from the extracted residue. Some components of these natural tobacco materials may be desirable to eliminate the power to reduce their amount for taste or other reasons, while others may not be desirable or increased.

[0003] For example, International Publication WO 02Z28209 discloses that an extract obtained by extracting tobacco with a solvent is brought into contact with an adsorbent such as activated carbon or zeolite in order to reduce tobacco-specific trosamine (TSNA). Is disclosed. This document also discloses the addition of an extract with reduced nitrosamine to the regenerated tobacco material.

U.S. Pat. No. 5810020 discloses the removal of trosamines by liquid-liquid extraction using a large amount of crown ether.

[0004] International publication WO 01Z65954 discloses that tobacco is treated with supercritical carbon dioxide to extract trosoamin and the extract is subjected to a trosamine removal process. Disclosure of the invention

[0005] Trosamine, particularly TSNA, contained in natural tobacco materials is a desirable material to remove. However, TSNA has a structure similar to that of nicotine, which is a useful component, and it is difficult to selectively remove TSNA without removing nicotine. Therefore, in the conventional method, a regenerated tobacco material that contains a significant amount of nicotine but is substantially free of TSNA is produced using an extract obtained from natural tobacco material and a fiber component that is an extraction residue. It was difficult.

International publication WO 02Z28209 allows separation of TSNA from nitric acid and sugars. There is an adsorbent that adsorbs and removes nicotine along with TSNA.

[0006] Further, in the method of US Pat. No. 5810020, since a large amount of crown ether is used, the safety aspect is not preferable. Furthermore, the method disclosed in International Publication WO 01Z65954 is not practical because of the high cost of the supercritical extraction process.

[0007] Therefore, the present invention is a comparatively simple operation, and the extract liquid power obtained from the natural tobacco material also reduces TSNA without significantly reducing the amount of cotin, and thus contains a significant amount of nicotine. However, an object of the present invention is to provide a method for producing a recycled tobacco material from which TSNA is substantially removed.

According to the present invention, (a) natural tobacco material is extracted with an aqueous extraction solvent to obtain an extract and an extraction residue containing the components of the natural tobacco material, and (b) the extract or its concentrated solution Subjecting to an adsorptive separation operation using an adsorbent exhibiting interpolarity-reducing trosamine; (c) preparing a regenerated tobacco web using the extraction residue; and (d) an extract with reduced trosamine. Or the manufacturing method of the regenerated tobacco material which includes adding at least one part of a concentrate to the said regenerated tobacco web is provided.

In the present invention, the adsorbent is a porous adsorbent composed of an acrylic or methacrylic resin, a porous adsorbent composed of a hydrophobic resin having a hydrophilic functional group on the surface, and a hydrophilic adsorbent having a hydrophobic functional group on the surface. Porous adsorbent power made of functional resin can be selected.

[0008] Further, in the present invention, adsorption separation can be performed by tip chromatography separation using a column packed with an adsorbent. In that case, it is preferable to pass the tobacco extract or the concentrated solution thereof in an amount not more than 20 times the volume of the adsorbent packed in the column through the column. In addition, the tobacco extract or its concentrate is passed through a column to obtain an effluent, and then the water eluate is combined with the effluent through three times or less of the volume of the adsorbent packed in the column. Can be added to the regenerated tobacco web.

Brief Description of Drawings

[0009] FIG. 1 is a flow diagram for explaining a method of producing a regenerated tobacco material according to an embodiment of the present invention.

FIG. 2A is a graph showing the elution concentrations of nicotine and total TSNA in Example 66 described in detail below. FIG. 2B is a graph showing the cumulative dissolution rate of nicotine and total TSNA in Example 66.

FIG. 3A is a graph showing the elution concentrations of total TSNA, sugar (glucose, fructose and sucrose) and amino acids in Example 67, which will be described in detail later.

FIG. 3B is a graph showing the cumulative elution rates of total TSNA, sugars (glucose, fructose and sucrose) and amino acids in Example 67.

BEST MODE FOR CARRYING OUT THE INVENTION

Hereinafter, the present invention will be described in more detail along various aspects.

