WO2007027916A9 - Reactifs de detection de la phosphorylation proteinique dans la voie de signalisation de carcinome - Google Patents

Reactifs de detection de la phosphorylation proteinique dans la voie de signalisation de carcinome Download PDF

Info

Publication number
WO2007027916A9
WO2007027916A9 PCT/US2006/034063 US2006034063W WO2007027916A9 WO 2007027916 A9 WO2007027916 A9 WO 2007027916A9 US 2006034063 W US2006034063 W US 2006034063W WO 2007027916 A9 WO2007027916 A9 WO 2007027916A9
Authority
WO
WIPO (PCT)
Prior art keywords
reagents
detection
signaling pathways
protein phosphorylation
carcinoma
Prior art date
Application number
PCT/US2006/034063
Other languages
English (en)
Other versions
WO2007027916A2 (fr
Inventor
Roberto Polakiewicz
Kimberly Lee
Charles Farnsworth
Ailan Guo
Klarisa Rikova
Yu Li
Albrecht Moritz
Erik Spek
Original Assignee
Cell Signaling Technology Inc
Roberto Polakiewicz
Kimberly Lee
Charles Farnsworth
Ailan Guo
Klarisa Rikova
Yu Li
Albrecht Moritz
Erik Spek
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cell Signaling Technology Inc, Roberto Polakiewicz, Kimberly Lee, Charles Farnsworth, Ailan Guo, Klarisa Rikova, Yu Li, Albrecht Moritz, Erik Spek filed Critical Cell Signaling Technology Inc
Priority to EP06802734A priority Critical patent/EP1934614A4/fr
Publication of WO2007027916A2 publication Critical patent/WO2007027916A2/fr
Priority to US12/074,228 priority patent/US20100151495A9/en
Publication of WO2007027916A9 publication Critical patent/WO2007027916A9/fr

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6806—Determination of free amino acids
    • G01N33/6812—Assays for specific amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/60—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances involving radioactive labelled substances
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Peptides Or Proteins (AREA)
PCT/US2006/034063 2005-08-31 2006-08-31 Reactifs de detection de la phosphorylation proteinique dans la voie de signalisation de carcinome WO2007027916A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP06802734A EP1934614A4 (fr) 2005-08-31 2006-08-31 Reactifs de detection de la phosphorylation proteinique dans la voie de signalisation de carcinome
US12/074,228 US20100151495A9 (en) 2005-08-31 2008-02-29 Reagents for the detection of protein phosphorylation in carcinoma signaling pathways

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71299705P 2005-08-31 2005-08-31
US60/712,997 2005-08-31

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US12/074,228 Continuation US20100151495A9 (en) 2005-08-31 2008-02-29 Reagents for the detection of protein phosphorylation in carcinoma signaling pathways

Publications (2)

Publication Number Publication Date
WO2007027916A2 WO2007027916A2 (fr) 2007-03-08
WO2007027916A9 true WO2007027916A9 (fr) 2009-04-30

Family

ID=37809521

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/034063 WO2007027916A2 (fr) 2005-08-31 2006-08-31 Reactifs de detection de la phosphorylation proteinique dans la voie de signalisation de carcinome

Country Status (2)

Country Link
EP (1) EP1934614A4 (fr)
WO (1) WO2007027916A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024042077A1 (fr) 2022-08-25 2024-02-29 Indivumed Gmbh Procédé de prédiction de la réponse à un inhibiteur de l'activité de la kinase egfr

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6924361B1 (en) * 1993-11-02 2005-08-02 Phosphoproteomics Llc Phosphopeptide-specific antibodies that are activity specific; methods of production and antibody uses
US7198896B2 (en) * 1998-09-04 2007-04-03 Cell Signaling Technology, Inc. Immunoaffinity isolation of modified peptides from complex mixtures
AU2003294828A1 (en) * 2002-12-17 2004-07-09 Sinogenomax Co. Ltd. Chinese National Human Genomecenter Specific markers for pancreatic cancer

Also Published As

Publication number Publication date
EP1934614A2 (fr) 2008-06-25
EP1934614A4 (fr) 2010-08-04
WO2007027916A2 (fr) 2007-03-08

Similar Documents

Publication Publication Date Title
EP1929003A4 (fr) Reactifs de detection de phosporylation proteinique dans des voies de signalisation de carcinome
EP1908496A4 (fr) Système de détection de position
EP2036119A4 (fr) Circuit integre tridimensionnel pour une detection d'analyte
EP1932463A4 (fr) Système de détection de position
IL181842A0 (en) Multi-threat detection system
GB0724881D0 (en) Methods for the detection of colorectal cancer
EP1942314A4 (fr) Systeme de navigation
ZA200710297B (en) Method for the segmentation of leukocytes
EP2126580A4 (fr) Reactifs permettant de detecter une phosphorylation de proteines dans des voies de signalisation de leucemie
PL2140269T3 (pl) Podpis białkowy/znaczniki do wykrywania gruczolakoraka
EP1958341A4 (fr) Detection d'echos
EP1938102A4 (fr) Détection d'un ligand cible améliorée
AU2005259012A1 (en) Analyte detection system
GB0504552D0 (en) Signal detection techniques
GB0510916D0 (en) Detection system
EP1845838A4 (fr) Systeme de determination de connaissance
GB2413227B (en) Signal processing system
EP1872134A4 (fr) Réactifs de détection de phosphorylation de protéines dans la voie de signalisation de carcinome
WO2007027916A9 (fr) Reactifs de detection de la phosphorylation proteinique dans la voie de signalisation de carcinome
GB2426419B (en) Signal processing systems
GB0412410D0 (en) Protein detection
GB0509497D0 (en) Detection system
GB0523220D0 (en) Detection system
PL374368A1 (pl) System identyfikacji obiektów
GB0511861D0 (en) Proteins

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application
NENP Non-entry into the national phase in:

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2006802734

Country of ref document: EP