WO2007029121A3 - Novel cyclopent-2-en-1-one derivatives which are ppar receptor modulators, and use thereof in pharmaceutical or cosmetic compositions - Google Patents
Novel cyclopent-2-en-1-one derivatives which are ppar receptor modulators, and use thereof in pharmaceutical or cosmetic compositions Download PDFInfo
- Publication number
- WO2007029121A3 WO2007029121A3 PCT/IB2006/003436 IB2006003436W WO2007029121A3 WO 2007029121 A3 WO2007029121 A3 WO 2007029121A3 IB 2006003436 W IB2006003436 W IB 2006003436W WO 2007029121 A3 WO2007029121 A3 WO 2007029121A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- cosmetic compositions
- pharmaceutical
- novel
- cyclopent
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C235/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
- C07C51/47—Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/80—Unsaturated compounds containing keto groups containing rings other than six-membered aromatic rings
- C07C59/82—Unsaturated compounds containing keto groups containing rings other than six-membered aromatic rings the keto group being part of a ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention relates to novel compounds which correspond to general formula (I) below: and also to the method for preparing them, and to their use in pharmaceutical compositions for use in human or veterinary medicine, in particular in dermatology, and also in the field of cardiovascular diseases, immune diseases and/or diseases related to lipid metabolism, or alternatively in cosmetic compositions.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0507769A FR2888846B1 (en) | 2005-07-21 | 2005-07-21 | NOVEL CYCLOPENT-2-IN-1-ONE DERIVATIVES, MODULATORS OF PPAR RECEPTORS AND THEIR USE IN PHARMACEUTICAL OR COSMETIC COMPOSITIONS |
FR0507769 | 2005-07-21 | ||
US70387405P | 2005-08-01 | 2005-08-01 | |
US60/703,874 | 2005-08-01 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2007029121A2 WO2007029121A2 (en) | 2007-03-15 |
WO2007029121A3 true WO2007029121A3 (en) | 2007-06-21 |
Family
ID=37806109
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IB2006/003436 WO2007029121A2 (en) | 2005-07-21 | 2006-07-20 | Novel cyclopent-2-en-1-one derivatives which are ppar receptor modulators, and use thereof in pharmaceutical or cosmetic compositions |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2007029121A2 (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9206182B2 (en) | 2009-07-15 | 2015-12-08 | Intellikine Llc | Substituted isoquinolin-1(2H)-one compounds, compositions, and methods thereof |
US9290497B2 (en) | 2011-01-10 | 2016-03-22 | Infinity Pharmaceuticals, Inc. | Processes for preparing isoquinolinones and solid forms of isoquinolinones |
US9527847B2 (en) | 2012-06-25 | 2016-12-27 | Infinity Pharmaceuticals, Inc. | Treatment of lupus, fibrotic conditions, and inflammatory myopathies and other disorders using PI3 kinase inhibitors |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8703777B2 (en) | 2008-01-04 | 2014-04-22 | Intellikine Llc | Certain chemical entities, compositions and methods |
MX2011013016A (en) | 2009-06-05 | 2012-04-20 | Link Medicine Corp | Aminopyrrolidinone derivatives and uses thereof. |
WO2015160975A2 (en) | 2014-04-16 | 2015-10-22 | Infinity Pharmaceuticals, Inc. | Combination therapies |
CN109640999A (en) | 2016-06-24 | 2019-04-16 | 无限药品股份有限公司 | Combination treatment |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0659728A1 (en) * | 1992-09-10 | 1995-06-28 | Teijin Limited | 4-hydroxy-2-cyclopentenone derivative and carcinostatic and osteogenesis promoter containing the same |
US5981586A (en) * | 1997-05-23 | 1999-11-09 | Pershadsingh; Harrihar A. | Methods for treating proliferative and inflammatory skin diseases |
-
2006
- 2006-07-20 WO PCT/IB2006/003436 patent/WO2007029121A2/en active Application Filing
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0659728A1 (en) * | 1992-09-10 | 1995-06-28 | Teijin Limited | 4-hydroxy-2-cyclopentenone derivative and carcinostatic and osteogenesis promoter containing the same |
US5981586A (en) * | 1997-05-23 | 1999-11-09 | Pershadsingh; Harrihar A. | Methods for treating proliferative and inflammatory skin diseases |
Non-Patent Citations (3)
Title |
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FORMAN B M ET AL: "15-DEOXY-DELTA 12,14-PROSTAGLANDIN J2 IS A LIGAND FOR THE ADIPOXYTE DETERMINATION FACTOR PPARY", CELL, CELL PRESS, CAMBRIDGE, NA, US, vol. 83, 1 December 1995 (1995-12-01), pages 803 - 812, XP000575803, ISSN: 0092-8674 * |
NOYORI R.: "RATIONAL DESIGN OF ANTITUMOR PROSTAGLANDINS WITH HIGH BIOLOGICAL STABILITY", J. MED. CHEM., no. 41, 1998, pages 3084 - 3090, XP002385416 * |
STRAUS D S ET AL: "CYCLOPENTENONE PROSTAGLANDINS: NEW INSIGHTS ON BIOLOGICAL ACTIVITIES AND CELLULAR TARGETS", MEDICINAL RESEARCH REVIEWS, NEW YORK, NY, US, vol. 21, no. 3, May 2001 (2001-05-01), pages 185 - 210, XP009035137, ISSN: 0198-6325 * |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9216982B2 (en) | 2008-01-04 | 2015-12-22 | Intellikine Llc | Certain chemical entities, compositions and methods |
US9206182B2 (en) | 2009-07-15 | 2015-12-08 | Intellikine Llc | Substituted isoquinolin-1(2H)-one compounds, compositions, and methods thereof |
US9290497B2 (en) | 2011-01-10 | 2016-03-22 | Infinity Pharmaceuticals, Inc. | Processes for preparing isoquinolinones and solid forms of isoquinolinones |
US9527847B2 (en) | 2012-06-25 | 2016-12-27 | Infinity Pharmaceuticals, Inc. | Treatment of lupus, fibrotic conditions, and inflammatory myopathies and other disorders using PI3 kinase inhibitors |
Also Published As
Publication number | Publication date |
---|---|
WO2007029121A2 (en) | 2007-03-15 |
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