[0011] The method of the present invention uses an adsorbent exhibiting an intermediate polarity, and the TSNA (N ′ -Nitrosonornicotine (NNN), 4- (Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone (NNK), N'--Trosoanatabine (NAT)) The regenerated tobacco material is produced by adding at least a part of the extracted liquid to a regenerated tobacco web prepared using the extraction residue.

[0012] FIG. 1 shows a flow diagram for explaining a method of producing a recycled tobacco material according to one embodiment of the present invention.

As shown in FIG. 1, first, the natural tobacco material 11 and the extraction solvent 12 are mixed and stirred to subject the natural tobacco material 11 to the extraction treatment S1.

[0014] As the natural tobacco material 11, tobacco leaves, chopped, medium bones, stems, roots, and mixtures thereof can be used. As the extraction solvent, an aqueous solvent can be used. The aqueous extraction solvent such as water may be alkaline or acidic. As an aqueous extraction solvent, a mixture of water and a water-miscible organic solvent can also be used. Examples of such organic solvents are alcohols such as ethanol. In these extraction solvents, inorganic salts such as sodium hydroxide can be dissolved. The extraction treatment S1 is usually performed at a temperature of 50 to: LOO ° C for about 5 minutes to 6 hours.

[0015] After completion of the extraction treatment S1, the obtained extraction mixture is subjected to a separation operation S2 by, for example, filtration, and divided into an extraction liquid 13 and an extraction residue 14. The extract 13 contains water-soluble components in the natural tobacco material, such as nicotine and TSNA. The extraction residue 14 consists essentially of fibers. Using this extraction residue 14, a regenerated tobacco web 15 is produced by a conventional method. The regenerated tobacco web 15 may be partially constituted by the extraction residue 14 or may be entirely constituted by the extraction residue 14.

[0016] On the other hand, the extract 13 obtained from the separation operation S2 is concentrated by an ordinary method such as a centrifugal thin film method, or the adsorption solution operation S4 using an adsorbent having intermediate polarity without being concentrated is used. Provide. In the present invention, the adsorption separation operation S4 can be performed, for example, by bringing the extract 13 into contact with an adsorbent having intermediate polarity. An adsorbent having an intermediate polarity is generally an adsorbent having an intermediate polarity between high polarity and low polarity, and is a highly porous resin based on acrylic or methacrylic resin, or styrene. Hydrophobic rosin and other hydrophobic sorbents on the surface, highly porous rosin having a hydrophilic functional group such as quaternary ammonium group, dalkamine group, iminodiacetic acid group, polyamine group and tertiary amine group, or silica Examples of the highly porous resin having a hydrophobic functional group such as octadecyl group on the surface of hydrophilic resin such as fat. By using an adsorbent with a medium polarity, TSNA can be significantly removed by reducing the nicotine loss as much as possible in the tobacco extract.

[0017] The contact between the extract 13 and the adsorbent having intermediate polarity can be performed, for example, by adding particles of the adsorbent having intermediate polarity to the extract 13 and stirring (batch type). Alternatively, the contact between the extract 13 and the adsorbent having an intermediate polarity can also be made by passing the extract through an adsorbent bed filled with particles of an adsorbent having an intermediate polarity.

[0018] A so-called advanced chromatography separation method can also be used. In this advanced chromatographic separation method, tobacco extract or its concentrate is passed through a column packed with an adsorbent, and TSNA does not contain TSNA in the column effluent, but liquid containing nicotine begins to flow out. It is a technique to collect the fraction until the start. In the advanced chromatographic separation method, the separation target liquid is adsorbed by an adsorbent in the column, and then a solvent (for example, water) different from the separation target liquid is used as a mobile phase to separate components during elution. Unlike the fee technology, the liquid to be separated (in the present invention, the tobacco extract or its concentrated liquid) itself is used as the mobile phase, and the components can be separated from the time when the liquid to be separated is loaded onto the column. is there. Furthermore, in normal chromatography, the separation target When the liquid load is increased, the resolution decreases, but in the advanced chromatographic separation, since the separation target liquid itself is used as the mobile phase, the mobile phase is different from the case of elution with a mobile phase such as water. Since the hydrogen ion concentration (pH) of each column is different, the resolution is rarely reduced even when a large amount of separation target liquid is loaded onto the column.

[0019] In the advanced chromatographic separation method used in the present invention, the tobacco extract used for separation is concentrated by a conventional method such as a centrifugal thin film method so that the concentration of soluble components is about 10 to 20% by weight. It is preferable.

