WO2007017291A3 - Production of an oxaliplatin mixture and a container and a container set for said mixture - Google Patents

Production of an oxaliplatin mixture and a container and a container set for said mixture Download PDF

Info

Publication number
WO2007017291A3
WO2007017291A3 PCT/EP2006/007982 EP2006007982W WO2007017291A3 WO 2007017291 A3 WO2007017291 A3 WO 2007017291A3 EP 2006007982 W EP2006007982 W EP 2006007982W WO 2007017291 A3 WO2007017291 A3 WO 2007017291A3
Authority
WO
WIPO (PCT)
Prior art keywords
container
mixture
oxaliplatin
production
acid
Prior art date
Application number
PCT/EP2006/007982
Other languages
German (de)
French (fr)
Other versions
WO2007017291A2 (en
Inventor
Michaela Roth
Katrin Meyer-Wuelfing
Original Assignee
Hexal Ag
Michaela Roth
Katrin Meyer-Wuelfing
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hexal Ag, Michaela Roth, Katrin Meyer-Wuelfing filed Critical Hexal Ag
Priority to EP06776798A priority Critical patent/EP1916996A2/en
Priority to US12/063,531 priority patent/US20100140131A1/en
Publication of WO2007017291A2 publication Critical patent/WO2007017291A2/en
Publication of WO2007017291A3 publication Critical patent/WO2007017291A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/282—Platinum compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention relates to a method for producing an oxaliplatin aqueous solution consisting in diluting oxaliplatin by adding an acid in such a way that the oxaliplatin concentration greater than the concentration of the acid-free oxaliplatin aqueous solution is obtained. A container and a container set containing the inventive solution are also disclosed.
PCT/EP2006/007982 2005-08-11 2006-08-11 Production of an oxaliplatin mixture and a container and a container set for said mixture WO2007017291A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP06776798A EP1916996A2 (en) 2005-08-11 2006-08-11 Production of an oxaliplatin mixture and a container and a container set for said mixture
US12/063,531 US20100140131A1 (en) 2005-08-11 2006-08-11 Production of an Oxaliplatin Mixture and a Container and a Container Set for Said Mixture

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005038347A DE102005038347A1 (en) 2005-08-11 2005-08-11 Preparation of an oxaliplatin solution and container and container set with the solution
DE102005038347.5 2005-08-11

Publications (2)

Publication Number Publication Date
WO2007017291A2 WO2007017291A2 (en) 2007-02-15
WO2007017291A3 true WO2007017291A3 (en) 2007-05-24

Family

ID=37179055

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2006/007982 WO2007017291A2 (en) 2005-08-11 2006-08-11 Production of an oxaliplatin mixture and a container and a container set for said mixture

Country Status (4)

Country Link
US (1) US20100140131A1 (en)
EP (1) EP1916996A2 (en)
DE (1) DE102005038347A1 (en)
WO (1) WO2007017291A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5929607B2 (en) * 2012-08-06 2016-06-08 ニプロ株式会社 Oxaliplatin formulation

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999043355A2 (en) * 1998-02-25 1999-09-02 Sanofi-Synthelabo Formulations containing oxaliplatin
US6476068B1 (en) * 2001-12-06 2002-11-05 Pharmacia Italia, S.P.A. Platinum derivative pharmaceutical formulations
EP1466600A1 (en) * 2003-03-28 2004-10-13 Stada Arzneimittel Ag Ready-to-use oxaliplatin solutions
WO2005020980A1 (en) * 2003-08-28 2005-03-10 Mayne Pharma Pty Ltd Acid containing oxaliplatin formulations
DE102004063764A1 (en) * 2004-12-29 2006-07-13 Hexal Ag Plastic bottle for oxaliplatin

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7012072B2 (en) * 2000-12-12 2006-03-14 Debiopharm S.A. Pharmaceutical oxaliplatinum preparation for parenteral administration and method for obtaining same
CA2357955C (en) * 2001-09-28 2008-11-18 Itf Technologies Optiques Inc./Itf Optical Technologies Inc. All-fiber depolarizer
US20060063833A1 (en) * 2004-09-22 2006-03-23 Edgar Schridde Ready-to-use oxaliplatin solutions
DE102004052877B4 (en) * 2004-11-02 2008-06-19 Ebewe Pharma Ges.M.B.H. Nfg.Kg Stable aqueous formulations of a platinum derivative

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999043355A2 (en) * 1998-02-25 1999-09-02 Sanofi-Synthelabo Formulations containing oxaliplatin
US6476068B1 (en) * 2001-12-06 2002-11-05 Pharmacia Italia, S.P.A. Platinum derivative pharmaceutical formulations
US20030109515A1 (en) * 2001-12-06 2003-06-12 Pharmacia Italia, Spa. Pharmaceutical formulation of a platinum derivative
EP1466600A1 (en) * 2003-03-28 2004-10-13 Stada Arzneimittel Ag Ready-to-use oxaliplatin solutions
WO2005020980A1 (en) * 2003-08-28 2005-03-10 Mayne Pharma Pty Ltd Acid containing oxaliplatin formulations
DE102004063764A1 (en) * 2004-12-29 2006-07-13 Hexal Ag Plastic bottle for oxaliplatin

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1916996A2 *

Also Published As

Publication number Publication date
US20100140131A1 (en) 2010-06-10
EP1916996A2 (en) 2008-05-07
DE102005038347A1 (en) 2007-02-15
WO2007017291A2 (en) 2007-02-15

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