[0020] The amount of the intermediate polar adsorbent used is preferably an amount corresponding to 50% or more of the weight of the soluble component in the extract 13. If the amount of the intermediate polar adsorbent is less than 50%, it becomes difficult to sufficiently remove TSNA in the extract.

[0021] In the advanced chromatographic separation method, it is desirable that the amount of the tobacco extract or its concentrate to be subjected to the separation is about 20 times or less, preferably about 12 times or less the volume of the adsorbent packed in the column. . Nicotine can be recovered almost completely (over 90% in total) by passing the entire amount of tobacco extract or its concentrate through the column and then passing water through the column. In that case, it is desirable to use water in an amount of about 3 times or more, preferably about 5 times or more the volume of the adsorbent packed in the column.

[0022] The amount of the soluble component in the extract can be determined by a freeze-drying method.

[0023] The extract thus separated by adsorption is separated from the intermediate polar adsorbent (used adsorbent 17) (S5). This separation can be performed by filtration when the contact between the extract and the intermediate polar adsorbent is carried out by adding the intermediate polar adsorbent to the extract and stirring. In addition, when the contact between the extract and the intermediate polar adsorbent is carried out by passing the extract through the intermediate polar adsorbent bed, or when using advanced chromatographic separation, the extract after the adsorption treatment is Needless to say, it flows out from the intermediate polar adsorbent bed in a state separated from the intermediate polar adsorbent. When using advanced chromatographic separation, an eluate from water can be used in combination.

[0024] The adsorption-treated extract 16 obtained in this way is concentrated by a conventional method, or a part or all of it is added to the regenerated tobacco web 15 without being concentrated (S5). Is obtained. Cigarettes made using the recycled tobacco material 18 thus obtained are TSNA in smoke generated during firing is significantly reduced.

As described above, the present invention has been described according to the embodiment, but the present invention is not limited to the above embodiment. Needless to say, the various embodiments described above can be combined.

Example

[0026] Hereinafter, the present invention will be described with reference to various examples. The present invention is not limited to these examples.

[0027] In the following example, the amount of TSNA is calculated according to Arista's time-lapse TSNA measurement method (Official Method T-309, Determination of Nitrosamines in Whole Tobacco, made by the Department or Health, dated December 31, 1999). Measured accordingly. That is, the sample solution (tobacco extract, adsorbent treatment solution, or column effluent) was subjected to LC MSZMS for measurement.

[0028] The amount of nicotine was measured by a method in accordance with DIN 10373, a German standardization organization. In other words, sodium hydroxide was added to the sample solution to make it alkaline, then hexane was added and mixed, nicotine was transferred to the hexane phase, and only the hexane phase was subjected to GCZFID for measurement.

[0029] The amount of sugar (glucose, fructose, sucrose) is measured by subjecting the sample solution to LC-RI.

[0030] Furthermore, the amount of amino acids was measured using a fully automatic amino acid analyzer (JEOL Co., Ltd. Heng LC-500).

[0031] Examples 1-11

Tobacco leaf was extracted by mixing tobacco leaf (X-KLl OOg with water lOOOOmL and stirring for 1 hour at a temperature of 25 ° C. The resulting extraction mixture was filtered, and the extract and the extraction residue were filtered. Paper from the extracted residue was obtained to obtain a regenerated tobacco web.

[0032] On the other hand, methacrylic resin in the extract in the amount (%) shown in Table 1 with respect to the weight of soluble components.

(Mitsubishi Chemical's product name Diaion HP2MG; average particle size: 250 μm or more; specific surface area: 470 mVg, no functional group), stirring at the temperature (25 ° C) shown in Table 1 (treatment time) And then filtered. The total TSNA amount and nicotine amount contained in the extract (filtrate) after the adsorption treatment were analyzed. The results are also shown in Table 1 below. Table 1 shows the total TSNA change rate and nicotine change rate. Also shown. In Table 1, untreated refers to the extract that has not been adsorbed (the same applies to the following table).

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Army army [0033] From the results shown in Table 1, the total TSNA amount was significantly decreased by using an adsorbent in an amount of 50% or more of the amount of soluble components in the extract, while the decrease rate of the nicotine amount was It can be seen that even if the treatment time is increased, it can be suppressed to less than 25%. In particular, if the amount of adsorbent used is equivalent to 500% of the amount of soluble components in the extract, it is obvious that the total TSNA amount is reduced by more than 90%.

[0034] Examples 1 to: Each of the L 1 adsorption-treated extracts was added to a regenerated tobacco web to prepare a regenerated tobacco material.

[0035] Examples 12-20

Table 2 shows acrylic resin (trade name XAD7H P, manufactured by Rohm and Haas; average particle size: 350 to 900 μm; specific surface area: 400 m ² Zg or more, no functional group) as an intermediate polar adsorbent The same operation as in Examples 1 to 11 was carried out except that the amount was used and stirring with the extract solution for the time shown in Table 2. The analysis results of the total TSNA and nicotine contained in the extract (filtrate) after the adsorption treatment are also shown in Table 2.

[Table 2]

From the results shown in Table 2, the total TSNA amount was significantly reduced by using an adsorbent in an amount of 50% or more of the amount of soluble components in the extract. It can be seen that even if the length is increased, it can be suppressed to less than 30%. In particular, the amount of adsorbent used is the extract. The amount equivalent to 500% of the amount of soluble components in the mixture is said to reduce the total TSNA amount by more than 90%.

[0037] Each of the adsorption-treated extracts of Examples 12 to 20 was added to a regenerated tobacco web to prepare a regenerated tobacco material.

[0038] Examples 21-29

As an intermediate polar adsorbent, styrene-based resin having iminodiacetic acid type functional group (trade name Diaion CR11 manufactured by Mitsubishi Chemical Co., Ltd .: average particle size 355 to 1180 μm) is used in the amount shown in Table 3, and shown in Table 3 The same operation as in Examples 1 to 11 was performed except that the mixture was stirred with the time extract. Table 3 shows the analysis results of the total TSNA and nicotine contained in the extract (filtrate) after the adsorption treatment.

[Table 3]

Results shown in Table 3 While using an adsorbent in an amount of 250% or more of the amount of soluble components in the extract, the total TSNA amount is significantly reduced, while the rate of decrease in the nicotine amount is less than the treatment time. It can be seen that even if it is made longer, it can be suppressed to 35% or less. In particular, the amount of adsorbent used is extracted If the amount of soluble components in the liquid is equivalent to 500%, the total TSNA amount will decrease by up to 80%.

[0040] Each of the adsorption-treated extracts of Examples 21 to 29 was added to a regenerated tobacco web to prepare a regenerated tobacco material.

[0041] Examples 30-38

As an intermediate polar adsorbent, a styrene-based resin having a darucamine functional group (trade name Diaion CRB02 manufactured by Mitsubishi Chemical Co., Ltd .: average particle size of 300 m or more) is used in the amount shown in Table 4, and the time extract shown in Table 4 The same operation as in Examples 1 to 11 was performed except that stirring was performed. The analysis results of the total TSNA and nicotine contained in the extract (filtrate) after the adsorption treatment are also shown in Table 4.

[Table 4]

The results shown in Table 4 While using an adsorbent in an amount of 250% or more of the amount of soluble components in the extract, the total TSNA amount is significantly reduced, while the reduction rate of the nicotine amount is less than the treatment time. It can be seen that even if it is made longer, it can be suppressed to 10% or less. In particular, the amount of adsorbent used is extracted It can be seen that when the amount of soluble components in the liquid is equivalent to 500%, the total TSNA amount decreases by 70% or more.

[0043] Each of the adsorption-treated extracts of Examples 30 to 38 was added to a regenerated tobacco web to prepare a regenerated tobacco material.

[0044] Examples 39-47

As an intermediate polar adsorbent, styrene resin having a quaternary ammonium functional group (trade name Diaion HPA25 manufactured by Mitsubishi Chemical Co., Ltd .: average particle size of 250 μm or more) is used in the amount shown in Table 5, and in Table 5 The same operations as in Examples 1 to 11 were carried out except that the extract was stirred for the indicated time. Table 5 shows the results of analysis of total TSNA and nicotine contained in the extract (filtrate) after the adsorption treatment.

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Results shown in Table 5 The use of adsorbent in an amount of 250% or more of the amount of soluble components in the extract significantly decreases the total TSNA amount, while the decrease rate of the nicotine amount decreases the processing time. It can be seen that even if it is lengthened, it can be suppressed to about 10% or less. In particular, the amount of adsorbent used is If the amount of soluble components in the extract is equivalent to 500%, the total TSNA amount will decrease by 70% or more.

[0046] Each of the adsorption-treated extracts of Examples 39 to 47 was added to a regenerated tobacco web to prepare a regenerated tobacco material.

[0047] Examples 48-56

As an intermediate polar adsorbent, silica-based rosin having a octadecyl group (trade name Bondpak C18 manufactured by Waters Co., Ltd .: average particle size: 37 to 55 / zm) is used in the amount shown in Table 6, and the time extract shown in Table 6 is used. The same operation as in Examples 1 to 11 was performed except that stirring was performed. Table 6 shows the results of analysis of total TSNA and nicotine contained in the extract (filtrate) after adsorption treatment.

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The results shown in Table 6 While using an adsorbent in an amount of 250% or more of the amount of soluble components in the extract, the total TSNA amount decreased significantly, while the rate of decrease in nicotine amount decreased with the treatment time. It can be seen that even if it is lengthened, it can be suppressed to about 10% or less. In particular, the amount of adsorbent used is If the amount of soluble components in the extract is equivalent to 500%, the total TSNA amount will decrease by 70% or more.

[0049] Each of the adsorption-treated extracts of Examples 48 to 56 was added to a regenerated tobacco web to prepare a regenerated tobacco material.

[0050] Examples 57-65 (comparative examples)

The same operation as in Examples 1 to 11 was performed except that activated alumina, which is a hydrophilic adsorbent, was used as the adsorbent in the amount shown in Table 7 and the mixture was stirred with the extract for the time shown in Table 7. Table 7 also shows the results of analysis of the total TSNA and nicotine contained in the extract (filtrate) after adsorption.

[Table 7]

As shown in Table 7, when a hydrophilic adsorbent is used, TSNA can hardly be removed. Example 66 Tobacco leaf was extracted by mixing tobacco leaf (X-KLl OOg with water lOOOmL at a temperature of 25 ° C and stirring for 1 hour. The resulting extraction mixture was filtered, Paper from the extracted residue was obtained to obtain a regenerated tobacco web.

On the other hand, the extract was concentrated under reduced pressure at about 60 ° C. by a centrifugal thin film method until the soluble component became about 15% by weight to obtain a concentrated extract (pH = 6.0). This concentrated solution (temperature 25 ° C) was subjected to advanced chromatographic separation under the following conditions.

[0053] Column: diameter 1.5 cm, length 25 cm

Adsorbent: Methacrylic resin (trade name Diaion HP2MG manufactured by Mitsubishi Chemical Corporation; average particle size: 250 μm or more; specific surface area: 470 m ² Zg, no functional group)

Filled adsorbent volume: Approximately 44mL

Flow rate: 8mLZ min.

[0054] In the advanced chromatography separation operation, the concentrated extract was first applied to the column in an amount of about 14 times or less the adsorbent packed volume. Subsequently, the cotin was completely eluted with about 5 times the volume of the adsorbent filling volume. Then, TSNA was eluted with 1% acetic acid aqueous solution.

[0055] FIGS. 2A and 2B show the elution patterns of nicotine and total TSNA. Fig. 2A is a graph plotting the concentrations of nicotine and TSNA (stock standard values) in the eluate against the amount of liquid that passed through the force ram. Fig. 2B is a graph plotting the cumulative elution rates of nicotine and total TSNA against the amount of liquid passed through the column. In V, the drift dull, curve a is for nicotine and curve b is for total TSNA.

[0056] Table 8 shows the amounts of nicotine and total TSNA eluted by each elution treatment, and the total amount and recovery rate of each elution treatment.

[Table 8] Table 8

[0057] From the results shown in Table 8, if the fraction eluted with water is used for the production of recycled tobacco, a fraction with about 80% reduction in total TSNA without nicotine loss can be obtained.ゎゎ.

[0058] Therefore, it is clear that the regenerated tobacco material produced using this fraction has a greatly reduced TSNA.

[0059] Example 67

Extraction was performed by mixing 30 kg of tobacco raw material (mixture of lamina and medium bone of yellow and burre each) with 150 L of water and stirring for 20 to 30 minutes at a temperature of about 60 ° C. The obtained extraction mixture was filtered and divided into an extract and an extraction residue. Paper from the extraction residue was obtained to obtain recycled tapaco web.

[0060] On the other hand, after removing high molecular weight substances from the extract by a centrifugal thin film method using an ultrafiltration membrane having an exclusion limit molecular weight of about 20,000, inorganic ions and the like were removed with a reverse osmosis membrane. The obtained processed extract was concentrated under reduced pressure at 60 ° C. by a centrifugal thin film method until the soluble component was about 15% by weight to obtain a concentrated extract (pH = 6.0). This concentrated solution (temperature 25 ° C) was subjected to advanced chromatographic separation under the following conditions.

[0061] Column: Diameter 7.4 cm, Length 150 cm

Filling adsorbent volume: approx.6.4 L Flow rate: 200 mLZ min.

[0062] In the advanced chromatography separation operation, first, the concentrated extract was applied to the column in an amount of about 14 times or less the adsorbent packed volume. Subsequently, the cotin was completely eluted with about 5 times the volume of the adsorbent filling volume. Then, TSNA was eluted with 1% acetic acid aqueous solution.

[0063] FIGS. 3A and 3B show the elution patterns of nicotine, total TSNA, sugars (glucose, fructose and sucrose) and total amino acids. FIG. 3A is a graph plotting the concentrations of nicotine, total TSNA, sugar (glucose, fructose and sucrose) and total amino acids (stock solution standard values) in the eluate against the amount of liquid passed through the column. Figure 3B is a graph that plots the cumulative elution rates of nicotine, total TSNA, sugars (glucose, fructose, and sucrose) and amino acids against the volume of fluid that passed through the column. In both graphs, curve a is for nicotine, curve b is for total TSNA, curve c is for sugar, and curve d is for total amino acids. Is.

[0064] Table 9 shows the total amount of nicotine, total TSNA, sugar (glucose, fructose and sucrose) and total amino acid eluted by each elution treatment, and the total amount and recovery rate of each elution treatment. Show.

[Table 9]

Table 9

[0065] From the results shown in Table 9, when the fraction eluted with water is used for the production of recycled tobacco, It is clear that a fraction with about 95% reduction in total TSNA without nicotine, sugar and amino acid loss is obtained.

[0066] Therefore, it is clear that the regenerated tobacco material produced using this fraction has a greatly reduced TSNA.

[0067] As described above, according to the present invention, TSNA can be separated without significantly reducing the amount of nicotine by a relatively simple method using the extractive force obtained from the natural tobacco material. Recycled tobacco material containing a significant amount of nicotine and substantially free of TSNA can be produced.

Claims

The scope of the claims

[1] (a) Extracting a natural tobacco material with an aqueous extraction solvent to obtain an extract containing the components of the natural tobacco material and an extraction residue;

(b) subjecting the extract or its concentrate to an adsorptive separation operation using an adsorbent exhibiting intermediate polarity to reduce trosamine;

(c) preparing a regenerated tobacco web using the extraction residue;

(d) adding at least a portion of the -trosomamine-depleted extract or concentrate to the regenerated tobacco web

A method for producing a recycled tobacco material.

[2] The adsorbent comprises a porous adsorbent made of acrylic or methacrylic resin, a porous adsorbent made of hydrophobic resin having a hydrophilic functional group on the surface, and a hydrophobic functional group on the surface. 2. The method for producing a regenerated tobacco material according to claim 1, wherein the method is selected from porous adsorbents comprising a hydrophilic resin.

[3] The method for producing a regenerated tobacco material according to [1], wherein the adsorption separation is performed by tip chromatography separation using a column packed with the adsorbent.

[4] The method for producing a regenerated tobacco material according to claim 3, wherein a tobacco extract or a concentrated liquid thereof having an amount of 20 times or less the volume of the adsorbent packed in the column is passed through the column.

[5] After passing the tobacco extract or its concentrate through the column to obtain an effluent, the effluent is discharged through the water in an amount not more than three times the volume of the adsorbent packed in the column. The method for producing a reclaimed octopus material according to claim 4, which is combined with a liquid and added to the regenerated tobacco web.